Diabetic nephropathy treating pharmaceutical composition, preparation method and uses thereof

A technology for diabetic nephropathy and a composition is applied in the field of pharmaceutical compositions for the treatment of diabetic nephropathy and achieves the effect of good clinical application prospects

Active Publication Date: 2017-02-15
陈明 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Irbesartan is a commonly used drug in the treatment of diabetes and its efficacy is good, but there are indigestion, heartburn, diarrhea, musculoskeletal pain, fatigue and upper respiratory tract infection, anxiety, nervousness, chest pain, pharyngitis, nausea and vomiting, rash, heartbeat Side effects such as speed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The preparation of embodiment 1 pharmaceutical composition of the present invention

[0027] 1. Raw materials

[0028] Astragalus 30g, kudzu root 30g, golden cherry seed 20g, gorgon fruit 20g, ghost arrow feather 15g, dodder seed 10g, coptis 10g, wine rhubarb 6g, yam 15g, leech 9g.

[0029] 2. Preparation method

[0030] Take the raw material, decoct 3 times with 20 times of water, 45 minutes each time, combine the filtrate, concentrate to a relative density of about 1.4, add dextrin and other auxiliary materials, dry, powder, and granulate.

Embodiment 2

[0031] The preparation of embodiment 2 pharmaceutical composition of the present invention

[0032] 1. Raw materials

[0033] 24 parts of astragalus, 24 parts of kudzu root, 16 parts of golden cherry, 16 parts of gorgon, 12 parts of ghost arrow feather, 8 parts of dodder, 8 parts of berberine, 5 parts of rhubarb, 12 parts of yam, and 7 parts of leeches.

[0034] 2. Preparation method

[0035] Decoct with 8-10 times water for 3 times, 45 minutes each time, combine the filtrate, concentrate to the specified amount, centrifuge, and pack.

Embodiment 3

[0036] The preparation of embodiment 3 pharmaceutical composition of the present invention

[0037] 1. Raw materials

[0038] 36 parts of astragalus, 36 parts of kudzu root, 24 parts of golden cherry, 24 parts of gorgon, 18 parts of ghost arrow feather, 12 parts of dodder, 12 parts of berberine, 7 parts of rhubarb, 18 parts of yam, and 11 parts of leeches.

[0039] 2. Preparation method.

[0040] Decoct with 8-10 times water for 3 times, 45 minutes each time, combine the filtrate, concentrate to the specified amount, centrifuge, and pack.

[0041] The beneficial effect of the present invention is illustrated in the mode of experimental example below:

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PUM

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Abstract

The present invention discloses a diabetic nephropathy treating pharmaceutical composition, which is a preparation prepared from the following bulk drugs by weight: 24-36 parts of milkvetch root, 24-36 parts of radix puerariae, 16-24 parts of rosa laevigata michx, 16-24 parts of euryale ferox, 12-18 parts of twig of winged euonymus, 8-12 parts of dodder, 8-12 parts of coptis chinensis, 5-7 parts of rheum palmatum l, 12-18 parts of common yam rhizome, and 7-11 parts of leech. According to the present invention, the diabetic nephropathy treating pharmaceutical composition can effectively treat diabetic nephropathy, provides new selection for clinical medication, and has good clinical application prospects.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating diabetic nephropathy, a preparation method and application thereof. Background technique [0002] Diabetic Nephropathy (DN) is one of the serious microvascular complications of Diabetes Mellitus (DM), and is the main cause of chronic renal insufficiency and end-stage renal disease. , "kidney elimination", "kidney fatigue" and other categories. [0003] In recent years, with the prolongation of human life, the improvement of living standards and the change of lifestyle, the number of diabetic patients has increased significantly, the incidence of DN has also increased, and the harm to human health has become increasingly serious. world's high attention. Irbesartan is a commonly used drug in the treatment of diabetes and its efficacy is good, but there are indigestion, heartburn, diarrhea, musculoskeletal pain, fatigue and upper respiratory tract infection, anxiety, nervousness, chest p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P13/12A61P3/10A61K35/62
Inventor 陈明涂翔
Owner 陈明
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