Breeding sheep Chinese herbal medicine fermentation immunopotentiator preparation method and application

A technology of immune enhancer and Chinese herbal medicine, which is applied in application, animal feed, animal feed, etc., can solve the problems of restricting the promotion and application of Chinese medicine feed, simple and rough production process, and low technological content of products, so as to improve the immunity of animals and maintain Intestinal micro-ecological balance and optimal immune status, and the effect of efficiently regulating the intestinal health of sheep

Inactive Publication Date: 2015-09-30

QINGDAO JIARUI BIOLOGICAL TECH

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Problems solved by technology

However, the current level of research on traditional Chinese medicine feed additives is low, the production process is simple and rough, the product technology c...

Abstract

The invention discloses a breeding sheep Chinese herbal medicine fermentation immunopotentiator. The Breeding sheep Chinese herbal medicine fermentation immunopotentiator has the effects of prevention, health care, treatment, immunoregulation and the like and is an ideal, green, environmental, safe and novel feed additive for replacing antibiotic drugs. The fermentation Chinese herbal medicine feed additive is prepared by using compound Chinese herbal medicine including golden cypress, fevervine, heartleaf houttuynia herb, honeysuckle, isatis roots, polygonum multiflorum, licorice roots, astragalus membranaceus, epimediums, dried tangerine or orange peels, purslane, hawthorn, dandelions and the like to be subjected to the technology of 'Chinese herbal medicine ultrasonic-assisted digestion+ two-step fermentation of combining multi-strain aerobic fermentation and anaerobic fermentation'. According to the fermentation Chinese herbal medicine feed additive, the dual advantages of the Chinese herbal medicine and probiotics are achieved at the same time, the health of sheep intestinal canals is efficiently improved, the effects of treating both symptoms and root causes, consolidating basis, keeping the balance of intestinal microecology and the optimum immune state, improving the digestibility on nutrient substances, improving the immunity of the organisms of the sheep and improving the breeding benefit are achieved, the breeding risk is lowered, antibiotics can be replaced by the feed additive in use, the feed additive has no bad impact on the sheep, the use is safe, the problems of medicine residue and medicine tolerance do not exist, and the market prospect is wide.

Application Domain

Animal feeding stuff

Technology Topic

NutrientImmunity +24

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Examples

Experimental program(3)
Effect test(1)

Example Embodiment

[0018] Example 1:

[0019] A kind of Chinese herbal fermented immune enhancer for sheep, the specific preparation steps are as follows:

[0020] (1) Weighing: Accurately weigh the Chinese herbal medicines according to the following formula: 12 parts of Cortex Phellodendri, 12 parts of Chrysanthemum, 8 parts of Houttuynia cordata, 10 parts of Honeysuckle, 3 parts of Banlangen, 10 parts of Polygonum multiflorum, 6 parts of Licorice, 5 parts of Astragalus, 6 parts of goat weed, 10 parts of tangerine peel, 6 parts of purslane, 7 parts of hawthorn, 3 parts of dandelion;

[0021] (2) Preparation of compound Chinese herbal medicine: The weighed Chinese herbal medicine is crushed to 40-60 mesh, and mixed evenly to prepare compound Chinese herbal medicine;

[0022] (3) Ultrasonic-assisted leaching: add water with a mass ratio of 5 times to the compound Chinese herbal medicine powder, under the assisted action of ultrasonic waves, reflux leaching at 100 °C for 20-30 minutes, ultrasonic power 400w, frequency 25kHz;

[0023] (4) Fermentation liquid preparation: add 3.0% glucose, 3.0% yeast extract, 0.3% potassium dihydrogen phosphate, 0.02% MgSO to the extracted Chinese herbal medicine extract 4.7H 2 O, 0.01%CaCl 2 , pH adjusted to 7.0 ~ 7.2;

[0024] (5) Aerobic fermentation: choose a liquid fermenter with a liquid filling volume of 60-70% (volume ratio), inoculate Bacillus subtilis and Saccharomyces cerevisiae, the inoculum volume is 2% and 8% (volume ratio) respectively, and control the fermentation temperature 28~37℃, rotating speed 150~300rpm, ventilation rate 10~20L/min; fermented under this fermentation condition for 12h;

[0025] (6) Anaerobic fermentation: After the aerobic fermentation, inoculate Lactobacillus acidophilus and Bifidobacterium bifidum, the inoculation amount is 2% and 4% (volume ratio), the fermentation temperature is 28-37℃, and the temperature is controlled anaerobic. Fermentation for 24h;

[0026] (7) Post-fermentation treatment: after the fermentation is completed, the fermentation liquid is adsorbed with bran with a volume ratio of 1.2 times, dried in a blast dryer at 40-60 °C, and the moisture is controlled at 8-10%;

[0027] (8) Pulverization: The dried product is sieved with a 60-mesh pulverizer and pulverized to obtain a fermented Chinese herbal medicine immune enhancer for sheep.

