Car sickness resistant external patch and preparation method

An anti-sickness and patch technology, which is applied in the field of anti-motion sickness external patch and its production, can solve the problems of unstable drug release process, difficulty in grasping the action time, and low transdermal absorption rate, so as to improve the transdermal absorption rate, Improve the effect of potency, enhance the effect of action

Inactive Publication Date: 2014-10-01
四川省乐至贵均卫生材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, in order to prevent motion sickness, generally adopt the mode of taking motion sickness medicine, and in motion sickness medicine contain sedative component, people doze off on the road after taking it, and dozing off in such an environment will bring many unsafe factors, taking it at the same time It is difficult to grasp the action time of the medicine after the motion sickness medicine. If the medicine effect has not expired after the journey, it will affect the actions of the human body, which is not conducive to the protection of people's travel safety.
[0005] There are some external motion sickness patches on the existing market, which improve safety to a certain extent, but the effect of its action is not satisfactory, the release process of its medicine is unstable, and the percutaneous absorption rate is relatively low, thus It will lead to low effect and still cause motion sickness after use

Method used

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  • Car sickness resistant external patch and preparation method
  • Car sickness resistant external patch and preparation method
  • Car sickness resistant external patch and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The anti-motion sickness patch for external use includes a drug-containing adhesive layer, a protective layer and a backing layer, and an anti-motion sickness drug is arranged in the drug-containing adhesive layer, and the weight ratio of the anti-motion sickness drug components is as follows: 3 parts; 5 parts of ginger; 3 parts of peppermint oil; 20 parts of pressure-sensitive adhesive; 5 parts of propylene glycol; 10 parts of anisodine; 10 parts of non-water-soluble base.

[0026] The above-mentioned components are processed according to the following steps:

[0027] A, ginger is sliced ​​and extracted by ethanol;

[0028] B, the ginger extract is mixed with the Yangjinhua extract, and then the mixed solution is concentrated into an extract;

[0029] C. Add the extract, peppermint oil, propylene glycol, anisodine and the non-water-soluble matrix to the pressure-sensitive adhesive and stir evenly to obtain the glue;

[0030] D, the mucilage is coated on the protectiv...

Embodiment 2

[0033] The difference between this embodiment and Example 1 is that the parts by weight of the anti-motion sickness drug components are as follows: 4 parts of daphnia flower extract; 10 parts of ginger; 5 parts of peppermint oil; 30 parts of pressure-sensitive adhesive; 15 parts of propylene glycol ; 20 parts of anisodine; 15 parts of non-water-soluble matrix.

Embodiment 3

[0035] The difference between this embodiment and Example 1 is that the parts by weight of the anti-motion sickness drug components are as follows: 4 parts of datura extract; 8 parts of ginger; 4 parts of peppermint oil; 25 parts of pressure-sensitive adhesive; 10 parts of propylene glycol; 15 parts of anisodine; 13 parts of non-water-soluble matrix.

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Abstract

The invention discloses a car sickness resistant external patch which comprises a medicated viscose layer, a protective layer and a back lining layer, wherein car sickness resistant medicines are arranged in the medicated viscose layer; the components of the car sickness resistant medicines are as follows: an extracting solution of datura flowers, gingers, mint oil, pressure-sensitive adhesive, propylene glycol, anisodine and non-water soluble substrate; the car sickness resistant medicines further comprise a penetration enhancer. When the car sickness resistant external patch provided by the invention is used, a user is not sleepy, so that the security in a journey is improved, the percutaneous absorption rate is improved, the medicine releasing process is stabilized, the drug effect is improved and the action time is prolonged.

Description

technical field [0001] The invention relates to an external patch and a preparation method thereof, in particular to an anti-motion sickness external patch used on traveling roads and a preparation method thereof. Background technique [0002] Motion sickness is a disease caused by the stimulation of the vestibular nerve of the human body by any form of accelerated motion such as bumps, swings, or rotations produced by cars, ships, or airplanes. The patient initially felt epigastric discomfort, followed by nausea, pale complexion, and cold sweats, and then dizziness, depression, increased salivation, and vomiting. Due to different means of transportation, it can be called motion sickness, seasickness, airsickness (aviation motion sickness) and space motion sickness respectively. [0003] The disease often occurs after a few minutes to several hours of riding, sailing, flying and other operations. At the beginning, I felt epigastric discomfort, followed by nausea, pale comp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/70A61P1/08A61K31/439
Inventor 刘坤吕贵均
Owner 四川省乐至贵均卫生材料有限公司
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