Method for preparing enramycin premix

A technology of enramycin and premix, which is applied in the field of preparing enramycin premix, can solve the problems of affecting the stability of enramycin, affecting the quality, sales and use, etc., and achieves low cost and good quality. Guarantee, change the effect of stability

Inactive Publication Date: 2015-12-02
SHIJIAZHUANG GAOKE ANIMAL HEALTH PROD CO LTD
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  • Summary
  • Abstract
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AI Technical Summary

Problems solved by technology

[0003] Although enramycin has good development prospects at home and abroad, due to the instability of enramycin premix products, the content will be degraded after a period of time, which will affect the storage and transportation of enramycin. The stability in the medium, which in turn affects its quality and sales and use

Method used

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  • Method for preparing enramycin premix
  • Method for preparing enramycin premix
  • Method for preparing enramycin premix

Examples

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Embodiment 1

[0018] In the embodiment of the present invention, get the enramycin fermented liquid that 2 batches of fermentations complete, process as follows:

[0019] Control group: without pretreatment, according to the existing process.

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Abstract

The invention discloses a method for preparing enramycin premix. The method comprises the steps that the temperature of enramycin fermentation liquor is firstly increased to 70-75 DEG C, then complex antioxidants of which the mass accounts for 0.5-1.0% of that of the enramycin fermentation liquor and filter aid of which the mass accounts for 0-12% of that of the enramycin fermentation liquor are added, and the mixture is stirred fully and evenly; frame filter and flash drying are performed on the evenly stirred mixture, auxiliary materials are added in the mixture for dilution, and then the enramycin premix is prepared. The method is simple, easy to operate and low in cost, and compared with finished enramycin premix which is not preprocessed, the enramycin premix has the advantages that the degradation degree is obviously weakened and the stability is obviously improved.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a method for preparing enramycin premix. Background technique [0002] Enramycin, also known as enramycin, enramycin, enleimycin, and duramycin, is obtained from the fermentation of actinomyces (Streptomyces fungicidicus), and is a polypeptide combined with unsaturated fatty acids and more than a dozen amino acids. Antibiotics, the main components of which are enramycin A and B, are used in the form of their hydrochloride salts. Originally developed in 1966 by Takeda Pharmaceutical Co., Ltd. of Japan. It was officially registered in Japan in 1974, and has since been registered and widely used in many countries. In 1993, the Ministry of Agriculture of my country approved the registration of the drug in my country, and the registered name was Enlamycin Premix (Enlading), which was used as a drug feed additive. In 2000, Schering-Plough acquired Japan's Takeda Animal Health Products Compa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K1/17A23K1/16A23K1/175A23K1/00A23K1/14A23K20/195
CPCY02P60/87
Inventor 巴东风程青芳高晓华李海亭
Owner SHIJIAZHUANG GAOKE ANIMAL HEALTH PROD CO LTD
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