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Preparation method of amomum tsao-ko volatile oil vomiting-alleviating spraying agent

A technology of volatile oil and spray, which is applied in the field of preparation of Caoguo volatile oil antiemetic spray, which can solve the problems of unsatisfactory antiemetic effect of antiemetic drugs and human side effects, etc., achieve good antiemetic effect, promote sweating, and have no pollution to the environment Effect

Inactive Publication Date: 2016-12-14
GUANGXI BOTANICAL GARDEN OF MEDICINAL PLANTS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Existing antiemetic drugs have unsatisfactory antiemetic effects, and most of them are obtained by chemical synthesis. In addition to the active ingredients, they also contain other chemical additives, which have certain side effects on the human body and are not suitable for certain groups of people. For example, they are not suitable for vomiting caused by pregnant women

Method used

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Examples

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Comparison scheme
Effect test

example 1

[0029] A preparation method of Caoguo volatile oil antiemetic spray, comprising the following steps:

[0030] Step 1. Soak the grass fruit in a starch solution with a concentration ratio of 1% by mass for 2 hours, then soak it in clean water for 30 minutes, freeze-dry the grass fruit soaked in clean water and crush to obtain the grass fruit freeze-dried powder, and make the grass fruit jelly After passing through a 40-mesh sieve, the dry powder is put into the extraction kettle of a supercritical carbon dioxide extraction device. After extraction for 90 minutes under the conditions of extraction temperature of 45°C, extraction pressure of 18MPa, and carbon dioxide flow rate of 88L / h, the extract is released from the separation kettle , to obtain Tsaoguo volatile oil;

[0031] Step 2. Wash the ginger and cut it into slices of 2 cm in thickness. Soak the slices in culture solutions with initial concentrations of 800 CFU / ml and 300 CFU / ml of Citrobacter fischeri and Lactobacillus...

example 2

[0036] A preparation method of Caoguo volatile oil antiemetic spray, comprising the following steps:

[0037] Step 1. Soak the grass fruit in a starch solution with a mass percentage concentration of 1% for 2 hours, then soak it in clear water for 30 minutes, freeze-dry the grass fruit soaked in clear water and crush to obtain the grass fruit freeze-dried powder, and pass the grass fruit freeze-dried powder 40 mesh sieve, put grass fruit powder and entrainer together into the extraction kettle of supercritical carbon dioxide extraction device, the entrainer used is a mixed solution of methanol and ethanol with a mass ratio of 1:1, at an extraction temperature of 45°C, extract After extracting for 90 minutes under the conditions of a pressure of 18MPa and a carbon dioxide flow rate of 88L / h, the tsaoko volatile oil extract was released from the separation kettle, and the obtained tsaoko volatile oil extract was placed under the conditions of a vacuum of 40KPa and a distillation ...

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Abstract

The invention discloses a preparation method of an amomum tsao-ko volatile oil vomiting-alleviating spraying agent, and the method comprises the following steps: 1, using a supercritical carbon dioxide extraction device for extraction to obtain amomum tsao-ko volatile oil; 2, using the supercritical carbon dioxide extraction device for extraction to obtain raw ginger essential oil; 3, using the supercritical carbon dioxide extraction device for extraction to obtain citrus essential oil; 4, using the supercritical carbon dioxide extraction device for extraction to obtain mint essential oil; and 5, mixing 40-60 parts by weight of the amomum tsao-ko volatile oil, 8-15 parts by weight of the raw ginger essential oil, 1-3 parts by weight of the citrus essential oil, 1-3 parts by weight of the mint essential oil and 50-100 parts by weight of vegetable oil in ratio, filtering the mixed solution to obtain the amomum tsao-ko volatile oil vomiting-alleviating spraying agent. The amomum tsao-ko volatile oil vomiting-alleviating spraying agent has good vomiting-alleviating effect and sweet smell, does not contain other additives, has no side effects on the human body, and is suitable for all people, including pregnant women to use.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine antiemetic spray. More specifically, the present invention relates to a preparation method of Caoguo volatile oil antiemetic spray. Background technique [0002] Vomiting refers to a disease in which the stomach loses its balance and descends, and the qi goes against the top, forcing the contents of the stomach to spit out from the mouth. Clinically, it is called vomiting when there is something and sound, vomiting when there is something without sound, and retching when there is no sound. Clinical vomiting and vomiting often occur at the same time, so they are collectively called vomiting. Medicines to prevent or relieve nausea and vomiting. Existing antiemetic drugs inhibit the vomiting response through different links, including the following categories: thiazide drugs, such as chlorpromazine, promethazine, perphenazine, trifluoperazine, etc., mainly inhibit the emetic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/12A61P1/08C11B9/02
Inventor 缪剑华莫单丹唐炳兰周小雷王硕龚小妹候小莉欧春丽
Owner GUANGXI BOTANICAL GARDEN OF MEDICINAL PLANTS
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