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Isolated organ preserving device and preserving method thereof

A technology of isolated organs and preservation bags, which is applied to the preservation, application, and animal husbandry of human or animal bodies, and can solve the problems that organ preservation devices cannot meet actual needs, so as to ensure chemical and biological properties, stability, The effect of ensuring oxygen supply

Active Publication Date: 2014-04-16
江苏赛谷细胞工程研究院有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Existing organ preservation devices cannot meet actual needs

Method used

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  • Isolated organ preserving device and preserving method thereof
  • Isolated organ preserving device and preserving method thereof

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Embodiment

[0025] The device in this embodiment has the characteristics of maintaining mechanical perfusion, controlling the perfusion pressure and flow rate, and monitoring the effectiveness of the perfusate in real time, such as figure 1 As shown, the structure includes: outer wall 1, inner wall 2, organ preservation tank 3, temperature controller 4, pressure detection probe interface 5, detection tank 6, peristaltic pump 7, spare tank 8, oxygenation tank 9, peristaltic pump 10, peristaltic Pump 11, central processing unit 12, touch screen 13, GPS terminal 14, power supply 15, storage battery 16, detection tank 17, temperature detection probe interface 18, pH value detection probe interface 19, pressure detection probe interface 20.

[0026] Such as figure 2 As shown, the disposable consumables used in this embodiment include an organ preservation bag 21, a standard luer connector 22, a pressure detection probe 23, a sampling bag 24, a standard luer connector 25, a connecting pipeline...

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Abstract

The invention relates to an isolated organ preserving device and a preserving method thereof, and belongs to the technical field of medical equipment. The isolated organ preserving device is structurally characterized in that continuous mechanical irrigation and membrane oxygenation are adopted, an isolated organ continuously obtains nutrients and the oxygen supply, a cell metabolite is removed in time, and a cell microenvironment is better maintained, so that the function normality is ensured. The isolated organ preserving device disclosed by the invention can be used for directly contacting the organ perfusate and the organ perfusion instrument by adopting a disposable consumable material sterilized through epoxyethane, thereby meeting the requirement for sterility of a system. Besides, the isolated organ preserving device disclosed by the invention can be used for judging the consumption of the nutrients contained in the organ perfusate and the gathering degree of metabolic wastes by monitoring the pH value of the organ perfusate in real time and can be used for abandoning the organ perfusate after a certain standard is achieved and replacing the fresh organ perfusate, thereby further ensuring the possibility of long-time preservation; the isolated organ preserving device can be used for evaluating the damage condition of the isolated organ by monitoring the front and back perfusion pressure of the isolated organ in real time and converting the perfusion resistance by combining a flow number.

Description

technical field [0001] The invention relates to an organ preservation device and a preservation method, belonging to the technical field of medical equipment. Background technique [0002] Organ transplantation is a major advance in human medical science in the 20th century, bringing hope to the treatment of various end-stage organ diseases. At present, more than 700,000 cases (times) of various organ transplants have been performed in the world. With the development of surgical techniques and the emergence of new immunosuppressants, the survival rate of organ transplantation has been greatly improved, and the number of patients waiting for transplantation is increasing year by year. In order to alleviate the contradiction of the shortage of isolated organs, donation after cardiac arrest (DCD) has gradually become an important source of organs for organ transplantation. Therefore, clinical practice puts forward higher requirements for organ preservation technology. Becaus...

Claims

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Application Information

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IPC IPC(8): A01N1/02
Inventor 吕凌鲁皓钱晓峰刘晓珊张峰王学浩
Owner 江苏赛谷细胞工程研究院有限公司
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