Medicine composition for treating functional dyspepsia and application of medicine composition

An indigestion, functional technology used in medicine

Inactive Publication Date: 2015-05-13
QINGDAO MUNICIPAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

By searching the literature at home and abroad, it is found that there is no literature report on the promotion of gastrointestinal peristalsis by dehydroerfufen

Method used

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  • Medicine composition for treating functional dyspepsia and application of medicine composition
  • Medicine composition for treating functional dyspepsia and application of medicine composition
  • Medicine composition for treating functional dyspepsia and application of medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027]

[0028] Preparation process: pass medicinal iron oxide red and dehydroephedrine through 80-mesh sieve respectively, weigh according to the prescription amount, mix evenly, then mix evenly with hydroxypropyl cyclodextrin in equal increments, and pass through 60-mesh sieve , and then mixed evenly with the rest of the excipients in the prescribed amount, measure the content of the semi-finished product, calculate the weight of the tablet, and press the tablet, that is to say.

Embodiment 2

[0030]

[0031]

[0032] Preparation process: pass medicinal iron oxide red and dehydroephedrine through 80-mesh sieve respectively, weigh according to the prescription amount, mix evenly, then mix evenly with hydroxypropyl cyclodextrin in equal increments, and pass through 60-mesh sieve , and then mixed evenly with the rest of the excipients in the prescribed amount, measure the content of the semi-finished product, calculate the weight of the tablet, and press the tablet, that is to say.

Embodiment 3

[0034]

[0035] Preparation process: Pass dehydroeuphrofen through a 100-mesh sieve, microcrystalline cellulose and low-substituted hydroxypropyl cellulose through a 80-mesh sieve, weigh the prescribed amount of dehydroeufen and low-substituted hydroxypropyl cellulose, Mix the microcrystalline cellulose evenly, add an appropriate amount of 8% hydroxypropyl methylcellulose solution to granulate, dry at 60°C, sieve the granules with 16 meshes, add the prescribed amount of magnesium stearate to the dry granules, mix well, and press into tablets. .

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PUM

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Abstract

The invention discloses a medicine composition for treating functional dyspepsia and application of the medicine composition. The medicine composition is prepared from an active component and an auxiliary material, wherein the active component comprises dehydroeffusol. According to the medicine composition, the dehydroeffusol is released by simulating a P substance and motilin, thereby promoting gastric emptying and small intestinal propulsion; a novel choice is provided for clinical treatment of functional dyspepsia.

Description

technical field [0001] The invention belongs to the technical field of medicine, in particular relates to a pharmaceutical composition for treating functional dyspepsia, in particular to a pharmaceutical composition for treating functional dyspepsia by promoting the release of substance P and motilin and its application. Background technique [0002] Functional dyspepsia is a global frequently-occurring and common disease. The main symptoms are epigastric discomfort, pain, fullness with postprandial aggravation, early satiety, and loss of appetite. The patient's dyspepsia symptoms are obvious, and recurrent for a long time, even more severe than patients with chronic gastritis and peptic ulcer, and the treatment is difficult, which seriously affects the work and quality of life of the patient. At present, it is believed that its pathogenesis is mainly related to gastrointestinal motility disorders, and some patients also have problems such as increased gastric acid secretion...

Claims

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Application Information

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IPC IPC(8): A61K31/05A61P1/14
Inventor 王莉莉董全江周建华于新娟姜维娜
Owner QINGDAO MUNICIPAL HOSPITAL
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