Porcine reproductive and respiratory syndrome (PRRS) egg yolk antibody oral solution and preparation method thereof
A technology of egg yolk antibody and porcine blue-ear disease, which is applied in the direction of antibodies, antiviral agents, and pharmaceutical formulas, can solve the problems of inconvenient use of porcine blue-ear disease egg yolk antibody, and improve immunity, stress ability, and biological activity Unaffected, highly bioavailable effects
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Embodiment 1
[0017] A formula for oral solution of yolk antibody against PRRS includes the following raw materials: 95 L of whole egg aqueous solution containing yolk antibody, 0.2 L of caprylic acid, 0.3 L of formaldehyde, 0.02 L of thimerosal, and 1000 units / ml of penicillin and streptomycin in the oral solution.
[0018] Its preparation method comprises the following steps:
[0019] 1) The commercially available inactivated PRRS vaccine was used for booster immunization. The vaccine dosage for each chicken was 2ml each time, and the immunization procedure was carried out three times with an interval of 10 days. When the antibody titer reached 1:256, the collection began High free eggs.
[0020] 2) Sort the collected high-free eggs, sterilize with 0.2% bromogeramine, and set aside.
[0021] 3) Acidification treatment by water dilution method: Beat 2) Bugao egg-free whole eggs into the pasteurized tank for full emulsification. The emulsification time is 7 minutes, and then add the emulsi...
Embodiment 2
[0040] A formula for oral solution of yolk antibody against PRRS includes the following raw materials: 105 L of whole egg aqueous solution containing yolk antibody, 0.2 L of octanoic acid, 0.2 L of formaldehyde, 0.01 L of thimerosal, and 800 units / ml of penicillin and streptomycin in the oral solution.
[0041] Its preparation method comprises the following steps:
[0042] 1) The commercially available inactivated PRRS vaccine was used for booster immunization. The dose of vaccine per chicken was 2ml each time, and the immunization procedure was carried out three times with an interval of 10 days. When the antibody titer reached 1:128, the collection began High free eggs.
[0043] 2) Sort the collected high-free eggs, sterilize with 0.1% bromogeramine, and set aside.
[0044] 3) Acidification treatment by water dilution method: Beat 2) Bugao egg-free whole eggs into the pasteurized tank for full emulsification, emulsification time is 10 minutes, and then add the emulsified wh...
Embodiment 3
[0063] A formula for an oral solution of yolk antibody against PRRS includes the following raw materials: 100 L of whole egg aqueous solution containing yolk antibody, 0.3 L of octanoic acid, 0.3 L of formaldehyde, 0.02 L of thimerosal, and 1000 units / ml of penicillin and streptomycin in the oral solution.
[0064] Its preparation method comprises the following steps:
[0065] 1) The commercially available inactivated PRRS vaccine was used for booster immunization. The vaccine dosage for each chicken was 2ml each time, and the immunization procedure was carried out three times with an interval of 10 days. When the antibody titer reached 1:256, the collection began High free eggs.
[0066] 2) Sort the collected high-free eggs, sterilize with 0.2% bromogeramine, and set aside.
[0067] 3) Acidification treatment by water dilution method: Beat 2) Bugao egg-free whole eggs into the pasteurized tank for full emulsification, emulsification time is 8 minutes, and then add the emulsi...
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