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Traditional Chinese medicinal composition for treating gastric ulcer, and application thereof

A composition and technology for gastric ulcer, applied in the directions of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems of long course of treatment, many side effects, low cure rate, etc., achieve simple formula, small toxic and side effects, The effect of high cure rate

Inactive Publication Date: 2015-10-28
SOUTHEAST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine treatment of gastric ulcer has advanced inspection methods, clear qualitative positioning, simple administration method, and quick effect. The recent ulcer healing rate is high, but the long-term recurrence rate is high, and the problem of many side effects is still difficult to solve
[0004] Traditional Chinese medicine treatment has the characteristics of overall regulation and multi-target effects. Patients rarely experience adverse reactions and side effects, but there are disadvantages of long treatment period and low cure rate.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation Embodiment 1

[0024] (1) Get galangal dried and pulverized, put in supercritical CO 2 In the extractor, the extraction temperature is 45°C, the extraction pressure is 20MPa, the analysis temperature is 45°C, the analysis pressure is 15MPa, the extraction time is 4 hours, the extract is collected, the extract is decompressed, vacuum-dried, and pulverized to obtain galangal. Supercritical extract; (2) Add 90% (v / v) ethanol to the dried dandelion for reflux extraction, the ratio of liquid to material is 5L / kg (v / m), extract 3 times, each time for 3 hours, combine the extracts, filter , vacuum-dried and crushed to obtain the ethanol extract of dandelion; (3) adding 90% (v / v) ethanol to the dried Evodia rutaecarpa for reflux extraction, the liquid-to-material ratio 5L / kg (v / m), extracting 3 times, each For 2 hours, combine the extracts, filter, vacuum dry, and pulverize to obtain the ethanol extract of Evodia rutaecarpa; (4) Take 11 parts of supercritical extract of galangal, 7 parts of ethanol ...

preparation Embodiment 2

[0026] (1) Get galangal dried and pulverized, put in supercritical CO 2 In the extractor, the extraction temperature is 45°C, the extraction pressure is 20MPa, the analysis temperature is 45°C, the analysis pressure is 15MPa, the extraction time is 4 hours, the extract is collected, the extract is decompressed, vacuum-dried, and pulverized to obtain galangal. Supercritical extract; (2) Add 90% (v / v) ethanol to the dried dandelion for reflux extraction, the ratio of liquid to material is 5L / kg (v / m), extract 3 times, each time for 3 hours, combine the extracts, filter , vacuum-dried and crushed to obtain the ethanol extract of dandelion; (3) adding 90% (v / v) ethanol to the dried Evodia rutaecarpa for reflux extraction, the liquid-to-material ratio 5L / kg (v / m), extracting 3 times, each For 2 hours, combine the extracts, filter, vacuum dry, and pulverize to obtain the ethanol extract of Evodia rutaecarpa; (4) take 8 parts of supercritical extract of galangal, 9 parts of ethanol e...

preparation Embodiment 3

[0028] (1) Get galangal dried and pulverized, put in supercritical CO 2 In the extractor, the extraction temperature is 45°C, the extraction pressure is 20MPa, the analysis temperature is 45°C, the analysis pressure is 15MPa, the extraction time is 4 hours, the extract is collected, the extract is decompressed, vacuum-dried, and pulverized to obtain galangal. Supercritical extract; (2) Add 90% (v / v) ethanol to the dried dandelion for reflux extraction, the ratio of liquid to material is 5L / kg (v / m), extract 3 times, each time for 3 hours, combine the extracts, filter , vacuum-dried and crushed to obtain the ethanol extract of dandelion; (3) adding 90% (v / v) ethanol to the dried Evodia rutaecarpa for reflux extraction, the liquid-to-material ratio 5L / kg (v / m), extracting 3 times, each For 2 hours, combine the extracts, filter, vacuum dry, and pulverize to obtain the ethanol extract of Evodia rutaecarpa; (4) Take 15 parts of supercritical extract of galangal, 5 parts of ethanol ...

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PUM

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating gastric ulcer, and an application thereof. The traditional Chinese medicinal composition comprises a therapeutically effective amount of Rhizoma Alpiniae Officinarum supercritical extract, and therapeutically effective amounts of Herba Taraxaci ethanol extract and Fructus Evodiae ethanol extract. The traditional Chinese medicinal composition concretely comprises, by weight, 8-15 parts of the Rhizoma Alpiniae Officinarum supercritical extract, 5-9 parts of the Herba Taraxaci ethanol extract and 3-7 parts of the Fructus Evodiae ethanol extract. A result of clinic animal researches of the traditional Chinese medicinal composition for treating gastric ulcer shows that the traditional Chinese medicinal composition has the advantages of definite therapeutic effect on gastric ulcer, small toxic side effects, simple formula, and provision of a new choice for effective treatment of gastric ulcer.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating gastric ulcer. Background technique [0002] Gastric ulcer is a common digestive tract disease with an incidence rate as high as 10%. It can occur at any age, especially in young and middle-aged people. Generally, after drug treatment, the symptoms are relieved or disappear, but they often recur, which affects the physical and mental health of patients. cause great harm. Gastric ulcers are caused by gastric acid and pepsin digesting the mucosa itself, resulting in tissue damage beyond the mucosal layer. The causes include Helicobacter pylori infection, long-term use of aspirin, corticosteroids and other drugs, or long-term smoking, drinking and drinking. Strong tea, coffee, etc. In addition, genetic factors and long-term mental stress, anxiety or mood s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61P1/04
Inventor 廖志新吴玲
Owner SOUTHEAST UNIV
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