Example Embodiment

[0028] Example 2:

[0029] A kind of Chinese herbal fermented immune enhancer for sheep, the specific preparation steps are as follows:

[0030] (1) Weighing: Accurately weigh the Chinese herbal medicines according to the following formula: 18 parts of Treats, 8 parts of Chiyateng, 12 parts of Houttuynia cordata, 6 parts of honeysuckle, 5 parts of Banlangen, 6 parts of Polygonum multiflorum, 8 parts of licorice, 3 parts of Astragalus, licorice 10 parts of goat weed, 6 parts of tangerine peel, 10 parts of purslane, 5 parts of hawthorn, 5 parts of dandelion;

[0031] (2) Preparation of compound Chinese herbal medicine: crush the weighed Chinese herbal medicine to 40-60 mesh, and mix evenly to prepare compound Chinese herbal medicine;

[0032] (3) Ultrasonic-assisted leaching: Add 10 times the mass ratio of water to the compound Chinese herbal medicine powder, under the action of ultrasonic assistance, reflux leaching at 100°C for 20-30min, ultrasonic power 400w, frequency 25kHz;

[0033] (4) Fermentation liquid preparation: add 5.0% glucose, 2.0% yeast extract, 0.5% potassium dihydrogen phosphate, 0.02% MgSO to the extracted Chinese herbal medicine extract 4.7H 2 O, 0.01%CaCl 2 , pH adjusted to 7.0 ~ 7.2;

[0034] (5) Aerobic fermentation: select a liquid fermenter with a liquid filling volume of 60-70% (volume ratio), inoculate Bacillus subtilis and Saccharomyces cerevisiae, the inoculum volume is 4% and 5% (volume ratio) respectively, and control the fermentation temperature 28~37℃, rotating speed 150~300rpm, ventilation rate 10~20L/min; fermented under this fermentation condition for 24h;

[0035] (6) Anaerobic fermentation: After the aerobic fermentation, inoculate Lactobacillus acidophilus and Bifidobacterium bifidum, the inoculation amount is 4%, 2% (volume ratio) respectively, the fermentation temperature is 28 ~ 37 ℃, and the temperature is controlled anaerobic. Fermentation for 12h;

[0036] (7) Post-fermentation treatment: after the fermentation is completed, the fermentation liquid is adsorbed with bran with a volume ratio of 2 times, dried in a blast dryer at 40-60 °C, and the moisture is controlled at 8-10%;

[0037] (8) Pulverization: The dried product is sieved and pulverized with a 60-mesh pulverizer to obtain a fermented Chinese herbal medicine immune enhancer for sheep.

Example Embodiment

[0038] Example 3:

[0039] A kind of Chinese herbal fermented immune enhancer for sheep, the specific preparation steps are as follows:

[0040] (1) Weighing: Accurately weigh the Chinese herbal medicines according to the following formula: 15 parts of Cortex Phellodendri, 10 parts of Chiyateng, 10 parts of Houttuynia cordata, 8 parts of honeysuckle, 4 parts of Banlangen, 8 parts of Polygonum multiflorum, 7 parts of licorice, 4 parts of Astragalus root, 8 parts of goat weed, 8 parts of tangerine peel, 8 parts of purslane, 6 parts of hawthorn, 4 parts of dandelion;

[0041] (2) Preparation of compound Chinese herbal medicine: The weighed Chinese herbal medicine is crushed to 40-60 mesh, and mixed evenly to prepare compound Chinese herbal medicine;

[0042] (3) Ultrasonic-assisted extraction: add water with a mass ratio of 7.5 times to the compound Chinese herbal medicine powder, and under the assistance of ultrasonic waves, reflux extraction at 100°C for 20-30min, ultrasonic power 400w, frequency 25kHz;

[0043] (4) Fermentation liquid preparation: add 4.0% glucose, 2.5% yeast extract, 0.4% potassium dihydrogen phosphate, 0.02% MgSO to the extracted Chinese herbal medicine extract 4.7H 2 O, 0.01%CaCl 2 , pH adjusted to 7.0 ~ 7.2;

[0044] (5) Aerobic fermentation: select a liquid fermenter with a liquid filling volume of 60-70% (volume ratio), inoculate Bacillus subtilis and Saccharomyces cerevisiae, the inoculum volume is 3% and 6.5% (volume ratio) respectively, and control the fermentation temperature 28~37℃, rotating speed 150~300rpm, ventilation rate 10~20L/min; fermented under this fermentation condition for 18h;

[0045] (6) Anaerobic fermentation: After the aerobic fermentation, inoculate Lactobacillus acidophilus and Bifidobacterium bifidum, the inoculation amount is 3% (volume ratio), the fermentation temperature is 28-37 °C, and the temperature-controlled anaerobic fermentation is 18h;

[0046] (7) Post-fermentation treatment: after the fermentation is completed, the fermentation liquid is adsorbed with bran with a volume ratio of 1.6 times, dried in a blast dryer at 40-60 °C, and the moisture is controlled at 8-10%;

[0047] (8) Pulverization: The dried product is sieved and pulverized with a 60-mesh pulverizer to obtain a fermented Chinese herbal medicine immune enhancer for sheep.

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Classification and recommendation of technical efficacy words

Improve digestion and absorption rate

Breeding sheep Chinese herbal medicine fermentation immunopotentiator preparation method and application

AI-Extracted Technical Summary

Problems solved by technology

Abstract

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Examples

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Example Embodiment

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Description & Claims & Application Information

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