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Traditional Chinese medicine preparation for treating liver stagnation blood heat type uterine bleeding and preparation method thereof

A technology for traditional Chinese medicine preparations and uterine bleeding, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, blood diseases, etc., and can solve the problems of non-standard TCM syndrome differentiation, inconsistent diagnosis and efficacy evaluation standards, etc.

Inactive Publication Date: 2015-09-23
QINGDAO HENGBO INSTR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are still non-standard types of syndrome differentiation in traditional Chinese medicine, and the standards for diagnosis and curative effect evaluation are not uniform.

Method used

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  • Traditional Chinese medicine preparation for treating liver stagnation blood heat type uterine bleeding and preparation method thereof
  • Traditional Chinese medicine preparation for treating liver stagnation blood heat type uterine bleeding and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 3

[0078] 2.1. Tested substance: name: pill of the present invention (prepared by the method of Example 3)

[0079] 2.2. Experimental animals: Grade 1 white rabbits with large ears, 10 females, weighing 2.1-2.3kg; provided by the Experimental Animal Center of the Department of Biology, Qingdao University School of Medicine;

[0080] 2.3. Test method:

[0081] 10 healthy rabbits with intact skin were selected, and the hair on both sides of the back and spine was cut off 24 hours before the test. The left and right areas of hair removal were about 4cm×4cm. During the test, take 0.2ml of the test substance and apply it on two layers of gauze of 2.5cm×2.5cm, apply it on one side of the depilated skin surface, cover it with oil paper, and fix it with adhesive tape. The skin on the other side was used as a blank control. After 4 hours of sealing, remove the cover, wash with warm water to remove the residual test substance, treat the skin reaction at the application site 1, 24 and 48 ...

Embodiment 4

[0089] Embodiment 4: skin allergy test result

[0090] Use tablet of the present invention, carry out induction and excitation contact test, treat test mouse after 24 hours and 48 hours, all do not see phenomenons such as erythema and edema in skin, have no difference with negative control group. The results show that the tablet has close to zero skin reaction intensity, that is, no skin allergy.

Embodiment 5

[0091] Embodiment 5: Long-term toxicity test data

[0092] 1. Experimental method

[0093] The guinea pigs were randomly divided into 4 groups, 15 in each group. Apply the depilatory agent evenly on both sides of the back spine of the guinea pig, so that the range of depilation is about 40 square centimeters. Clean depilatory agent, treat each group of guinea pigs after 24 hours and apply suppository solution 0.2, 0.4 and 0.8ml of the present invention respectively, contain crude drug 92,184 and 368mg respectively, another group is coated with solvent 0.8ml every day twice, continuous 30 days, Treat the general situation of the guinea pigs, and execute the animals after the experiment for hematology, blood biochemical and pathological examinations.

[0094] 2. Results

[0095] No edema, hyperemia, erythema, bleeding spots and ulcers were found in the depilated trunk area of ​​guinea pig trunks in the above three groups of drugs. There was no significant difference between ...

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PUM

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Abstract

The invention provides a traditional Chinese medicine preparation for treating liver stagnation blood heat type dysfunctional uterine bleeding. The traditional Chinese medicine preparation comprises, by weight, the raw materials of 10-20 parts of gentians, 10-20 parts of radix paeoniae alba, 10-20 parts of fructus rubi, 10-20 parts of astragalus membranaceus, 10-20 parts of concha margaritiferallsta, 10-20 parts of scutellaria baicalensis, 10-20 parts of cyrtomium rhizome carbon, 10-20 parts of radix bupleuri, 10-20 parts of gardenias, 10-20 parts of rhizoma corydalis, 10-20 parts of herba leonuri, 10-20 parts of carbonized hair, 10-20 parts of angelica sinensis, 10-20 parts of trogopterus dung, 10-20 parts of cortex lycii radicis, 10-20 parts of dried radix rehmanniae, 10-20 parts of radix curcumae, 10-20 parts of glossy privet fruits, 10-20 parts of bighead atractylodes thizome, 10-20 parts of hairyvein agrimony, 10-20 parts of fried sanguisorba officinalis, 10-20 parts of caulis spatholobi and 10-20 parts of golden cypress. Liver stagnation blood heat type dysfunctional uterine bleeding is caused by emotional dissonance, liver depression of the fire, fire hyperactivity and blood moving, spleen health losing and the failure of the spleen to control circulating blood. The traditional Chinese medicine preparation removes heat from the liver so as to treat causes. The liver is soothed, the spleen is strengthened, blood is nourished, ying is harmonized, the menses is secured, flooding is avoided, and therefore symptoms are treated.

Description

technical field [0001] The invention relates to a traditional Chinese medicine containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine preparation for treating dysfunctional uterine bleeding of liver stagnation and blood-heat type and a preparation method thereof. Background technique [0002] Liver stagnation and blood heat type functional uterine bleeding, often due to emotional injury, liver stagnation transforms into fire, hyperactivity of fire and blood disorder, disturbance of the blood function of the spleen. The clinical manifestations are mostly irritability and irritability, dizziness and dizziness, menstrual distension and discomfort, early menstruation, increased menstrual frequency, multi-colored bright red or blood clots in menstruation, red cheeks, dry mouth, red tongue and rapid pulse. Liver depression, qi stagnation and blood stasis are red at the meeting, dry mouth like cold drinks, multi-colored deep ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P15/00A61P7/04A61K35/24A61K35/618A61K35/36
Inventor 赵玉妹
Owner QINGDAO HENGBO INSTR
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