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A traditional Chinese medicine composition for improving hemorrhagic cystitis caused by using gefitinib to treat pancreatic cancer and its preparation method

A technology for hemorrhagic cystitis and gefitinib, which is applied in the direction of drug combination, pharmaceutical formulation, and medical raw materials derived from arthropods, etc., to achieve the effects of reasonable process design, rigorous drug use, and strong pharmacological activity

Active Publication Date: 2018-04-13
HEILONGJIANG UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] 3. Blood routine examination can be complicated by anemia symptoms;

Method used

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Examples

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Effect test

specific Embodiment approach 1

[0045] Specific embodiment one: In this embodiment, a traditional Chinese medicine composition for improving hemorrhagic cystitis caused by the use of gefitinib in the treatment of pancreatic cancer is composed of 20 parts of mixture A, 10 parts of mixture B, 1~ Composed of 5 parts of ground beetle protein extract and 2 to 5 parts of calcined oyster extract; wherein mixture A is composed of 3 to 10 parts of Shi Jianchuan, 3 to 10 parts of comfrey root, 5 to 10 parts of Loulu, and 5 to 10 parts of Dong Ling Grass, 3-10 parts of sarcophagus, 3-10 parts of Buddha's grass, 5-10 parts of Sheliugu, 5-20 parts of agrimony, 5-10 parts of weeping grass, 1-5 parts of Toosendan, 5 parts ~10 parts of woody fragrance, 5-10 parts of turmeric, 5-10 parts of Capillary, 5-10 parts of Scrophulariae, 5 parts of Dendrobium, 5-15 parts of coix seed, 1-5 parts of Jiangnan, 5-10 parts of Eight Immortals Grass, 5-10 parts of Imperata chinensis root, 5-10 parts of August Zha, 1-5 parts of Baigu Zouma,...

specific Embodiment approach 2

[0048] Embodiment 2: The difference between this embodiment and Embodiment 1 is that the composition is composed of 20 parts of mixture A, 10 parts of mixture B, 2 parts of wood beetle protein extract and 3 parts of calcined oyster extract by mass parts ; Wherein the mixture A is composed of 5 parts of Shi Jianchuan, 5 parts of comfrey root, 5 parts of Leu reed, 5 parts of Oryx chinensis, 5 parts of sarcocarpus, 5 parts of Buddha's grass, 5 parts of snake six valleys, 10 parts of agrimony , 5 parts of weeping pot grass, 2 parts of Toosendan, 5 parts of woody fragrance, 5 parts of turmeric, 5 parts of capillary, 5 parts of Scrophulariaceae, 5 parts of Dendrobium, 15 parts of coix seed, 2 parts of Jiangnan, 5 parts of Eight Immortals Grass, 5 parts Imperatae root, 5 parts August Zha, 2 parts Baigu Zouma, 5 parts Whiteback Leaf and 5 parts Celandine root; Mixture B is made from 10 parts Divine Comedy and 15 parts Coix Seed. Others are the same as in the first embodiment.

specific Embodiment approach 3

[0049] Specific embodiment three: the difference between this embodiment and specific embodiment one or two is that the composition is composed of 20 parts of mixture A, 10 parts of mixture B, 2 parts of ground beetle protein extract and 3 parts of calcined oyster in parts by mass. Composition of ointment; wherein mixture A is composed of 5 parts of Shi Jianchuan, 5 parts of comfrey root, 5 parts of leaking reed, 5 parts of Donglingcao, 5 parts of sarcocarpus, 5 parts of S. Agrimony, 10 parts of weeping pot grass, 2 parts of Toosendan, 5 parts of woody fragrance, 5 parts of turmeric, 5 parts of capillary, 10 parts of Scrophulariaceae, 5 parts of Dendrobium, 15 parts of coix seed, 5 parts of Jiangnan, 5 parts It is made of hydrangea, 5 parts of Imperata chinensis, 5 parts of August Zha, 2 parts of Baigu Zouma, 5 parts of white back leaf and 5 parts of celandine root; mixture B is made of 10 parts of Shenqu and 15 parts of coix seed. Other steps and parameters are the same as th...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for treating the hemorrhagic cystitis caused by using gefitinib for treating the pancreatic cancer and a preparation method thereof. The composition is composed of a mixture A, a mixture B, a eupolyphaga protein extract and a calcined oyster shell extract. The preparation method comprises the steps of weighing raw materials, preparing the mixture A, preparing the mixture B, weighing the eupolyphaga protein extract and the calcined oyster shell extract, and obtaining the composition. The traditional Chinese medicine herbal compound composition can be used for treating the hemorrhagic cystitis caused by using gefitinib for treating the pancreatic cancer, the preparation technology is reasonable in design, the effective content elements of the extracts are high, the pharmacological activity is higher, and few impurities are produced. The traditional Chinese medicine composition is applied in the medical field.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for improving hemorrhagic cystitis caused by using gefitinib to treat pancreatic cancer and a preparation method thereof. Background technique [0002] With the deterioration of environmental pollution, water pollution and soil pollution caused by it, the incidence of malignant tumors is getting higher and higher. Although the incidence of pancreatic cancer is relatively small, it accounts for about 2% of malignant tumors. However, pancreatic cancer has a high degree of malignancy and a high mortality rate. At present, the 5-year survival rate of surgical treatment is almost zero. Although drugs for the treatment of pancreatic cancer, such as gefitinib, have many side effects, gefitinib is suitable for the treatment of previous patients. For locally advanced or metastatic non-small cell lung cancer (NSCLC) who have received chemotherapy or are not suitable for chemotherapy, gefitinib i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P13/10A61P7/04A61K35/618A61K35/64
Inventor 姜颖贠可力白建海李尹娜
Owner HEILONGJIANG UNIV OF CHINESE MEDICINE
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