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External patch for treating liver cirrhosis ascites and preparation method thereof

A technology for liver cirrhosis ascites and a patch, which is applied in the field of traditional Chinese medicine, can solve the problems of troublesome decoction, bitter taste of traditional Chinese medicine decoction, etc., and achieves the effects of simple production process, reduced ascites, and convenient use.

Active Publication Date: 2019-09-03
THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the traditional Chinese medicine therapy for the treatment of liver cirrhosis ascites is mostly oral Chinese medicine preparations, but because the main symptoms of patients with liver cirrhosis ascites are abdominal distension and poor appetite. Even less, there are quite a few patients who refuse to use traditional Chinese medicine decoctions because of their bitter taste and troublesome decoction.

Method used

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  • External patch for treating liver cirrhosis ascites and preparation method thereof
  • External patch for treating liver cirrhosis ascites and preparation method thereof
  • External patch for treating liver cirrhosis ascites and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] An external patch for treating liver cirrhosis ascites, which is composed of the following raw materials: Codonopsis 20g, Radix Astragali 35g, Zeqi 15g, Tinglizi 20g, Wood Beetle 10g, Salvia miltiorrhiza 15g, Borneol 5g, Scallion 40g. After pulverizing and sieving the above-mentioned raw materials, mix them evenly with honey, warm water and skin penetration enhancer (the weight ratio between the total amount of raw materials, honey, warm water and skin penetration enhancer is 30:7:12:3) , made into a sheet and placed in a plasticizer to form an external patch.

Embodiment 2

[0029] An external patch for treating liver cirrhosis ascites, which is composed of the following raw materials: Codonopsis 30g, Radix Astragali 40g, Zeqi 20g, Tinglizi 20g, Wood Beetle 10g, Salvia miltiorrhiza 10g, Borneol 5g, Scallion 40g. After pulverizing and sieving the above-mentioned raw materials, mix them evenly with honey, warm water and skin penetration enhancer (the weight ratio between the total amount of raw materials, honey, warm water and skin penetration enhancer is 30:5:10:2) , made into a sheet and placed in a plasticizer to form an external patch.

Embodiment 3

[0031] An external patch for treating liver cirrhosis ascites, which is composed of the following raw materials: Codonopsis 30g, Radix Astragali 30g, Zeqi 10g, Tinglizi 15g, Wood Beetle 10g, Salvia miltiorrhiza 10g, Borneol 5g, Scallion 30g. After pulverizing and sieving the above raw materials, mix them evenly with honey, warm water and skin penetration enhancer (the weight ratio between the total amount of raw materials, honey, warm water and skin penetration enhancer is 30:10:15:5) , made into a sheet and placed in a plasticizer to form an external patch.

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Abstract

The invention relates to external patch for treating cirrhotic ascites. The external patch comprises 20-30 parts of radix codonopsis, 30-40 parts of radix astragali, 10-25 parts of rhizoma alismatis, 15-30 parts of semen lepidii, 10-20 parts of eupolyphaga seu steleophaga, 10-20 parts of radix salviae miltiorrhizae, 5-10 parts of borneolum syntheticum and 30-50 parts of allium fistulosum. A method for preparing the external patch includes smashing and sieving various bulk medicines for the external patch; uniformly blending the bulk medicines by the aid of honey, warm water and transdermal enhancers; preparing platy mixtures and placing the platy mixtures in excipients to obtain the external patch. The external patch and the method have the advantages that the external patch can be applied to gathering of liquid in abdominal cavities due to various factors and cirrhosis in particular, raw materials for the external patch are low in cost, processes for manufacturing the external patch are simple, and the external patch is convenient to use and can be conveniently accepted by patients.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to an external patch for treating liver cirrhosis ascites and a preparation method thereof, which is applied to accumulation of peritoneal fluid caused by various causes, especially liver cirrhosis. Background technique [0002] Ascites is one of the most common complications of liver cirrhosis, which refers to the accumulation of fluid in the abdominal cavity that exceeds the normal physiological range (200ml). The appearance of ascites indicates that liver cirrhosis has entered the decompensated stage, indicating a poor prognosis and affecting the quality of life of patients. About 50% of patients with compensated liver cirrhosis will develop ascites within 10 years, and about 44% of patients with ascites will die within 5 years. [0003] At present, Western medicine treatment methods for cirrhotic ascites mainly include oral diuretics, abdominal puncture t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8962A61K9/70A61P1/16A61P7/10A61K31/045A61K35/64
Inventor 梁浩卫赵文霞费景兰陈茜钮肖露
Owner THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM
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