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Traditional Chinese medicine compound preparation for treating type II diabetes mellitus and preparation method of traditional Chinese medicine compound preparation

A technology for type 2 diabetes and compound preparations, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, metabolic diseases, etc., and can solve the problems of large daily dosage, high price, and unfavorable promotion.

Inactive Publication Date: 2014-10-22
SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, most traditional Chinese medicine compound prescriptions regard improving patients' symptoms as the main curative effect index, and have limited impact on blood sugar, and lack of research on the impact on insulin resistance, the basic pathophysiology of diabetes; The taste of patent medicine is simplified, but the price is expensive, which is not conducive to promotion

Method used

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  • Traditional Chinese medicine compound preparation for treating type II diabetes mellitus and preparation method of traditional Chinese medicine compound preparation
  • Traditional Chinese medicine compound preparation for treating type II diabetes mellitus and preparation method of traditional Chinese medicine compound preparation
  • Traditional Chinese medicine compound preparation for treating type II diabetes mellitus and preparation method of traditional Chinese medicine compound preparation

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Experimental program
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Effect test

Embodiment 1

[0043] The preparation method of the Chinese medicine compound preparation of the present invention is further described by preparation examples below. Embodiment 1 Preparation of Chinese medicine compound preparation granules of the present invention (abbreviated as SGNFM-01)

[0044] (1) Take the raw materials of Chinese herbal medicine pieces of following quality:

[0045] Codonopsis 15 grams, Shanghai Leiyunshang Chinese Herbal Pieces Factory; place of origin: Gansu;

[0046] Astragalus 15g, Shanghai Leiyunshang Chinese Herbal Pieces Factory; place of origin: Inner Mongolia;

[0047] Yam 15 grams, Shanghai Sinopharm Products Co., Ltd.; place of origin: Guangxi;

[0048] Polygonatum 15 grams, Shanghai Kangqiao Chinese Herbal Pieces Co., Ltd.; place of origin: Hunan;

[0049] Coptidis 3 grams, Shanghai Leiyunshang Chinese Herbal Pieces Factory; place of origin: Sichuan;

[0050] Scutellaria baicalensis 9 grams, Shanghai Yanghetang Chinese Herbal Pieces Co., Ltd.; place o...

Embodiment 2

[0056] Embodiment 2 Preparation of Chinese medicine compound preparation mixture of the present invention

[0057] (1) Weigh the following raw materials of traditional Chinese medicines in parts by weight: Codonopsis 10g, Astragalus 10g, Chinese yam 10g, Polygonatum 10g, Coptis rhizome 2g, Scutellaria baicalensis 6g, Pueraria 10g and Guijianyu 10g;

[0058] (2) Add 3 times the volume of the medicine, soak in water for 1 hour, decoct 3 times, filter, combine the filtrate, and concentrate to 20°C when the relative density is 0.5;

[0059] (3) Centrifuge, take the supernatant, and extract twice at 100° C. with clear water under reflux, each time for 3 hours;

[0060] (4) After the extract was concentrated under reduced pressure, absolute ethanol was added and precipitated overnight at 4°C to 20°C;

[0061] (5) Take the filtrate, concentrate at 70°C to 80°C to 1 / 3 to 1 / 4 of the original volume, that is, to the mixture, which is the mixture.

Embodiment 3

[0062] Embodiment 3 preparation of Chinese medicine compound preparation decoction of the present invention

[0063] (1) Take by weighing 45g of Codonopsis pilosula, 45g of Astragalus membranaceus, 45g of Chinese yam, 45g of Rhizoma Polygonatum, 9g of Coptis chinensis, 27g of Scutellaria baicalensis, 45g of kudzu root and 45g of Guijianyu in the following parts by weight;

[0064] (2) Add 3 times the volume of medicine and soak in water for 1 hour, transfer to a casserole and boil on high heat, then simmer for 1 hour, and filter out the medicine;

[0065] (3) Add water twice the volume of the drug and continue to decoct for 1 hour, and filter out the drug solution;

[0066] (4) Combine the filtrates and obtain a total of 500ml of decoction twice a day, take it 1 hour after the meal, and take it twice a day.

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Abstract

The invention relates to a traditional Chinese medicine compound preparation for treating type II diabetes mellitus. The traditional Chinese medicine compound preparation is prepared from the following traditional Chinese medicine raw materials in parts by weight: 5-45 parts of codonopsis pilosula, 5-45 parts of astragalus membranaceus, 5-45 parts of Chinese yam, 5-45 parts of rhizoma polygonati, 1-9 parts of coptis chinensis, 3-27 parts of radix scutellariae, 5-45 parts of radix puerariae and 5-45 parts of ramulus euonymi. The invention also relates to a preparation method of the traditional Chinese medicine compound preparation. The preparation method of the traditional Chinese medicine compound preparation comprises the following steps: weighing traditional Chinese medicine raw materials, adding water for decocting the raw materials, filtering, combining filtrate and concentrating the filtrate; subsequently centrifuging, extracting supernate, concentrating, and adding pharmaceutically acceptable auxiliary materials so as to prepare a conventional preparation form of the traditional Chinese medicine compound preparation with low cost by using a conventional traditional Chinese medicine preparation method. According to the traditional Chinese medicine compound preparation, the therapeutic principle and theory of treatment determination from the spleen are taken as the guidance; the traditional Chinese medicine compound preparation has the functions of reinforcing qi and nourishing yin, strengthening the spleen and clearing heat, activating blood and reducing sugar in the clinical prevention and treatment of the type II diabetes mellitus; meanwhile, the traditional Chinese medicine compound preparation is safe, effective and relatively small in taking amount.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a compound traditional Chinese medicine preparation for treating type 2 diabetes and a preparation method thereof. Background technique [0002] In 2009, the prevalence rates of diabetes and pre-diabetes in China were 9.7% and 15.5%, respectively, surpassing the 8.3% incidence of diabetes in the United States. On March 14, 2013, the Shanghai Municipal Health and Family Planning Commission revealed that the prevalence of diabetes in Shanghai was higher than the national level in the same period, and the prevalence of diabetes was becoming younger. It is estimated that there are about 1.8 million diabetics in the city. Diabetes has now become the third major disease that threatens human health and life safety after tumors and cardiovascular and cerebrovascular diseases. Diabetic patients need lifelong monitoring and treatment. If blood sugar cannot be well controlled, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P3/10
Inventor 陆灏陶枫姚政蔡淦陈清光夏卉莉李俊燕张振华江涛唐菁
Owner SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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