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Medicinal composition for treating medical diseases and preparation method thereof

A composition and drug technology, applied in the directions of drug combination, metabolic diseases, pharmaceutical formulations, etc., can solve the problem that the effect is not very significant, and achieve the effects of better drug treatment effect, high marked efficiency and convenient taking.

Inactive Publication Date: 2016-04-06
GUANGDONG JUZHICHENG TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The pharmaceutical composition has the effects of nourishing qi and nourishing yin, clearing away heat and dampness, promoting blood circulation and dredging collaterals, but the effect of the pharmaceutical composition on lowering blood sugar, invigorating the kidney and invigorating the spleen is not very significant

Method used

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  • Medicinal composition for treating medical diseases and preparation method thereof
  • Medicinal composition for treating medical diseases and preparation method thereof
  • Medicinal composition for treating medical diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] The pharmaceutical composition of Example 1 of the present invention consists of the following preparation raw materials in parts by weight: 10 parts of Ophiopogon japonicus, 10 parts of Artemisia argyi, 8 parts of Rehmannia glutinosa, 8 parts of safflower, 6 parts of Chuanxiong, 6 parts of dodder, 4 parts of Angelica dahurica, motherwort 4 parts, Poria cocos 6 parts, angelica 6 parts and licorice 4 parts.

[0037] The preparation method is as follows:

[0038] S1: Weigh Ophiopogon japonicus, Artemisia argyi, Rehmannia glutinosa, Safflower, Rhizoma Chuanxiong, Cuscuta, Angelica dahurica, Motherwort, Poria cocos, Angelica, and licorice, crush them separately, and set aside;

[0039] S2: Add all medicinal materials into purified water 10 times the weight of the original medicinal materials, soak for 24 hours, decoct for 3 hours, filter; then add purified water 8 times the weight of the initial weight, decoct for 3 hours, filter and retain the filter residue, combine the f...

Embodiment 2

[0044] The pharmaceutical composition of Example 2 of the present invention is composed of the following preparation raw materials in parts by weight: 20 parts of Ophiopogon japonicus, 22 parts of Artemisia argyi, 20 parts of Rehmannia glutinosa, 16 parts of safflower, 18 parts of Chuanxiong, 18 parts of dodder seed, 16 parts of Angelica dahurica, motherwort 14 parts, 14 parts of Poria cocos, 12 parts of angelica and 8 parts of licorice.

[0045] The preparation method is the same as in Example 1.

Embodiment 3

[0047]The pharmaceutical composition of Example 3 of the present invention is composed of the following preparation raw materials in parts by weight: 15 parts of Ophiopogon japonicus, 16 parts of Artemisia argyi, 14 parts of Rehmannia glutinosa, 12 parts of safflower, 12 parts of Chuanxiong, 12 parts of Cuscuta, 10 parts of Angelica dahurica, motherwort 8 parts, 10 parts of Poria cocos, 9 parts of angelica and 6 parts of licorice.

[0048] The preparation method is the same as in Example 1.

[0049] The therapeutic effect of the pharmaceutical composition of the present invention on the rat model of diabetic nephropathy

[0050] 1. Prepare the model

[0051] Select 40 healthy male adult Wistar rats, weighing 220g-260g, and feed them with high-fat feed, with unlimited water intake. Rats were intraperitoneally injected with streptozotocin after unilateral renal ligation. Before the operation, the rats were fasted for 12 hours and injected with pentobarbital sodium solution ...

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PUM

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Abstract

The invention belongs to the field of traditional Chinese medicine and relates to a medicinal composition for treating medical diseases and a preparation method thereof. The medicinal composition consists of the following raw materials in parts by weight: 10-20 parts of radix ophiopogonis, 10-22 parts of folium artemisiae argyi, 8-20 parts of radix rehmanniae praeparata, 8-16 parts of safflower, 6-18 parts of rhizoma ligustici chuanxiong, 6-18 parts of cuscuta chinensis, 4-16 parts of radix angelicae, 4-14 parts of herba leonuri, 6-14 parts of poria cocos, 6-12 parts of Chinese angelica and 4-8 parts of liquorice. The medicine provided by the invention has the advantages of reasonable formula and strong synergistic effect and is used as the medicine compatibility for treating medical diseases; and according to clinical verification, a very remarkable effect is achieved.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating internal diseases and a preparation method thereof. Background technique [0002] Diabetic nephropathy is the most serious and harmful chronic complication caused by diabetes. It is one of the manifestations of systemic microangiopathy in diabetes. The clinical features are proteinuria, progressive renal damage, hypertension, edema, and severe renal function in the late stage. Failure is one of the leading causes of death in diabetic patients. [0003] In Chinese medical literature, diabetic nephropathy is not only diabetes, but also belongs to the category of edema, urine turbidity, fullness, and other diseases in the category of kidney disease. The pathogenesis is mainly kidney deficiency. Unfavorable qi transformation, internal stagnation of water and dampness, and even turbidity and poison accumulation, deficiency and decl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P3/10A61P13/12
CPCA61K36/8968A61K36/076A61K36/232A61K36/236A61K36/282A61K36/286A61K36/39A61K36/484A61K36/533A61K36/804A61K2236/331A61K2236/333A61K2236/39A61K2236/51
Inventor 邓凤桂
Owner GUANGDONG JUZHICHENG TECH
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