Super hydrophobic type SERS (Surface-enhanced Raman scattering) composite substrate

Abstract

The invention discloses a super hydrophobic type SERS (Surface-enhanced Raman scattering) composite substrate. The composite substrate comprises a base layer with a super hydrophobic surface and an SERS substrate layer, wherein the SERS substrate layer is embedded or placed on a super hydrophobic structure surface of the substrate layer, and smaller than a solution droplet formed on the super hydrophobic surface; after the solution of detected substances drips on the SERS substrate layer, spheroidal and ellipsoidal droplets are formed on the super hydrophobic surface and can be used for fully covering the SERS substrate layer, the super hydrophobic surface and tiny SERS eliminate edge effects of the prior art, and the distribution uniformity of a detected solute on the SERS substrate layer is ensured, so that the certainty and stability of detection results are improved; the spheroidal droplets with larger specific surface areas are formed by a detected solution on the super hydrophobic surface, and the concentration of the detected solute can be increased after the spheroidal droplets are concentrated, and the detection sensitivity and accuracy can be improved, therefore, in comparison with a common SERS substrate, the substrate has better enhancement effects and ultra-high sensitivity for analysis, and is applied to detection of ultra-trace samples.

Description

technical field [0001] The invention relates to the field of molecular spectrum analysis and detection, in particular to a substrate for surface-enhanced Raman scattering and a preparation method thereof. Background technique [0002] When light is irradiated on the material, elastic scattering and inelastic scattering occur. The scattered light of elastic scattering has the same wavelength as the excitation light, and the scattered light of inelastic scattering has components longer and shorter than the wavelength of excitation light, which is called Raman Scattering, the obtained spectrum is called Raman spectrum. Raman spectroscopy belongs to molecular vibration spectroscopy, which is the fingerprint of material molecules. Raman spectrometers made according to the Raman effect can be used to accurately and qualitatively identify samples. The analysis method of Raman spectroscopy generally does not require pretreatment of samples, and is easy to operate during the analysi...

AI Technical Summary

Problems solved by technology

In the SERS substrate of the above prior art, after the solution is added dropwise, the droplet will spread quickly, and in this process, an obvious edge effect will be produced, that is, the solute in the solution will gather at the edge after diffusion, causing the edge part of the solute to The concentration is higher than the middle part, which affects the stability and accuracy of detection

At the same time, the above-mentioned substrates have no concentrating effect and are less sensitive to trace substances

Images