Phenobarbital oral cavity instant membrane and preparation method thereof

A technology of oral instant film and phenobarbital, which is applied in the direction of pharmaceutical formulations, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the complex preparation process of orally disintegrating tablets and orally dissolving tablets , Oral liquid is inconvenient to carry, unfavorable quantitative administration and other issues
CN105147646AActive Publication Date: 2015-12-16HEFEI HUAFANG PHARMA SCI & TECH
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
HEFEI HUAFANG PHARMA SCI & TECH
Publication Date
2015-12-16

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Abstract

The invention belongs to the field of pharmaceutic preparations, particularly relates to a phenobarbital oral cavity instant membrane and a preparation method thereof. The instant membrane comprises the following components in parts by weight: 5-10 parts of phenobarbital, 10-50 parts of a film-forming material, 1-10 parts of a plasticizer and 1-6 parts of a saliva irritant. According to the phenobarbital oral cavity instant membrane and the preparation method thereof, provided by the invention, due to the form of the membrane, drug administration can be carried out without water, the membrane can melt quickly in the oral cavity, that drugs are hidden in or spat out from the oral cavity of a patient is avoided, and the medication compliance of the patient is improved; besides, the main drugs of the instant membrane prepared by adopting the preparation method provided by the invention can be uniformly dispersed in a film-forming material, the finished product is good in appearance, the main drugs can quickly dissolve and is good in stability, the dosage of the product is accurate, dust flying in the production process is hardly caused, and the problem of labor protection and environmental pollution is solved.
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Description

technical field

[0001] The invention belongs to the field of chemical pharmacy, and in particular relates to a phenobarbital oral instant film and a preparation method thereof. Background technique

[0002] In medicine, the jaundice of newborns under the full moon (within 28 days of birth) is called neonatal jaundice. It is a disease characterized by jaundice on the skin, mucous membranes and sclera. The disease can be divided into physiological and pathological. Physiological jaundice appears 2 to 3 days after birth, peaks at 4 to 6 days, subsides at 7 to 10 days, and lasts longer in premature infants. Except for a slight loss of appetite, there are no other clinical symptoms. If jaundice occurs 24 hours after birth, the daily serum bilirubin rises more than 5 mg / dl or >0.5 mg / dl per hour; the duration is long, full-term infants > 2 weeks, premature infants > 4 weeks and still persist, even If the jaundice continues to deepen or aggravates or reappears after subs...

Claims

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