A vibrating drug storage unit of a powder mist drug delivery device

Abstract

The invention relates to a vibrating medicine storage unit for a dry powder inhalation dosing device and belongs to the field of inhalation type dosing instruments. A turning cover, a spring, a vibration gear, a turntable and an external medicine drum arranged on a flow channel lower component form the vibrating medicine storage unit for the dry powder inhalation dosing device. While impact vibration is performed on a medicine powder storage container of the medicine storage unit, a second vibrating component, namely an internal medicine drum, which can synchronously freely vibrate, is also arranged in the medicine powder storage container, so as to perform compound vibration on medicine powder in the medicine powder storage container, so that the metering accuracy of the medicine powder dose provided by the medicine storage unit in the process of medicine dosing by the whole dry powder inhalation dosing device each time is guaranteed better, the mechanical structure design change workload needed for the variation of varieties of filling medicine powder can also be reduced, and the good adaptability of the dry powder inhalation dosing device for the powder medicine varieties in a large range is improved. The vibrating medicine storage unit can be widely suitable for the fields of design and manufacture of dry powder inhalation dosing devices of various specifications.

Description

technical field [0001] The invention belongs to the field of devices for injecting media into the human body, and in particular relates to an inhalation drug delivery device for sending a specified dose of powder aerosol into the patient's lungs through the oral cavity along with the breathing air. Background technique [0002] In modern medical technology, oral or nasal inhalation can make the drug directly enter the lungs and absorb into the blood, avoiding the "first pass" effect of the liver. [0003] Clinically, pulmonary drug delivery is mainly used to treat pulmonary diseases such as asthma, chronic obstructive pneumonia, and cystic fibrosis. Due to the thin wall of alveolar epithelial cells, large surface area, and low enzyme metabolic activity, in recent years, pulmonary drug delivery has gradually become a new way for non-invasive delivery of more drugs (such as peptides and protein drugs, etc.). [0004] In the way of pulmonary drug delivery, powder aerosol has m...

AI Technical Summary

Problems solved by technology

[0011] In the inverted cone-shaped drug powder storage container in the above technical solution, once its design parameters (inverted cone angle) are determined, it can only adapt to the drug powder in a certain fluidity range. For drug powders with worse fluidity index parameters, it cannot well adapted

When the physical performance index of the filled drug powder (usually refers to the fluidity index of the drug powder) changes, only by redesigning the mechanical design parameters of the inverted cone-shaped drug powder storage container and the vibrating drug delivery unit can the drug delivery rate of each drug delivery be ensured. The metering accuracy of the powder dose supplied in the process (commonly known as the dosage of a single dose), so the powder mist drug delivery device designed and produced can only be used for drug powders with a narrow range of physical properties, and does not have a good range of medicines. Adaptability and convenience of mechanical structure parameter design adjustment

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