16 results about "Isatis indigotica" patented technology

The present invention provides a high-protein bio-fermented aquatic feed and a preparation method thereof. The aquatic feed comprises the following raw materials in parts by weight: 20-30 parts of imported fish meal, 10-15 parts of compound minerals, 5-10 parts of bioactive peptides, 5-10 parts of lysine, 5-10 parts of compound trace elements, 3-8 parts of compound vitamins, 3-6 parts of herbal extracts, 2-5 parts of compound probiotics, 2-4 parts of immune polysaccharides, and 1-3 parts of compound enzymes; the herbal extracts are prepared by fermenting astragalus membranaceus, isatis root, liquorice root, calotropis gigantea, ventilago leiocarpa benth, clove, rhizoma chuanxiong, and galangal officinale. By organically integrating imported fish meal, astaxanthin-peptide chelate, herbal extracts, compound immune polysaccharides, compound probiotics and various nutrients, the present invention realizes the synergistic effect of "promoting feeding - enhancing digestion - strengthening liver and gall - enhancing immunity - resisting stress - inhibiting bacteria - stabilizing water quality", significantly improves the growth rate, survival rate and comprehensive breeding benefit of crustacean aquatic animals, and has good economic value and application prospect.

This invention discloses a method for preparing a heat-clearing and detoxifying oral liquid. Honeysuckle and Scutellaria baicalensis are pulverized and sieved, then enzymatically hydrolyzed with water, ultrasonically extracted, and filtered to obtain extract A. Scrophularia ningpoensis, Rehmannia glutinosa, Forsythia suspensa, Gardenia jasminoides, Viola yedoensis, Gentiana scabra, Isatis indigotica, Anemarrhena asphodeloides, and Ophiopogon japonicus are warm-soaked in water and flash-extracted, then filtered to obtain extract B. Gypsum is crushed, decocted with water, and filtered to obtain extract C. The extracts are combined, concentrated, and sequentially clarified using a flocculant, followed by inorganic ceramic membrane microfiltration and organic ultrafiltration. The clarified liquid is then concentrated, flavoring agents and preservatives are added, the pH is adjusted, the volume is adjusted, filtered, filled, and sterilized to obtain the finished product. This invention utilizes a composite clarification process—low-temperature ultrasonic-enzymatic extraction of honeysuckle and Scutellaria baicalensis, clarification using a flocculant, inorganic ceramic membrane microfiltration, and organic ultrafiltration—to improve the extraction rate of effective components, effectively remove large molecular impurities such as tannins, proteins, and pectin, and significantly improve the clarity and stability of the product.

This invention provides a drug for antagonizing bacterial endotoxins, its preparation method, and its application, belonging to the biomedical field. The composition consists of 25-55 parts of dried powdered traditional Chinese medicine extract, 25-70 parts of mixed essential oil powder, and 40-90 parts of lentinan powder. The traditional Chinese medicine extract is prepared by decoction of Scutellaria baicalensis, Lonicera japonica, Forsythia suspensa, and Isatis indigotica under reduced pressure at low temperature and spray drying. The mixed essential oil powder is prepared by encapsulating peppermint oil and eucalyptus oil with gelatin and hydroxypropyl cellulose and then spray drying under high pressure. This invention, through specific formulation and processing, significantly enhances the synergistic antagonistic effect of each component against endotoxins. Experiments show that this composition exhibits antagonistic activity far superior to ibuprofen in vitro; in vivo, it significantly reduces the endotoxin content in the plasma of 817 broiler chickens, rapidly alleviates LPS-induced fever and diarrhea, and improves decreased growth performance. Therefore, this invention is of great significance for reducing antibiotic dependence and improving the efficiency of livestock and poultry farming.

1. Name of the product in this design: Packaging Box (Isatis Root Tea). 2. Purpose of this design: For packaging pharmaceuticals. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

This utility model provides an integrated water and fertilizer irrigation device for Isatis indigotica. The device includes: a base plate; a water and fertilizer mixing tank and a water storage tank, both fixedly mounted on the base plate; a fertilizer storage tank, fixedly mounted on the water and fertilizer mixing tank, with its bottom connected to the mixing tank, and an installation box on the storage tank containing a drying plate; magnetic sheets on the inner wall of the installation box and the drying plate; a water supply mechanism located on the mixing tank for providing water for the water and fertilizer mixture; and an irrigation mechanism located on the mixing tank for irrigating the Isatis indigotica with water and fertilizer. This integrated water and fertilizer irrigation device for Isatis indigotica allows for better application of water and fertilizer to the plant, improving water and fertilizer utilization.

