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High-fidelity belly deformation mold for verifying precision of deformable registration algorithm and preparing method thereof

A technology of accuracy verification and registration algorithm, which is applied in the direction of educational appliances, teaching models, instruments, etc., can solve the problems of single organ, lack of three-dimensional anatomical structure, and complexity of deformation of three-dimensional structure without three-dimensional anatomical structure, and achieve uniform distribution , the effect of improving the accuracy

Inactive Publication Date: 2016-03-09
SOUTHERN MEDICAL UNIVERSITY
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Problems solved by technology

[0004] At present, most phantoms are two-dimensional structures, which do not have the complexity of the three-dimensional anatomical structure of real organs and the deformation of three-dimensional structures
Although there are also some phantoms with three-dimensional structures, the organs formed by them are single and do not have the three-dimensional anatomical structure of real organs. The deformation is too simple, such as rotation or translation, and few phantoms can verify the deformation registration algorithm and verification. Dose stacking precision combined with

Method used

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  • High-fidelity belly deformation mold for verifying precision of deformable registration algorithm and preparing method thereof
  • High-fidelity belly deformation mold for verifying precision of deformable registration algorithm and preparing method thereof
  • High-fidelity belly deformation mold for verifying precision of deformable registration algorithm and preparing method thereof

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preparation example Construction

[0036] A method for preparing a highly simulated abdominal deformation phantom for verification of the accuracy of deformation registration algorithms, comprising the following steps:

[0037] 1) Adjust the mixing ratio of PVC resin powder-plasticizer, prepare PVC plastic samples with different mixing ratios, carry out CT scanning to each PVC plastic sample, measure the CT value, and draw the relationship diagram between the mixing ratio and the CT value;

[0038] 2) Using the CT image of an abdominal tumor patient as a template, outline the contour lines of the liver, spleen, kidney, stomach and tumor, draw a three-dimensional mold map at a ratio of 1:1, and obtain a model that is highly similar to the outline of human organs through 3D printing 3D mold;

[0039] 3) Set marking points in the three-dimensional mold in step 2), select the corresponding PVC polymerization solution according to the CT value of each organ, and inject and mold it to obtain the simulated organ;

[00...

Embodiment

[0053] A method for preparing a highly simulated abdominal deformation phantom for verification of the accuracy of deformation registration algorithms, comprising the following steps:

[0054] 1) Adjust the mixing ratio of PVC resin powder (S-65)-plasticizer (dioctyl terephthalate) to make 16 pieces of PVC plastics with different mixing ratios, the range of mixing ratio is 8×10 -2 g / mL~23×10 -2 g / mL, in intervals of 1×10 -2 g / mL change, CT scanning was performed on 16 PVC plastic samples, the average CT value of each PVC plastic sample was measured, and the data was recorded;

[0055] 2) With the mixing ratio of PVC resin powder-plasticizer (10 -2 g / mL) is the abscissa, and the CT value (HU) is the ordinate, draw the relationship between the mixing ratio and the CT value (such as figure 1 shown);

[0056] 3) Using the CT image of an abdominal tumor patient as a template, outline the contour lines of the liver, spleen, kidney, stomach and tumor, and then export the mask ima...

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Abstract

The invention discloses a high-fidelity belly deformation mold for verifying precision of a deformable registration algorithm and a preparing method thereof. The preparing method for the high-fidelity belly deformation mold comprises the following steps of 1), preparing a three-dimensional mold which has high similarity to the outer contour of human body belly organs according to a computed tomography (CT) image of a belly tumor patient; 2) preparing simulated organs with CT numbers which approach the CT numbers of the organs; 3) preparing a simulated rigid bone; and 4) preparing a belly outer contour mold, placing the simulated organs and the simulated rigid bone into the mold, injecting PVC polymerization solution for performing injection molding, and arranging marking points and thermoluminescence agent films. The main organs in the mold have CT numbers which are similar with the CT number of human body organs and can simulate deformation of belly organs in a relatively real manner. Through arranging marking points and the thermoluminescence agent films in organs and portions among the organs, geometrical precision verification of the deformable registration algorithm and agent superposing precision verification in adaptive radiotherapy can be performed. High mold resilience and high reproducibility after deformation are realized.

Description

technical field [0001] The invention relates to a high-simulation abdominal deformation phantom used for verification of deformation registration algorithm accuracy and a preparation method thereof. Background technique [0002] Accurate image deformation registration technology is one of the key technologies in image-guided radiation therapy (IGRT), and image guidance at any level is based on the results of medical image registration. In multi-fraction treatment, the deformation of the patient's internal organs and tissue, as the tumor volume shrinks with the progress of radiotherapy, etc., will cause setup errors. The image registration technology can correct the set-up error based on the images obtained for each fractional treatment, correct the radiotherapy plan, and realize adaptive radiotherapy. In addition, the image deformation registration technology can also be used for the deformation and accumulation of multi-fraction radiotherapy doses. It can compare the cumul...

Claims

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Application Information

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IPC IPC(8): G09B23/30
CPCG09B23/30
Inventor 甄鑫廖煜良周凌宏陈海斌
Owner SOUTHERN MEDICAL UNIVERSITY
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