Method for extracting biomarker for diagnosing pancreatic cancer, computing device therefor, biomarker for diagnosing pancreatic cancer and device for diagnosing pancreatic cancer including the same

A technology of phosphonates and complexes, applied in the field of bar soap compositions, can solve the problems of reducing the antimicrobial effect of bar soap compositions, aggravating ZPT instability, ZPT loss, etc.

Active Publication Date: 2015-11-25
THE PROCTER & GAMBLE COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The presence of the aforementioned compounds in bar soap compositions also exacerbates ZPT instability and leads to

Method used

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  • Method for extracting biomarker for diagnosing pancreatic cancer, computing device therefor, biomarker for diagnosing pancreatic cancer and device for diagnosing pancreatic cancer including the same
  • Method for extracting biomarker for diagnosing pancreatic cancer, computing device therefor, biomarker for diagnosing pancreatic cancer and device for diagnosing pancreatic cancer including the same
  • Method for extracting biomarker for diagnosing pancreatic cancer, computing device therefor, biomarker for diagnosing pancreatic cancer and device for diagnosing pancreatic cancer including the same

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example

[0121] I. Preformation of zinc phosphonate complexes

[0122] The Zn-HEDP complex can then be preformed by using the following starting materials:

[0123] Table I: Zn / HEDP precomplex formation:

[0124] material name

Nominal (%)

Target weight(g)

HEDP-4Na

10.00

80.00

ZnSO4·7H2O*

7.78

62.24

water (DI)

82.22

657.76

total

100.00

800.00

[0125] *Analytical grade, purchased from Tianjin Jiaxin Chemicals Glass Instrument Trading Co., Ltd.

[0126] The Zn-HEDP complex of the present invention is preformed according to the following procedure:

[0127] - Pre-weighed 300 grams of deionized (DI) water, referred to herein as "DI Water 1";

[0128] ●Pre-weighed 80 grams of HEDP-4Na;

[0129] Vortex using a magnetic stir bar to stir, and then slowly add the pre-weighed HEDP-4Na into DI water 1;

[0130] • Keep stirring until the solution becomes clear with no visible particles, which is referred t...

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Abstract

Disclosed are a method for extracting a biomarker for diagnosing pancreatic cancer, a computing device therefor, a biomarker for diagnosing pancreatic cancer and a device for diagnosing pancreatic cancer including the same. More particularly, disclosed are a method for extracting a biomarker for diagnosing pancreatic cancer using genes specifically expressed in pancreatic cancer patients or microRNAs obtained from blood or tissues paired with the genes, a computing device therefor, a biomarker for diagnosing pancreatic cancer and a device for diagnosing pancreatic cancer including the same.

Description

technical field [0001] The present invention relates to personal cleansing compositions, more particularly bar soap compositions, comprising zinc pyrithione and a metal-phosphonate complex and having enhanced resistance to discoloration, extended shelf life and / or increased antimicrobial properties effect. Background technique [0002] It has been noted that pyrithione (also known as 1-hydroxy-2-pyridinethione, 2-pyridinethiol-1-oxide, 2-mercaptopyridine-N-oxide, pyridine-2-thione-N -oxide, pyrithione-N-oxide, 2-pyridinethione, pyrithione, or simply "PT") for bactericidal and fungicidal activity. Pyrithione is a bidentate ligand that forms stable complexes with most transition metals. Metallation of pyrithione often results in highly enhanced biocidal activity. Metal salts of pyrithione such as, for example, sodium pyrithione, magnesium pyrithione, barium pyrithione, bismuth pyrithione, strontium pyrithione, copper pyrithione, zinc pyrithione, cadmium pyrithione, and Zir...

Claims

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Application Information

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IPC IPC(8): A61K8/49A61K8/24A61K8/02
Inventor 姜春鹏刘喆王娟徐秀军K·S·韦
Owner THE PROCTER & GAMBLE COMPANY
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