This application belongs to the field of seed detection and analysis technology, specifically relating to a method for constructing a characteristic chromatogram of Isatis indigotica seeds and a method for detecting Isatis indigotica seeds. The construction method includes the following steps: providing a reference solution; preparing a test solution using Isatis indigotica seeds; detecting the reference solution and the test solution using ultra-high performance liquid chromatography (UHPLC); importing the chromatograms obtained from detecting the reference solution and the test solution into a traditional Chinese medicine chromatographic fingerprint similarity evaluation system to establish a characteristic chromatogram of Isatis indigotica seeds; the reference solution contains alkaloids as a reference standard; the UHPLC method meets the following conditions: the stationary phase includes a C18 column; the mobile phase includes mobile phase A and mobile phase B, mobile phase A including methanol and / or mobile phase B including water; and a gradient elution program is used. This application uses UHPLC to construct a characteristic chromatogram reflecting the secondary metabolites of Isatis indigotica seeds, providing a novel reference for evaluating the quality of Isatis indigotica seeds.

The application discloses a traditional Chinese medicine exosome compound with anti-HPV and application thereof, and relates to the technical field of biotechnology.The compound comprises functional components secreted by a human cell co-culture system and a traditional Chinese medicine source extract, and the traditional Chinese medicine source extract is derived from a combined traditional Chinese medicine extract of Astragalus membranaceus, Isatis indigotica Fort., Honeysuckle and Sophora flavescens Ait., and relates to the technical field of biotechnology.The traditional Chinese medicine exosome carries natural active ingredients, and a multi-target anti-virus network is formed by beta-defensin-2 and interferon-gamma generated by co-culture with human cells.Compared with single traditional Chinese medicine extract or chemically synthesized nanoparticles, the HPV inhibition rate is increased by more than 170%, and the direct cytotoxicity of traditional Chinese medicine is reduced through an exosome delivery system, and the IC 50 >200ug / mL, which is significantly lower than that of a water decoction, and mucous membrane irritation experiments show no damage.

This invention relates to the field of feed additive technology, specifically to a compound plant-seaweed feed additive for reducing methane emissions in ruminants and its preparation method. It comprises the following raw materials in parts by weight: 40-60 parts sorghum husk powder, 30-50 parts purple sweet potato powder, 0.5-5 parts functional additives, 5-10 parts red algae, 5-10 parts brown algae, 5-12 parts *Lactobacillus plantarum*, 3-8 parts chitosan, 2-6 parts essential oil, 2-5 parts 3-nitrooxypropanol, 10-15 parts *Scutellaria baicalensis*, 8-12 parts *Codonopsis pilosula*, 3-8 parts *Isatis indigotica*, and 5-18 parts modified zeolite. Through the regulation of *Lactobacillus plantarum* and chitosan, the energy originally used to generate methane is converted into propionic acid. Propionic acid is a major gluconeogenic precursor in ruminants, which is directly converted into glucose for milk production or muscle growth.

This invention discloses a precision seeding device based on granulated Isatis indigotica seeds, comprising a base, a support frame fixedly connected to the base, a storage trough fixedly connected to the support frame, a feeding pipe at the bottom of the storage trough, the feeding pipe being fixedly connected to a fixed box, a second motor on the side of the fixed box, the output end of the second motor being fixedly connected to a round block, and the round block being rotatably connected to the fixed box. In this invention, the device integrates precision seeding, grooving, and soil covering into a single operation, eliminating the need for manual completion of seeding and soil covering processes, significantly reducing labor intensity. Simultaneously, precision control is achieved by adjusting the grooving and seed storage space using sliding blocks, reducing seed waste and avoiding the inaccurate seed quantity in traditional hill-planting techniques, thus ensuring fewer thinning steps. Furthermore, the integrated operation mode avoids the inefficiency of scattered manual operations, ensuring seeding progress and quality, and effectively alleviating planting cost pressures.

This invention relates to a traditional Chinese medicine composition for improving viral pneumonia, its preparation method, and its application, belonging to the field of traditional Chinese medicine technology. This invention provides a traditional Chinese medicine composition for improving viral pneumonia, comprising the following raw materials: Bambusa textilis, Gastrodia elata, Ziziphus jujuba, pearl, Arisaema cum bile, Bombyx mori, borneol, menthol, bezoar, pearl powder, scorpion, honeysuckle, Isatis indigotica, cicada slough, Forsythia suspensa, and licorice. The composition of this invention uses Ziziphus jujuba, bezoar, and honeysuckle as the principal herbs, clearing heat and detoxifying, resolving phlegm and calming the nerves, focusing on treating the root cause; Forsythia suspensa, Isatis indigotica, Arisaema cum bile, Bambusa textilis, Bombyx mori, Gastrodia elata, scorpion, and cicada slough as the assistant herbs, dispelling wind and heat, calming wind and resolving phlegm, enhancing the efficacy; pearl, pearl powder, borneol, and menthol as adjuvant herbs, heavily sedating and calming the mind, aromatic and opening the orifices; and licorice as the guiding herb, harmonizing the other herbs. The entire formula has the characteristics of simultaneously addressing both the exterior and interior, using both ascending and descending herbs, and combining strength and gentleness.

