Car sickness resistant external patch and preparation method
An anti-sickness and patch technology, which is applied in the field of anti-motion sickness external patch and its production, can solve the problems of unstable drug release process, difficulty in grasping the action time, and low transdermal absorption rate, so as to improve the transdermal absorption rate, Improve the effect of potency, enhance the effect of action
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Embodiment 1
[0025] The anti-motion sickness patch for external use includes a drug-containing adhesive layer, a protective layer and a backing layer, and an anti-motion sickness drug is arranged in the drug-containing adhesive layer, and the weight ratio of the anti-motion sickness drug components is as follows: 3 parts; 5 parts of ginger; 3 parts of peppermint oil; 20 parts of pressure-sensitive adhesive; 5 parts of propylene glycol; 10 parts of anisodine; 10 parts of non-water-soluble base.
[0026] The above-mentioned components are processed according to the following steps:
[0027] A, ginger is sliced and extracted by ethanol;
[0028] B, the ginger extract is mixed with the Yangjinhua extract, and then the mixed solution is concentrated into an extract;
[0029] C. Add the extract, peppermint oil, propylene glycol, anisodine and the non-water-soluble matrix to the pressure-sensitive adhesive and stir evenly to obtain the glue;
[0030] D, the mucilage is coated on the protectiv...
Embodiment 2
[0033] The difference between this embodiment and Example 1 is that the parts by weight of the anti-motion sickness drug components are as follows: 4 parts of daphnia flower extract; 10 parts of ginger; 5 parts of peppermint oil; 30 parts of pressure-sensitive adhesive; 15 parts of propylene glycol ; 20 parts of anisodine; 15 parts of non-water-soluble matrix.
Embodiment 3
[0035] The difference between this embodiment and Example 1 is that the parts by weight of the anti-motion sickness drug components are as follows: 4 parts of datura extract; 8 parts of ginger; 4 parts of peppermint oil; 25 parts of pressure-sensitive adhesive; 10 parts of propylene glycol; 15 parts of anisodine; 13 parts of non-water-soluble matrix.
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