Medicinal composition for treating medical diseases and preparation method thereof
A composition and drug technology, applied in the directions of drug combination, metabolic diseases, pharmaceutical formulations, etc., can solve the problem that the effect is not very significant, and achieve the effects of better drug treatment effect, high marked efficiency and convenient taking.
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Embodiment 1
[0036] The pharmaceutical composition of Example 1 of the present invention consists of the following preparation raw materials in parts by weight: 10 parts of Ophiopogon japonicus, 10 parts of Artemisia argyi, 8 parts of Rehmannia glutinosa, 8 parts of safflower, 6 parts of Chuanxiong, 6 parts of dodder, 4 parts of Angelica dahurica, motherwort 4 parts, Poria cocos 6 parts, angelica 6 parts and licorice 4 parts.
[0037] The preparation method is as follows:
[0038] S1: Weigh Ophiopogon japonicus, Artemisia argyi, Rehmannia glutinosa, Safflower, Rhizoma Chuanxiong, Cuscuta, Angelica dahurica, Motherwort, Poria cocos, Angelica, and licorice, crush them separately, and set aside;
[0039] S2: Add all medicinal materials into purified water 10 times the weight of the original medicinal materials, soak for 24 hours, decoct for 3 hours, filter; then add purified water 8 times the weight of the initial weight, decoct for 3 hours, filter and retain the filter residue, combine the f...
Embodiment 2
[0044] The pharmaceutical composition of Example 2 of the present invention is composed of the following preparation raw materials in parts by weight: 20 parts of Ophiopogon japonicus, 22 parts of Artemisia argyi, 20 parts of Rehmannia glutinosa, 16 parts of safflower, 18 parts of Chuanxiong, 18 parts of dodder seed, 16 parts of Angelica dahurica, motherwort 14 parts, 14 parts of Poria cocos, 12 parts of angelica and 8 parts of licorice.
[0045] The preparation method is the same as in Example 1.
Embodiment 3
[0047]The pharmaceutical composition of Example 3 of the present invention is composed of the following preparation raw materials in parts by weight: 15 parts of Ophiopogon japonicus, 16 parts of Artemisia argyi, 14 parts of Rehmannia glutinosa, 12 parts of safflower, 12 parts of Chuanxiong, 12 parts of Cuscuta, 10 parts of Angelica dahurica, motherwort 8 parts, 10 parts of Poria cocos, 9 parts of angelica and 6 parts of licorice.
[0048] The preparation method is the same as in Example 1.
[0049] The therapeutic effect of the pharmaceutical composition of the present invention on the rat model of diabetic nephropathy
[0050] 1. Prepare the model
[0051] Select 40 healthy male adult Wistar rats, weighing 220g-260g, and feed them with high-fat feed, with unlimited water intake. Rats were intraperitoneally injected with streptozotocin after unilateral renal ligation. Before the operation, the rats were fasted for 12 hours and injected with pentobarbital sodium solution ...
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