The application belongs to the technical field of textiles, and relates to an indigo pre-reducing agent, an indigo reducing paste and application thereof. The indigo pre-reducing agent is prepared from the following raw materials: isatis indigotica leaf, indigo fermentation liquor, glutinous rice wine and water; the indigo reducing paste is prepared from the following raw materials: the indigo pre-reducing agent, an alkaline compound, a sugar-based reducing agent, water, a penetrating agent and a natural thickening agent. The plant indigo reducing paste provided by the application can be used for printing and dyeing at room temperature, and the process of fixing color by high-temperature steaming in the printing process is omitted, so that energy consumption is saved. Meanwhile, the sugar-based reducing agent is used to replace the chemical reducing agent, so that damage of the traditional chemical reducing agent to protein fibers is avoided, and the printing paste can be applied to various fiber fabrics. The indigo pre-reducing agent and the plant indigo reducing paste provided by the application have wide application prospects in green textiles.

This application provides a CA-crosslinked, Isatis indigotica-derived carbon dots-loaded dual-responsive OPU hydrogel, its preparation method, and its applications. The hydrogel is prepared using oxidized pullulan as a backbone and chlorogenic acid as a crosslinking agent; carbon dots derived from Isatis indigotica are loaded into the hydrogel. This hydrogel exhibits excellent injectability and self-healing ability, effectively conforming to irregular wound surfaces. Under the stimulation of the acidic and oxidative microenvironment unique to infected wounds, the hydrogel gradually dissociates, achieving controlled release of Isatis indigotica carbon dots and chlorogenic acid. The Isatis indigotica carbon dots exhibit potent antibacterial activity, while chlorogenic acid synergistically works to efficiently scavenge excess reactive oxygen species and reactive nitrogen species, promoting tissue regeneration and reducing inflammatory responses. In vitro and in vivo experiments have confirmed that this hydrogel possesses excellent biocompatibility, exerting anti-infective, antioxidant, and anti-inflammatory effects in the early stages of healing, and promoting angiogenesis and accelerating wound healing in the later stages.

This invention discloses an ecological planting method for intercropping and relay cropping of Isatis indigotica with sesame or fennel, belonging to the field of ecological planting technology. The method includes the following steps: root system stratification optimization and water and fertilizer management: A wide-narrow row planting pattern is adopted, where the narrow rows (25-35cm wide) are used for planting Isatis indigotica, and the wide rows (45-60cm wide) are used for alternating planting of sesame or fennel. A root-prevention isolation strip (8-15cm wide, 20-30cm deep) is set at the boundary between the wide and narrow rows. Before sowing, a fast-acting nitrogen-phosphorus compound fertilizer for sesame or fennel is applied to the soil layer at a depth of 0-20cm at a rate of 15-25 kg / mu. This invention, by adopting a wide-narrow row planting pattern and applying fast-acting nitrogen-phosphorus compound fertilizer and slow-release organic fertilizer to different soil layers, combined with a dual-path drip irrigation system for controlled irrigation, achieves stratified management of Isatis indigotica and sesame or fennel in terms of nutrient and water niches, effectively reducing water and fertilizer competition between the two crops and improving resource utilization efficiency.

The application discloses a kind of anti-alopecia areata is extracted from Isatis indigotica Fort and Platycladus orientalis composite nanoparticles, its preparation method and application.The composite nanoparticles are composed of active ingredients, lipid materials, surfactants and water phase, the active ingredients are the mixture of Isatis indigotica Fort extract and Platycladus orientalis extract, and the composite nanoparticles are nanostructured lipid carriers.The preparation method includes dissolving active ingredients, liquid lipids and part of surfactants in organic solvents as oil phase, dissolving the remaining surfactants in water as water phase, adding oil phase to water phase, high-speed shearing emulsification, high-pressure homogenization, removing organic solvents, and cooling and solidifying.The composite nanoparticles can be used to prepare anti-alopecia areata products, significantly improve the transdermal absorption rate and follicular targeting of active ingredients, promote hair growth, and have the characteristics of high efficiency, stability and suitability for industrial production.

This application relates to a traditional Chinese medicine composition and its preparation method. The composition is made from the following raw materials and optional pharmaceutical excipients, wherein the raw materials include: Astragalus membranaceus, Lonicera japonica, Saposhnikovia divaricata, Cinnamomum cassia, Paeonia lactiflora, Forsythia suspensa, Atractylodes macrocephala, Platycodon grandiflorus, Zingiber officinale, Ziziphus jujuba, Citrus reticulata, Isatis indigotica, and Glycyrrhiza uralensis. This application also relates to the use of the above composition in the preparation of medicines for treating colds, antiviral, antipyretic, anti-inflammatory, antitussive, expectorant, analgesic, immunomodulatory, or for protecting close contacts of H1N1 influenza.