Brefeldin A combined anti-cancer compound medicine
A technology of brefeldin and feldspar, applied in the field of anti-cancer compound drugs combined with brefeldin A, can solve the problems of large economic burden for patients, immature technology, complicated preparation methods, etc., and achieve relief Economic burden, reduction of human injury, reduction of toxic and side effects
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[0022] Docetaxel (Docetaxol (DTC)) or Brefeldin A ((+)-Brefeldin A (BFA)) or docetaxel (DTC) and Brefeldin A (BFA) alone are given below. ) were used in combination to study the growth and apoptosis of human prostate cancer cells PC-3 (androgen-independent).
[0023] In the initial research of the technical solution provided by the invention, we screened the effect of a certain number of compounds and different doses of the corresponding compounds on the human prostate cancer cell PC-3 (androgen-independent), and found that docetaxel (DCT) in its Different doses administered alone have different degrees of inhibition of growth and induction of apoptosis on prostate cancer cells PC-3 ( figure 1 ). Brefeldin A (BFA) has a strong inhibitory growth-inducing apoptosis effect on prostate cancer cell PC-3 at different doses administered alone ( figure 2 ).
[0024] In the comparative experiment of in-depth study of drug combination application, the single dose of docetaxel, the s...
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