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Medicine composition for treating nephropathy

A composition and drug technology, which can be used in drug combinations, active ingredients of heterocyclic compounds, pharmaceutical formulations, etc., can solve problems such as poor results and limited scope.

Inactive Publication Date: 2015-11-25
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the scope of western medicine is limited in the treatment of diabetic nephropathy. It basically treats symptoms by lowering blood sugar, lowering lipids, or using ACEI and ARB drugs, but the results are not good.

Method used

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  • Medicine composition for treating nephropathy
  • Medicine composition for treating nephropathy
  • Medicine composition for treating nephropathy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1: the pharmaceutical composition for the treatment of nephropathy and preparation method thereof

[0038] The composition and parts by weight of the crude drug of the pharmaceutical composition for the treatment of nephropathy are:

[0039] Herbal trumpet root 140 parts by weight 100 parts by weight of delphinium pilosula 70 parts by weight of didehydro-p-phyllotine 9 parts by weight of curcumol 5 parts by weight of protopetine 2 parts by weight;

[0040] Preparation:

[0041] (1) According to the ratio of raw materials, take delphinium and lotus root, mix well, first use 50% ethanol as a solvent, and extract by warm soaking at 55°C. The number of extractions is 4 times, and the extraction time for each time is For 3 hours, the amount of solvent used each time is 20 times of the total weight of delphinium pilosula and hair lotus medicinal materials, and filtered to obtain medicinal residue A and extract, and the extract is recovered with ethanol, concentrat...

Embodiment 2

[0044] Embodiment 2: the pharmaceutical composition for the treatment of nephropathy and preparation method thereof

[0045] The composition and parts by weight of the crude drug of the pharmaceutical composition for the treatment of nephropathy are:

[0046] Herbal trumpet root 130 parts by weight 110 parts by weight of delphinium pilosula 60 parts by weight of didehydro-p-phyllotine 10 parts by weight of curcumol 4 parts by weight of protopetine 3 parts by weight;

[0047] Preparation:

[0048] (1) According to the ratio of raw materials, take delphinium and lotus root, mix well, first use 50% ethanol as a solvent, and extract by warm soaking at 55°C. The number of extractions is 4 times, and the extraction time for each time is For 3 hours, the amount of solvent used each time is 20 times of the total weight of delphinium pilosula and hair lotus medicinal materials, and filtered to obtain medicinal residue A and extract, and the extract is recovered with ethanol, concentra...

Embodiment 3

[0051] Embodiment 3: the pharmaceutical composition for the treatment of nephropathy and preparation method thereof

[0052] The composition and parts by weight of the crude drug of the pharmaceutical composition for the treatment of nephropathy are:

[0053] 150 parts by weight of the medicine trumpet root 90 parts by weight of Delphinium pilosula 80 parts by weight of didehydro-p-phyllotine 8 parts by weight of curcumol 6 parts by weight of protopetine 1 part by weight;

[0054] Preparation:

[0055] (1) According to the ratio of raw materials, take delphinium and lotus root, mix well, first use 50% ethanol as a solvent, and extract by warm soaking at 55°C. The number of extractions is 4 times, and the extraction time for each time is For 3 hours, the amount of solvent used each time is 20 times of the total weight of delphinium pilosula and hair lotus medicinal materials, and filtered to obtain medicinal residue A and extract, and the extract is recovered with ethanol, con...

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PUM

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Abstract

The invention discloses a medicine composition for treating nephropathy. The medicine composition is prepared by taking piptostegia root, herba delphinii, picris japonica, didehydrotuberostemonine, curcumenol and protostemonine as crude drugs through a proper ratio; the medicine composition can be prepared into various dosages according to the conventional preparation technology, and has an obvious effect in treating nephropathy.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating nephropathy and a preparation method thereof. Background technique [0002] Diabetic nephropathy is also called diabetic glomerulosclerosis. Diabetic nephropathy is the most common microvascular complication of diabetes, and it is also the root cause of chronic renal failure. The course of diabetic nephropathy is generally 10 to 20 years, and the incidence of diabetic nephropathy reaches about 50%. Patients with diabetic nephropathy have proteinuria for about 7 years, and half of them will become end-stage renal disease. According to authoritative data, the incidence of diabetic nephropathy in diabetic patients within 10 to 20 years reaches 47.66%, and the lesions show progressive development, and end-stage renal failure will occur within 5 to 10 years. Clinical pathological studies of western medicine b...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61P13/12A61K31/35A61K31/55
Inventor 张秀华
Owner JINAN XINGYI MEDICAL TECH
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