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Pharmaceutical preparation for treating low blocking antibody type recurrent spontaneous abortions

A technology for recurrent miscarriage and pharmaceutical preparations, applied in the field of traditional Chinese medicine, to achieve the effects of promoting tumor metastasis, rigorous and reasonable prescriptions, and wide drug sources

Inactive Publication Date: 2016-06-22
张艳娟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The inventor is good at combining modern medical theory with traditional medical theory, and combining syndrome differentiation and disease differentiation, aiming at the etiology and pathogenesis of recurrent miscarriage with low antibodies. Insufficient, providing a pharmaceutical preparation for treating recurrent miscarriage with low blocking antibody

Method used

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  • Pharmaceutical preparation for treating low blocking antibody type recurrent spontaneous abortions
  • Pharmaceutical preparation for treating low blocking antibody type recurrent spontaneous abortions
  • Pharmaceutical preparation for treating low blocking antibody type recurrent spontaneous abortions

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1 capsule

[0038] Prescription: 12 parts of psoralen, 18 parts of dodder, 10 parts of scull, 25 parts of double ginseng, 10 parts of red nangen, 10 parts of Atractylodes macrocephala, 15 parts of codonopsis, 3 parts of Schisandra, 10 parts of angelica, and 12 parts of Lao Lai Qing.

[0039] Preparation method: (1) Take Chinan root, Angelica sinensis, and Laolaiqing according to the prescription, add 6 times the amount of 65% ethanol, reflux extraction twice, each time for 2 hours, filter, combine the two filtrates, and recover ethanol under reduced pressure until no alcohol taste, continue to decompress and concentrate into a dry extract, freeze-dry, and pulverize to obtain an ethanol extract;

[0040] (2) Combine the filter residue after ethanol extraction of Chinangen, Angelica, and Laolaiqing with Psoralen, Dodder, Scull, Shuangshen, Atractylodes Rhizoma, Codonopsis, and Schisandra, add 8 times the amount of water, decoct and extract twice, each After 1-...

Embodiment 2

[0042] Embodiment 2 capsules

[0043] Prescription: 10 parts of psoralen, 15 parts of dodder, 12 parts of scorpion, 28 parts of double ginseng, 8 parts of red root, 12 parts of Atractylodes macrocephala, 10 parts of codonopsis, 2 parts of Schisandra, 12 parts of angelica, and 10 parts of laoliqing.

[0044] Preparation method: (1) Take Chinan root, Angelica sinensis, and Laolaiqing according to the prescription, add 5 times the amount of 65% ethanol, reflux extraction twice, each time for 1 to 3 hours, filter, combine the two filtrates, and recover the ethanol under reduced pressure to No alcohol smell, continue to concentrate under reduced pressure to obtain a dry extract, freeze-dry, and pulverize to obtain an ethanol extract;

[0045] (2) Combine the filter residue after ethanol extraction of Chinangen, Angelica, and Laolaiqing with Psoralen, Dodder, Scull, Shuangshen, Atractylodes Rhizoma, Codonopsis, and Schisandra, add 6 times the amount of water, decoct and extract 3 ti...

Embodiment 3

[0047] Embodiment 3 capsules

[0048] Prescription: 10 parts of psoralen, 15 parts of dodder, 15 parts of scorpion, 30 parts of double ginseng, 12 parts of red nan root, 8 parts of Atractylodes macrocephala, 12 parts of codonopsis, 1.5 parts of schisandra, 8 parts of angelica, and 15 parts of laoliqing.

[0049] Preparation method: (1) Take Chinan root, Angelica sinensis and Laolaiqing according to the prescription, add 8 times the amount of 65% ethanol, reflux extraction twice, each time for 1 to 3 hours, filter, combine the two filtrates, and recover the ethanol under reduced pressure to No alcohol smell, continue to concentrate under reduced pressure to obtain a dry extract, freeze-dry, and pulverize to obtain an ethanol extract;

[0050] (2) Combine the filter residue after ethanol extraction of Chinangen, Angelica, and Laolaiqing with Psoralen, Dodder, Scull, Shuangshen, Atractylodes Rhizoma, Codonopsis, and Schisandra, add 8 times the amount of water, decoct and extract ...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine and relates to a pharmaceutical preparation for treating low blocking antibody type recurrent spontaneous abortions and a preparation method thereof. The pharmaceutical preparation is elaborately prepared from fructus psoraleae, semen cuscutae, textile screw pine seeds, roots of lagerflower triplostegia, roots of gurgeon stopper, rhizoma atractylodis macrocephalae, radix codonopsis, fruits of Chinese magnoliavine, radix angelica sinensis and roots of boerhaavia diffusa according to a certain weight ratio. All the medicinal materials are under compatibility to achieve the effects of tonifying the spleen and kidney, nourishing and activating blood, regulating immunity, promoting increase of blocking antibodies and relieving spleen and kidney depletion, blood stasis and other symptoms, and therefore the treatment effect is achieved.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and relates to a pharmaceutical preparation for treating recurrent abortion with low blocking antibody type and a preparation method thereof. Background technique [0002] Recurrent spontaneous abortion (recurrent spontaneous abortion, RSA) refers to two or more consecutive spontaneous abortions, the etiology of which is complex, in addition to genetic, anatomical, infection, endocrine and other factors, about 40% to 65% are related to immune factors. About 2 / 3 of recurrent spontaneous abortions caused by immune factors show the lack of blocking antibody (BA). BA is a protective antibody produced by the mother after pregnancy that protects the fetus from attack by the mother's immune system. [0003] Modern medicine often adopts partner lymphocyte in vitro induction immunotherapy for active immunotherapy for RSA caused by BA deficiency. Risk factors, while passive immunothe...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61P15/06
CPCA61K36/185A61K36/232A61K36/284A61K36/344A61K36/39A61K36/487A61K36/57A61K36/61A61K36/79A61K36/88A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K2300/00
Inventor 张艳娟
Owner 张艳娟
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