Pharmaceutical composition for treatment of uterine myoma

A technology of uterine fibroids and compositions, which is applied in the direction of drug combinations, antineoplastic drugs, and pharmaceutical formulations, and can solve problems such as prolonged menstruation, women's menorrhagia, and affecting women's physical and mental health

Inactive Publication Date: 2017-04-26
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Uterine fibroids is a common gynecological disease at present. In recent years, the incidence has increased sharply. It usually leads to menorrhagia, prolongation of menstrual periods, and lasting for more than half a month. It seriously affects women's physical and mental health. Western medicine generally uses surgical treatment, but Some patients are unwilling to undergo surgery, and the recurrence rate after surgery is still high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1: Pharmaceutical composition for treating uterine fibroids and preparation method thereof

[0035] The composition and weight of the raw materials of the pharmaceutical composition for the treatment of uterine fibroids are: Sword fern 565g, Tengzhong 438g, isotopein 46g, and titonthrin F 35g;

[0036] Preparation:

[0037] (1) According to the ratio of the raw material medicine, take Sword fern, Tengzhong, isodaxanthin, and Typhonium rotundifolia F, mix well, use 32% ethanol as a solvent, and extract at 37°C. The number of times is 26, each extraction time is 0.3 hours, the amount of solvent used each time is 32 times the total weight of the bulk drug, filtered to obtain drug residue A and extract A. Extract A recovers ethanol and concentrates to a relative density of 1.07. After filtration, the drug solution passes through the LD605 macroporous adsorption resin column, first eluted with water, and then eluted the LD605 macroporous adsorption resin column with 41% et...

Embodiment 2

[0040] Example 2: Pharmaceutical composition for treating uterine fibroids and preparation method thereof

[0041] The composition and weight of the raw materials of the pharmaceutical composition for the treatment of uterine fibroids are: Sword fern 562g, Tengzhong 440g, Isodaxanthin 42g, and Tynethrin F 38g;

[0042] Preparation:

[0043] (1) According to the ratio of the raw material medicine, take Sword fern, Tengzhong, isodaxanthin, and Typhonium rotundifolia F, mix well, use 32% ethanol as a solvent, and extract at 37°C. The number of times is 26, each extraction time is 0.3 hours, the amount of solvent used each time is 32 times the total weight of the bulk drug, filtered to obtain drug residue A and extract A. Extract A recovers ethanol and concentrates to a relative density of 1.07. After filtration, the drug solution passes through the LD605 macroporous adsorption resin column, first eluted with water, and then eluted the LD605 macroporous adsorption resin column with 41% ...

Embodiment 3

[0046] Example 3: Pharmaceutical composition for treating uterine fibroids and preparation method thereof

[0047] The composition and weight parts of the raw materials of the pharmaceutical composition for the treatment of uterine fibroids are: Sword fern 568g, Tengzhong 436g, isotopein 48g, and titonthrin F 32g;

[0048] Preparation:

[0049] (1) According to the ratio of the raw material medicine, take Sword fern, Tengzhong, isodaxanthin, and Typhonium rotundifolia F, mix well, use 32% ethanol as a solvent, and extract at 37°C. The number of times is 26, each extraction time is 0.3 hours, the amount of solvent used each time is 32 times the total weight of the bulk drug, filtered to obtain drug residue A and extract A. Extract A recovers ethanol and concentrates to a relative density of 1.07. After filtration, the drug solution passes through the LD605 macroporous adsorption resin column, first eluted with water, and then eluted the LD605 macroporous adsorption resin column with ...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treatment of uterine myoma and a preparing method thereof. The pharmaceutical composition is prepared by proportioning loxogramme chinensis, root or stem of hairyleaf chonemorpha, eupatilin and tagitinin F as raw material medicines, can be made into various dosage forms according to a conventional preparation process, and has remarkable curative effect on treatment of uterine myoma.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a pharmaceutical composition for treating uterine fibroids and a preparation method thereof. Background technique [0002] Uterine fibroids are the most common benign tumors of female reproductive organs, and their incidence is about 25% to 30%. Under normal circumstances, the incidence of women after 30 years of age is very high, reaching 20%. The traditional treatment method is mostly hysterectomy, but the removal of the uterus before menopause can easily make osteoporosis and coronary heart disease appear early. It can also cause menopausal syndrome and make women suffer from endocrine disorders. Traditional surgical removal of the uterus to treat uterine fibroids can not achieve good results, but it will bring a lot of distress to patients' lives. Then, under the premise that the uterus can be preserved, patients with uterine fibroids can be trea...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/24A61P15/00A61P35/00A61K31/365A61K31/352A61K36/12
CPCA61K36/12A61K31/352A61K31/365A61K36/24A61K2236/333A61K2236/39A61K2236/51A61K2236/55
Inventor 不公告发明人
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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