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Portable multi-parameter surface plasma resonance biochemical analyzer

A surface plasmon and biochemical analyzer technology, applied in the detection field, achieves the effects of high sensitivity, wide range of incident angles, and reduced volume

Inactive Publication Date: 2017-03-15
INST OF ELECTRONICS CHINESE ACAD OF SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] However, it is worth noting that even BIACORE, which occupies an absolute dominant position in the SPR market, their products are still mainly targeted at scientific research institutes and laboratories; Compared with immunoassay methods, there must be further development in terms of price, ease of use, sensitivity and stability

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  • Portable multi-parameter surface plasma resonance biochemical analyzer
  • Portable multi-parameter surface plasma resonance biochemical analyzer

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Embodiment Construction

[0032] The invention proposes a portable multi-parameter surface plasmon resonance biochemical analyzer, including an optical system, a flow system, a mechanical system, and a control and communication system, wherein: the optical system includes a light source, a photoelectric receiver and an optical prism, and the photoelectric receiver is a multi- Unit array photodetector; the circulation system includes a sensor chip, the sensor chip is mounted above the prism, and the sensor chip is a multi-unit surface plasmon resonance sensor array chip; the incident light is converged into a line by the optical prism and irradiates the sensor. On the sensor chip, after the flow to be measured passes through the upper surface of the multi-unit array sensor chip, it interacts with the reactants fixed on the sensor chip, and the reflected light of multiple arrays is irradiated on the surface of the signal receiver to obtain the surface plasmon of multiple parameters. body resonance signal....

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Abstract

The invention discloses a portable multi-parameter surface plasma resonance biochemical analyzer which comprises an integrated optical system, a mechanical scanning mechanism, a circulation system and a control and communication system. Elements of the optical system are mounted on a mechanical system, and the integrated optical system, the mechanical scanning mechanism and the circulation system are electrically connected with the control and communication system and are connected with a computer through other ports such as a RS32 or a USB (universal serial bus). The multi-parameter surface plasma resonance biochemical analyzer is small in size and provided with a plurality of array units, can meet on-site inspection requirements, different biomolecules or reaction reagents with different concentrations can be fixed on the array units, and a plurality of components are parallelly detected.

Description

technical field [0001] The invention relates to the technical field of detection, in particular to a small portable multi-parameter surface plasmon resonance biochemical analyzer. Background technique [0002] Surface Plasmon Resonance (SPR) technology is a modern, advanced, and general-purpose label-free biochemical detection technology developed in recent years. This technology is a biochemical detection technology based on physical optical phenomena. The evanescent wave (SPW) is used as a probe to detect the change process of the optical parameters of the sensing medium. [0003] Compared with traditional biochemical analysis technology, SPR sensing technology, as a surface detection technology, has the advantages of high sensitivity, label-free, real-time rapid and non-destructive detection, etc., and has been widely used in biotechnology, drug screening, environmental monitoring, Food testing, national security and many other fields have become one of the most general ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/552
CPCG01N21/553
Inventor 崔大付张璐璐蔡浩原李亚亭陈兴徐春方任艳飞
Owner INST OF ELECTRONICS CHINESE ACAD OF SCI
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