Cycloastragenol extract and preparation method and application thereof

A technology of cycloastragenol and extract, which is applied in the field of medicine, can solve the problems of very few studies on cycloastragenol extract, and achieve the effects of slowing down aging damage, improving cell vitality, and anti-aging activity
CN106083979AInactive Publication Date: 2016-11-09ZHEJIANG UNIV OF TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ZHEJIANG UNIV OF TECH
Publication Date
2016-11-09
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a cycloastragenol extract. A preparation method of the cycloastragenol extract comprises the steps that coarse astragalus membranaceus powder is extracted by using an alkaline alcohol water solution with a pH value of 11-13 to obtain a coarse astragaloside extract; the obtained coarse astragaloside extract is enriched and purified through macroporous resin to obtain an astragaloside extract; the obtained astragaloside extract is subjected to Smith degradation to obtain the cycloastragenol extract. For cycloastragenol extract preparation, an optimum extraction method is obtained through multiple times of tests conducted on the pH value, sodium periodate dosage and methanol concentration in the extraction conditions. The method is good in reproducibility, simple and easy to operate. The prepared cycloastragenol extract can obviously retard senility hurt of H2O2 to PC12 cells, and improve cell vitality, and the cycloastragenol extract obtained by adopting the preparation method has certain anti-aging activity and can be applied to preparation of anti-aging medicines and health-care products.
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Description

(1) Technical field

[0001] The invention relates to a cycloastragenol extract, a preparation method and application of the extract, and belongs to the field of medicine. (2) Background technology

[0002] At present, the aging population of countries around the world is accelerating. According to statistics, in 2012, the elderly population aged 65 and above in my country accounted for 9.4% of the total population. Double the number of elderly people in 2012. In such a severe situation, human beings are facing enormous challenges. Aging and anti-aging have become a hot topic in medical discussion today. With the improvement of people's living standards and the continuous strengthening of the concept of returning to green life, how to effectively prevent aging and improve the quality of life has become an urgent problem that people need to solve. Therefore, people's demand for anti-aging related green health care products and plant extracts continues to increase.

[0003] In...

Claims

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