Compound extract of rhizoma polygonati and Chinese wolfberry fruits, as well as preparation method and application thereof

A wolfberry extract and extract technology, which is applied in the compound extract of Rhizoma Polygonatum and Lycium barbarum and its preparation and application fields, can solve the problems of not mentioning the effect of mitochondrial activity, not mentioning the compatible use and compatibility ratio of Rhizoma Polygonatum and Lycium barbarum

Active Publication Date: 2016-11-16
SHANGHAI JAHWA UNITED +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above-mentioned patents relate to the skin-related beauty effects of wolfberry or sealwort, they do not mention the

Method used

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  • Compound extract of rhizoma polygonati and Chinese wolfberry fruits, as well as preparation method and application thereof
  • Compound extract of rhizoma polygonati and Chinese wolfberry fruits, as well as preparation method and application thereof
  • Compound extract of rhizoma polygonati and Chinese wolfberry fruits, as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] Embodiment 1: the preparation of Polygonatum Lycium barbarum extract

[0053] Polygonatum: Lycium barbarum (1:1) → 10 times deionized water decoction extraction → filtration → filtrate, using 200nm ceramic membrane for membrane separation → decoction and concentration of dialysate, namely Polygonatum Lycium barbarum compound extract 1, crude drug concentration 0.69g / g , solid content 19.58%.

Embodiment 2

[0054] Embodiment 2: the preparation of Polygonatum Lycium barbarum extract

[0055] Polygonatum: Lycium barbarum (1:1) → 10 times 70% ethanol immersion extraction → filtration → filtrate concentrated under reduced pressure, namely Polygonatum Lycium barbarum compound extract 2, crude drug concentration 0.56g / g, solid content 15.04%.

Embodiment 3

[0056] Embodiment 3: the preparation of sealwort wolfberry extract

[0057] Polygonatum: Lycium barbarum (1:1) → 10 times deionized water decoction and extraction → filtration → filtrate concentrated to 1 times the crude drug amount → 70% ethanol alcohol precipitation → filtration → filtrate concentrated under reduced pressure to obtain Polygonatum Lycium barbarum compound extract 3, The crude drug concentration is 1.0g / g, and the solid content is 24.74%.

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Abstract

The invention discloses a compound extract of rhizoma polygonati and Chinese wolfberry fruits, as well as a preparation method and application thereof. The compound extract is prepared from rhizoma polygonati and Chinese wolfberry fruit extract, wherein the weight ratio of rhizoma polygonati to Chinese wolfberry fruit raw materials is 1:5-5:1, and the crude herbal concentration of the extract is 0.1mg/mL-5mg/mL. The compound extract can be used for enhancing expression of peroxire-doxin in cells and/or ROS content in fibroblasts after UVA radiation and increasing the mitochondria activity of epidermal keratinocytes and/or the content of adenosine triphosphate in the epidermal keratinocytes. The compound extract is added into a skin externally applied preparation as a functional additive for skin care.

Description

technical field [0001] The invention relates to a compound extract of traditional Chinese medicine, especially a compound extract of Rhizoma Polygonati Lycium barbarum and its preparation method and application, which can enhance the mitochondrial activity of skin cells, especially epidermal cells, and / or increase the content of adenosine triphosphate (ATP) in epidermal cells, and can enhance intracellular The expression of antioxidant proteins and / or the reduction of ROS content in fibroblasts after UVA radiation can be used as functional additives in skin external preparations for skin care. Background technique [0002] Consisting of the epidermis, dermis and subcutaneous tissue, the skin is the largest organ of the human body. The skin covers the whole body and is a natural barrier to protect the human body. It can not only protect various tissues and organs in the human body from external substances such as pathogenic microorganisms and physical and other mechanical dam...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61K36/8969A61Q19/08A61Q17/04A61P17/18A61P17/00
CPCA61K36/8969A61Q17/04A61Q19/08A61K8/97A61K9/0014A61K36/815A61K2800/10A61K2300/00
Inventor 祝乐韩乐孙懿赵亚陈默冯冰施镇
Owner SHANGHAI JAHWA UNITED
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