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Traditional Chinese medicine preparation for treating kidney-yin deficiency-type dysfunctional uterine bleeding, and preparation method thereof

A dysfunctional and traditional Chinese medicine preparation technology, which is applied to medical formulas, medical preparations containing active ingredients, diseases, etc., can solve the problems of non-standard TCM syndrome differentiation, non-uniform diagnostic and curative effect evaluation standards, etc.

Inactive Publication Date: 2015-01-07
QINGDAO MUNICIPAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are still non-standard types of syndrome differentiation in traditional Chinese medicine, and the standards for diagnosis and curative effect evaluation are not uniform.

Method used

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  • Traditional Chinese medicine preparation for treating kidney-yin deficiency-type dysfunctional uterine bleeding, and preparation method thereof
  • Traditional Chinese medicine preparation for treating kidney-yin deficiency-type dysfunctional uterine bleeding, and preparation method thereof
  • Traditional Chinese medicine preparation for treating kidney-yin deficiency-type dysfunctional uterine bleeding, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 3

[0082] 2.1. Tested substance: name: pill of the present invention (prepared by the method of Example 3)

[0083] 2.2. Experimental animals: Grade 1 white rabbits with large ears, 10 females, weighing 2.1-2.3kg; provided by the Experimental Animal Center of the Department of Biology, Qingdao University School of Medicine;

[0084] 2.3. Test method:

[0085] 10 healthy rabbits with intact skin were selected, and the hair on both sides of the back and spine was cut off 24 hours before the test. The left and right areas of hair removal were about 4cm×4cm. During the test, take 0.2ml of the test substance and apply it on two layers of gauze of 2.5cm×2.5cm, apply it on one side of the depilated skin surface, cover it with oil paper, and fix it with adhesive tape. The skin on the other side was used as a blank control. After 4 hours of sealing, remove the cover, wash with warm water to remove the residual test substance, treat the skin reaction at the application site 1, 24 and 48 ...

Embodiment 4

[0093] Embodiment 4: skin allergy test result

[0094] Use tablet of the present invention, carry out induction and excitation contact test, treat test mouse after 24 hours and 48 hours, all do not see phenomenons such as erythema and edema in skin, have no difference with negative control group. The results show that the tablet has close to zero skin reaction intensity, that is, no skin allergy.

Embodiment 5

[0095] Embodiment 5: Long-term toxicity test data

[0096] 1. Experimental method

[0097] The guinea pigs were randomly divided into 4 groups, 15 in each group. Apply the depilatory agent evenly on both sides of the back spine of the guinea pig, so that the range of depilation is about 40 square centimeters. Clean depilatory agent, treat each group of guinea pigs after 24 hours and apply suppository solution 0.2, 0.4 and 0.8ml of the present invention respectively, contain crude drug 92,184 and 368mg respectively, another group is coated with solvent 0.8ml every day twice, continuous 30 days, Treat the general situation of the guinea pigs, and execute the animals after the experiment for hematology, blood biochemical and pathological examinations.

[0098] 2. Results

[0099] No edema, hyperemia, erythema, bleeding spots and ulcers were found in the depilated trunk area of ​​guinea pig trunks in the above three groups of drugs. There was no significant difference between ...

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PUM

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Abstract

The invention provides a traditional Chinese medicine preparation for treating kidney-yin deficiency-type dysfunctional uterine bleeding. The traditional Chinese medicine preparation comprises the following bulk drugs in parts by weight: 10-20 parts of siberian solomonseal rhizomes, 10-20 parts of white paeony roots, 10-20 parts of raspberries, 10-20 parts of astragalus membranaceus, 10-20 parts of dogwoods, 10-20 parts of radix asparagi, 10-20 parts of cyrtomium rhizome carbon, 10-20 parts of dried rehmannia, 10-20 parts of dwarf lilyturf tubers, 10-20 parts of corydalis tuber, 10-20 parts of motherworts, 10-20 parts of carbonized hair, 10-20 parts of Chinese angelica, 10-20 parts of trogopterus dung, 10-20 parts of cortex lycii radicis, 10-20 parts of polygala roots, 10-20 parts of rhizoma cyperi, 10-20 parts of Chinese magnoliavine fruits, 10-20 parts of poria cocos, 10-20 parts of hairyvein agrimony, 10-20 parts of fried sanguisorba, 10-20 parts of eclipta alba and 10-20 parts of rhizoma curculiginis. According to the traditional Chinese medicine preparation, the disease cause is solved by tonifying qi and nourishing yin and tonifying lung and kidney, the root cause is eliminated by soothing liver and strengthening spleen, and nourishing blood and smoothing nutrition qi, and the current problems are treated by strengthening thoroughfare and conception vessels and reinforcing main and collateral channels and stanching.

Description

technical field [0001] The invention relates to a traditional Chinese medicine containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine preparation for treating dysfunctional uterine bleeding of kidney yin deficiency and a preparation method thereof. Background technique [0002] Since the Ming and Qing Dynasties, Chinese medicine has always believed that the kidney is the root of the viscera, the root of the twelve meridians, and the congenital root lies in the kidney. The kidney and the gate of life are based on the same qi, and are the hub of the growth and decline of yin and yang in the human body. Kidney yang dominates the yang qi of the whole body, and the evidence of yang deficiency occurs one after another when fire declines. Lung and kidney yin deficiency refers to the syndrome of lung and kidney yin deficiency caused by exogenous evils entering the interior and turning heat into the yin, or internal injuries s...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P15/00A61P7/04A61K9/48
CPCA61K36/8969A61K9/0095A61K35/24A61K35/36A61K36/076A61K36/11A61K36/232A61K36/28A61K36/40A61K36/481A61K36/533A61K36/57A61K36/65A61K36/66A61K36/69A61K36/71A61K36/73A61K36/739A61K36/79A61K36/804A61K36/815A61K36/88A61K36/8905A61K36/8965A61K36/8968A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 李绍莉付海霞卞鲁岩
Owner QINGDAO MUNICIPAL HOSPITAL
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