A method for the spatially-resolved probing of bio logical tissue (102) comprises the steps of emitting, by means of at least one
light source (106), a series of light pulses into the tissue and of measuring, by means of a plurality of light detectors (108), a plurality of time-resolved responses to the light pulses scattered from the tissue. The measurement is carried out with a
temporal resolution better than 20 ps. A plurality of first responses is in response to light pulses at a first illumination band and is measured at a plurality of first detection bands. The first detection bands differ from each other and from the first illumination band in order to detect
inelastic scattering. A plurality of second responses is in response to light pulses at a second illumination band and is measured at a second detection band. The second detection band overlaps with the second illumination band in order to detect elastic scatting.
Time of flight analysis of both responses allows to e.g. use
elastic scattering for locating structures (S1, S2, S3) in the tissue (102) and for assigning them to the
inelastic scattering data.