Iodophor disinfectant

Abstract

The invention relates to an iodophor disinfectant. When a solution with the effective iodine concentration of 250 mg / L acts on staphylococcus aureus and pseudomonas aeruginosa for 2 min, the average killing logarithm value is larger than 5.00; when a solution with the effective iodine concentration of 500 mg / L acts on candida albicans for 2 min, the average killing logarithm value is larger than 5.00; the bactericidal effect is achieved; the killing effect on natural bacteria on the skin surface is achieved when a solution with the effective iodine concentration of 500 mg / L acts for 2 min. The iodophor disinfectant has a high killing effect on the staphylococcus aureus, the pseudomonas aeruginosa and the candida albicans and is inirritative to skin, damaged skin and animal eyes, capable of rapidly achieving the bactericidal effect, high in skin permeability, lasting in sterilization, easy to use, unnecessary in deiodination and stable in character.

Description

technical field [0001] The invention relates to a disinfectant, in particular to an iodophor disinfectant, which belongs to the field of medical disinfection. Background technique [0002] Iodophor is an indeterminate complex formed by iodine and a surfactant. The surfactant is the carrier and solubilizer of iodine, and the iodine element exists in the carrier in the form of complexation or inclusion. In water, iodine slowly dissociates to produce a bactericidal effect. [0003] Since the second half of the 19th century, many people have highly evaluated the effectiveness of iodine as an antibacterial agent. The non-metal element iodine named by Gay-lussac in 1814 was discovered by French scientist Courtors in 1812. There is no iodine in a free state in nature, and most of the iodide or other compounds of iodine are found. The latter is abundant in seaweed ash, oil well brine and iodine nitrate in Chile. The first dedicated reference to the use of iodine in wounds was pub...

AI Technical Summary

Problems solved by technology

However, iodophor mainly uses surfactants as carriers and has the following classifications: (1) non-ionic surface active iodine such as polyvinylpyrrolidone iodine (PVP-I), nonylphenol polyoxyethylene ether iodine (POP-I) polyethylene glycol Alcohol iodine (PEG-I), polyvinyl alcohol iodine (PVP-I), polyalcohol ether iodine (NP-I), etc. Among them, polyvinylpyrrolidone iodine (PVP-I) has been included in the Chinese Pharmacopoeia, and the carrier of most iodophor preparations is usually Non-ionic surfactants, the nature of this type of iodophor is undetermined, but it is rarely used. Anionic surface active iodine, such as alkyl iodide salt complexed iodine, has poor stability, but has a good decontamination effect. The bactericidal mechanism of iodophor is generally considered Based on its iodination and damage to the outer layer of cells, free iodine can directly interact with bacterial proteins and bacterial enzyme proteins to undergo halogenation, destroying the biological activity of proteins and leading to the death of microorganisms

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