New use of Flatstem Milkvetch Seed

A technology of Shayuanzi and purpose, which is applied in the field of medicine, can solve the problem that there is no application for diabetic nephropathy, and achieve the effects of reducing the level of serum creatinine, improving the quality of life and reducing the excretion of proteinuria.

Inactive Publication Date: 2014-11-05
TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] At present, there is no application of Semen Glycyrrhizae in t

Method used

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Embodiment Construction

[0018] The following describes but does not limit the present invention through the description of specific embodiments of the present invention.

[0019] The new application of the sand garden seed provided by the invention is to treat diabetic nephropathy, and obviously reduce the excretion of proteinuria.

[0020] 1. Pharmacological experiment

[0021] Shayuanzi is decocted according to the conventional method: Soak Shayuanzi for 30 minutes, decoct for 20 minutes, and the decoction is filtered and concentrated to contain 40mg of crude drug per 0.5ml.

[0022] The db / db mice were randomly divided into normal control group, model group and sand garden subgroup. 6 rats in each group, the Shayuanzi group was given the water decoction of Shayuanzi for 12 weeks, the normal control group and the model group were given the normal saline 0.5ml / 20g / day, and the Shayuanzi group was given the concentrated solution of Shayuanzi 0.5ml / 20g / day . The urinary albumin / creatinine ratio (AC...

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Abstract

The invention belongs to the field of medicines, concretely relates to a new use of Flatstem Milkvetch Seed, and especially relates to a use of Flatstem Milkvetch Seed in the preparation of diabetic nephropathy treatment medicines. A technical scheme to be solved is providing the new use of Flatstem Milkvetch Seed, and concretely the use of Flatstem Milkvetch Seed in the diabetic nephropathy treatment medicines, and the use of Flatstem Milkvetch Seed in the preparation of diabetic nephropathy treatment medicines as the only active component. The adoption of Flatstem Milkvetch Seed to treat the diabetic nephropathy reduces the proteinuria discharge amount, reduces the urinary albumin/creatinine ratio, reduces the serum creatinine level, improves the survival quality of patients, delays the diabetic nephropathy development, and has the advantages of definite curative effect, no side effects and the like.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the new application of chrysanthemum chrysanthemum, especially the application of chrysanthemum chrysanthemum in the preparation of medicine for treating diabetic nephropathy. Background technique [0002] Shayuanzi is the mature seed of Astragalus complanatus R.Br., a leguminous plant. It is warm in nature, sweet in taste, enters the liver and kidney meridians, has the effects of nourishing the liver, nourishing the kidney, improving eyesight, and solidifying essence. Hematuria, leucorrhea embolism. [0003] Diabetic nephropathy, diabetic nephropathy, referred to as DN, is one of the microvascular complications of diabetes and an important cause of death in diabetic patients. Diabetic nephropathy in a broad sense includes infectious lesions and vascular lesions. Infectious lesions include pyelonephritis and renal papillary necrosis. Vascular lesions are divided into micro...

Claims

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Application Information

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IPC IPC(8): A61K36/481A61P13/12A61P3/10
Inventor 钟森涂翔
Owner TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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