Coronary artery dilating catheter carrying ligustrazine nanoparticles

A technology for coronary artery and dilatation catheter, which is applied in the field of medical devices, can solve the problems of drug toxicity and side effects, and achieve the effects of low drug toxicity, reduced resistance and low price.

Active Publication Date: 2014-07-30
SHANGHAI SIXTH PEOPLES HOSPITAL
View PDF9 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the drug loaded on the drug-coated balloon is generally paclitaxel and other western medicines, and the to

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Coronary artery dilating catheter carrying ligustrazine nanoparticles

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0031] In order to enable those skilled in the art to better understand the solution of the present invention, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments.

[0032] A coronary artery dilatation catheter carrying ligustrazine nanoparticles, comprising a tip 3, a guide wire channel 7, a distal portion 1 of the catheter, a balloon 4 carrying ligustrazine nanoparticles on the outer surface, a proximal portion 2 of the catheter, a side Hole 8, filling device 5, guide wire 9, filling device 5, cone joint 10, developing point 6;

[0033] Among them, the tip 3 is connected to the guide wire channel 7 and connected to the side hole 8, one end of the balloon 4 is fixed on the guide wire channel 7, and the other end is connected to the distal part of the catheter 1, and the side hole 8 is located at the distal part of the catheter outside the balloon. , the distal part 1 of the catheter is connected to the ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Particle sizeaaaaaaaaaa
Login to view more

Abstract

The invention discloses a coronary artery dilating catheter carrying ligustrazine nanoparticles. The coronary artery dilating catheter is characterized by comprising a sharp end, a guide wire channel, a far end part of the catheter, a sacculus of which the outer surface carries the ligustrazine nanoparticles, a near end part of the catheter, a side hole and a replenishing device, wherein the sharp end is connected to the guide wire channel and is communicated with the side hole; one end of the sacculus is fixed to the guide wire channel; the other end of the sacculus is connected to the far end part of the catheter; the side hole is located in the far end part of the catheter outside the sacculus; the far end part of the catheter is connected to the near end part of the catheter; the near end part of the catheter is connected to the replenishing device; the guide wire channel, the far end part of the catheter and the sacculus are not communicated. During dilation, ligustrazine nanoparticle medicines on the coronary artery dilating catheter can directly contact the inner coronary artery plaque, and the resistance is reduced; meanwhile, compared with dilating catheters of other medicines, the coronary artery dilating catheter carrying the ligustrazine nanoparticles has the advantages that the drug toxicity of the ligustrazine nanoparticle medicines is smaller, and the price is low.

Description

technical field [0001] The invention relates to a medical device, in particular to a coronary artery dilation catheter carrying ligustrazine nanoparticles. Background technique [0002] Coronary atherosclerotic heart disease is a heart disease caused by atherosclerotic lesions in the coronary arteries that cause stenosis or blockage of the vessel lumen, resulting in myocardial ischemia, hypoxia or necrosis. It is often called "coronary heart disease". [0003] At present, percutaneous transluminal coronary angioplasty (PTCA) is a new method for the treatment of coronary heart disease. It is based on the Seldinger technique that appeared in the early 1970s, specifically a percutaneous puncture The arterial vascular balloon catheter is retrogradely inserted into the coronary atherosclerotic plaque, and then the balloon is filled with diluted contrast agent, and the plaque is compressed and broken by the extrusion of the balloon, so that the narrow coronary artery cavity become...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61M29/02A61M31/00A61L29/16A61L29/14
Inventor 陈忠魏盟马根山张永军陈毅生
Owner SHANGHAI SIXTH PEOPLES HOSPITAL
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products