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Monounsaturated fatty acid for nailcare

An unsaturated fatty acid, nail technology, applied in the field of nail care, new active agent, can solve problems such as damage, achieve more embrittlement, less embrittlement, and improve aesthetic appearance

Active Publication Date: 2014-08-20
LOREAL SA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] However, to date, and to the knowledge of the inventors, there is no solution for a liquid composition acting directly on the nail, which is very sensitive to various forms of external aggression

Method used

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  • Monounsaturated fatty acid for nailcare

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0145] Evidence for petroselinic acid in nails

[0146] a-Materials and methods

[0147] 2-Amino-2-methyl-1-propanol was purchased from Sigma-Aldrich (St. Louis, USA) and methanol / HCl (3N) was purchased from Supelco (Belfont, Panama).

[0148] Pure methyl esters of cis-616:1, cis-618:1, cis-818:1 and cis-5, cis-818:2 fatty acids were purchased from Lipidox (Sweden).

[0149] Hair, nail and superficial skin samples were collected from volunteers (n=6) according to the procedure described below.

[0150] hair sampling : Using tweezers, about 20 hairs including follicles were obtained from the female's scalp. The hair was then cut with a razor blade to obtain approximately 1 cm of hair from the follicle. Hair including follicles were then pooled in 15 mL Falcon centrifuge tubes prior to methylation.

[0151] nail sampling : By scissors, 1 mm to 2 mm nails were cut from each of ten fingers of an individual and pooled in a 15 mL Falcon centrifuge tube prior to methylation...

Embodiment 2

[0174] Evaluation of the effect of dietary supplements versus placebo on nail quality

[0175] The study was performed on 132 individuals divided into 2 parallel groups (by randomly dividing each individual in the 2 groups of individuals):

[0176] - a group of 66 individuals taking a placebo, and

[0177] - A group of 66 individuals taking the food supplement to be studied.

[0178] The food supplement to be studied was a soft capsule made of isinglass containing 200 mg of coriander oil. Swallow the capsules three times daily (ie, with each meal), with a glass of water. The daily absorbed dose is 600mg of coriander oil.

[0179] The placebo was a soft capsule containing medium-chain triglycerides (caprylic acid) and made from fish gelatin. The capsules are swallowed three times a day (ie, with each meal) with a glass of water.

[0180] Treatment was carried out for 168 days.

[0181] Efficacy parameters measured included self-assessment of nail quality.

[0182] The st...

Embodiment 3

[0195] oral composition

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PUM

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Abstract

The invention relates to the cosmetic use of an effective amount of at least one monounsaturated fatty acid, of a salt thereof and / or of an ester thereof, as a nailcare active agent.

Description

technical field [0001] The present invention relates to the field of cosmetic and / or dermatological preparations and food supplements for nail care. [0002] More specifically, the present invention proposes the use of novel active agents for the treatment and / or prevention of aesthetic defects, and / or strengthening and / or improving the growth, firmness or hardness of nails. The invention also relates to methods for nail care, in particular for treating and / or preventing aesthetic defects of the nails, and / or for strengthening and / or improving the growth, firmness or hardness of the nails. Background technique [0003] The nail or nail plate is the flexible, smooth, and translucent keratinous sheet that constitutes the superficial growth of the skin, consisting of keratin and a very dense and homogeneous keratin matrix. This matrix keeps the cells together and in turn gives the nail its strength, hardness, firmness and flexibility. The nail is coated by a root sheath or st...

Claims

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Application Information

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IPC IPC(8): A61K8/92A61Q3/00A61K8/36
CPCA61K8/99A61K8/922A61Q3/00A61K8/361A61K2800/92
Inventor 奥德丽·格尼什伊莎贝尔·卡斯蒂埃尔克里斯蒂娜·克鲁兹-赫尔南德斯马乔里·玛丽-卡门·奎塔德弗雷德里克·德塔亚
Owner LOREAL SA
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