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Traditional Chinese medicine preparation for treating kidney-yang deficiency type metrorrhagia and preparing method of traditional Chinese medicine preparation

A technology of traditional Chinese medicine preparations and uterine bleeding, which is applied in the fields of medical formulas, medical preparations containing active ingredients, blood diseases, etc., and can solve problems such as irregular classification of TCM syndromes, inconsistent diagnosis and efficacy evaluation standards, etc.

Inactive Publication Date: 2015-09-23
QINGDAO HENGBO INSTR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are still non-standard types of syndrome differentiation in traditional Chinese medicine, and the standards for diagnosis and curative effect evaluation are not uniform.

Method used

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  • Traditional Chinese medicine preparation for treating kidney-yang deficiency type metrorrhagia and preparing method of traditional Chinese medicine preparation
  • Traditional Chinese medicine preparation for treating kidney-yang deficiency type metrorrhagia and preparing method of traditional Chinese medicine preparation
  • Traditional Chinese medicine preparation for treating kidney-yang deficiency type metrorrhagia and preparing method of traditional Chinese medicine preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 3

[0076] 2.1. Tested substance: name: pill of the present invention (prepared by the method of Example 3)

[0077] 2.2. Experimental animals: Grade 1 white rabbits with large ears, 10 females, weighing 2.1-2.3kg; provided by the Experimental Animal Center of the Department of Biology, Qingdao University School of Medicine;

[0078] 2.3. Test method:

[0079] 10 healthy rabbits with intact skin were selected, and the hair on both sides of the back and spine was cut off 24 hours before the test. The left and right areas of hair removal were about 4cm×4cm. During the test, take 0.2ml of the test substance and apply it on two layers of gauze of 2.5cm×2.5cm, apply it on one side of the depilated skin surface, cover it with oil paper, and fix it with adhesive tape. The skin on the other side was used as a blank control. After 4 hours of sealing, remove the cover, wash with warm water to remove the residual test substance, treat the skin reaction at the application site 1, 24 and 48 ...

Embodiment 4

[0087] Embodiment 4: skin allergy test result

[0088] Use tablet of the present invention, carry out induction and excitation contact test, treat test mouse after 24 hours and 48 hours, all do not see phenomenons such as erythema and edema in skin, have no difference with negative control group. The results show that the tablet has close to zero skin reaction intensity, that is, no skin allergy.

Embodiment 5

[0089] Embodiment 5: Long-term toxicity test data

[0090] 1. Experimental method

[0091] The guinea pigs were randomly divided into 4 groups, 15 in each group. Apply the depilatory agent evenly on both sides of the back spine of the guinea pig, so that the range of depilation is about 40 square centimeters. Clean depilatory agent, treat each group of guinea pigs after 24 hours and apply suppository solution 0.2, 0.4 and 0.8ml of the present invention respectively, contain crude drug 92,184 and 368mg respectively, another group is coated with solvent 0.8ml every day twice, continuous 30 days, Treat the general situation of the guinea pigs, and execute the animals after the experiment for hematology, blood biochemical and pathological examinations.

[0092] 2. Results

[0093] No edema, hyperemia, erythema, bleeding spots and ulcers were found in the depilated trunk area of ​​guinea pig trunks in the above three groups of drugs. There was no significant difference between ...

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Abstract

The invention provides a traditional Chinese medicine preparation for treating kidney-yang deficiency type dysfunctional metrorrhagia. The traditional Chinese medicine preparation comprises, by weight, 10-20 parts of semen cuscutae, 10-20 parts of radix paeoniae alba, 10-20 parts of raspberry, 10-20 parts of astragalus membranaceus, 10-20 parts of herba epimedii, 10-20 parts of parasitic loranthus, 10-20 parts of fried cyrtomium fortunei, 10-20 parts of radix bupleuri, 10-20 parts of radix achyranthis bidentatae, 10-20 parts of corydalis tuber, 10-20 parts of leonurus, 10-20 parts of carbonized hair, 10-20 parts of angelica sinensis, 10-20 parts of trogopterus dung, 10-20 parts of cortex lycii radicis, 10-20 parts of rehmannia glutinosa, 10-20 parts of radix curcumae, 10-20 parts of glassy privet fruit, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of hairyvein agrimony, 10-20 parts of fried sanguisorba officinalis, 10-20 parts of prepared fleece flower root, and 10-20 parts of rhizoma curculiginis. The traditional Chinese medicine preparation is used for warming and invigorating kidney yang to cure the causes, soothing the liver and strengthening the spleen, nourishing blood and harmonizing ying to cure fundamentally, starting to warm and invigorate kidney yang, tonifying qi and producing blood, nourishing the liver and the kidney, tonifying the kidney and harmonizing chong and ren channels, menstruation is solidified, the period is orderly, and metrorrhagia and metrostaxis is cured fundamentally.

Description

technical field [0001] The invention relates to a traditional Chinese medicine containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine preparation for treating dysfunctional uterine bleeding of kidney-yang deficiency and a preparation method thereof. Background technique [0002] Since the Ming and Qing Dynasties, Chinese medicine has always believed that the kidney is the root of the viscera, the root of the twelve meridians, and the congenital root lies in the kidney. The kidney and the gate of life are based on the same qi, and are the hub of the growth and decline of yin and yang in the human body. Kidney yang dominates the yang qi of the whole body, and the evidence of yang deficiency occurs one after another when fire declines. Kidney yang deficiency, that is, deficiency of kidney yang qi, is a symptom of kidney yang qi failure. It is mostly caused by factors such as yang deficiency of fertile body, or kidney de...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P7/04A61P15/00A61K35/36A61K35/24
Inventor 赵玉妹
Owner QINGDAO HENGBO INSTR
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