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Drug composition for treating animal acariasises and preparation method and application thereof

A composition and drug technology, applied in the direction of drug combination, pharmaceutical formula, drug delivery, etc., can solve problems such as restricting the healthy development of animal husbandry and economic benefits, affecting animal production performance and economic value, drug residues, etc., to avoid drug resistance Medicinal properties, enhanced absorption and skin penetration, and less residue effects

Active Publication Date: 2016-07-06
LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main manifestations of this disease in animals are decreased appetite or extinction, emaciation, hair loss, etc., which seriously affects the production performance and economic value of animals, and seriously restricts the healthy development and economic benefits of animal husbandry.
At present, the drugs used to treat animal mites are mainly chemically synthesized and antibiotic drugs, such as ivermectin, mite net, etc. While these drugs can effectively prevent and treat animal mites, they have caused public health problems due to drug residues. , food safety and ecological environment

Method used

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  • Drug composition for treating animal acariasises and preparation method and application thereof
  • Drug composition for treating animal acariasises and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The preparation of pharmaceutical composition of the present invention is as follows:

[0021] Mix 167μL eugenol, 666μL thymol, and 167μL carvacrol, dissolve in 8ml of ethanol, add 28ml of propylene glycol, 8ml of glycerin formal, 8ml of dimethyl sulfoxide, and 0.8ml of azone, mix well, and then slowly add Add water to 100ml, set to volume, stir and grind while adding to make it uniform, and then the emulsion is obtained.

Embodiment 2

[0023] The preparation of pharmaceutical composition of the present invention is as follows:

[0024] Mix 167μL eugenol, 666μL thymol, and 167μL carvacrol, dissolve in 10ml of ethanol, add 25ml of propylene glycol, 10ml of glycerin formal, 5ml of dimethyl sulfoxide, and 0.5ml of azone, mix well, and then slowly add Add water to 100ml, set to volume, stir and grind while adding to make it uniform, and then the emulsion is obtained.

Embodiment 3

[0026] The preparation of pharmaceutical composition of the present invention is as follows:

[0027] Mix 1.67mL eugenol, 6.66mL thymol, and 1.67mL carvacrol, dissolve in 50ml of ethanol, add 300ml of propylene glycol, 50ml of glycerin formal, 100ml of dimethyl sulfoxide, and 10ml of azone, mix well, and then Slowly add water to 1000ml, set to volume, stir and grind while adding to make it uniform, and then the emulsion is obtained.

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PUM

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Abstract

The invention provides a drug composition for treating animal acariasises.The drug composition is prepared from eugenol, thymol and carvacrol.The invention further provides a preparation method of the drug composition and application of the drug composition in the preparation of drugs for treating the animal acariasises.The drug composition has the advantages of being safe, effective, low in toxicity, free of pollution and the like on the aspect of the treatment of the animal acariasises.The residues of the drug composition in use are few, a preparation process is simple, the cost is low, various preparations are convenient to prepare, the drug composition is convenient to use and can be directly applied to affected parts.The cure rate is as high as 85%, and the effective rate is up to 95% or above.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a medicine composition for treating acariasis in animals, a preparation method and application thereof. Background technique [0002] Animal acariasis is a chronic ectoparasitic disease of animals caused by mite parasites on the surface. Its pathogens are sarcoptic mites and itchy mites, which mainly occur in late autumn, winter and early spring, through direct or indirect contact between sick animals and healthy animals Infection occurs widely in cattle, sheep, horses, dogs, rabbits, chickens and other animals, and can also be transmitted to humans. The infection and morbidity rates are higher in pastoral areas, farming and pastoral areas, and large-scale farms. The main manifestations of this disease in animals are loss of appetite or waste, emaciation, hair loss, etc., which seriously affects the production performance and economic value of animals, and seriously...

Claims

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Application Information

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IPC IPC(8): A61K31/085A61P33/14A61K31/05
CPCA61K9/0014A61K9/107A61K31/05A61K31/085A61K47/10A61K47/16A61K47/20A61K47/22A61K2300/00
Inventor 尚小飞苗小楼王东升王瑜张继瑜潘虎
Owner LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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