Wormwood-extract-containing itch-relieving ointment and preparation method thereof

The technology of an extract and wormwood, which is applied in the field of antipruritic ointment containing wormwood extract and its preparation, can solve the problems of unfavorable popularization and application, numerous medicinal flavors, and complicated ingredients, and achieve non-toxic and side effects, long-lasting and stable drug effect, The effect of preparation process stability

Inactive Publication Date: 2017-05-31
江西金思康药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There are many types of ointment with antipruritic and antiinflammatory effects on the market, but few are suitable for children. Chinese patent CN 101167811 B discloses an external preparation with antiinflammatory, antipruritic, and bactericidal effects. It can be used as a medicine for treating pruritus skin diseases in children, but the external preparation has many medicinal flavors and complex ingredients, which is not conducive to Promote application

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1. The antipruritic ointment containing wormwood extract of the present invention and its preparation The antipruritic ointment containing wormwood extract in this embodiment is prepared from the following raw materials in parts by weight: 58 parts of wormwood extract, Moringa leaf 22 parts, 26 parts of mountain silver flower, 50 parts of glycerin, 135 parts of liquid paraffin, 114 parts of stearic acid, 9 parts of triethanolamine and 586 parts of water. The weight ratio of described wormwood volatile oil and wormwood alcoholic extract is 0.4: 1;

[0021] The preparation method of the wormwood volatile oil comprises the following steps: take fresh wormwood, grind it and place it in a supercritical carbon dioxide extraction device, control the flow of carbon dioxide to 18L / h, the extraction pressure to 20MPa, the extraction temperature to 32°C, and the extraction time For 1.5h, vacuum separation to obtain wormwood volatile oil, keep the wormwood residue;

[0022...

Embodiment 2

[0027] Example 2, the antipruritic ointment containing wormwood extract of the present invention and its preparation The antipruritic ointment containing wormwood extract in this embodiment is prepared from the following raw materials in parts by weight: 50 parts of wormwood extract, 25 parts, 25 parts of mountain silver flower, 40 parts of glycerin, 140 parts of liquid paraffin, 110 parts of stearic acid, 10 parts of triethanolamine and 600 parts of water.

[0028] The wormwood extract is composed of wormwood volatile oil and wormwood alcohol extract, and the wormwood volatile oil and wormwood alcohol extract

[0029] The weight ratio of wormwood is 0.2: 1; the preparation method of described wormwood volatile oil comprises the steps: get fresh wormwood, place in supercritical carbon dioxide extraction device after being minced, and control carbon dioxide flow rate is 16L / h, and extraction pressure is 20MPa, The extraction temperature is 35°C, the extraction time is 2 hours, ...

Embodiment 3

[0035] Embodiment 3, the antipruritic ointment containing wormwood extract of the present invention and its preparation

[0036] The antipruritic ointment containing wormwood extract in this example is prepared from the following raw materials in parts by weight: 60 parts of wormwood extract, 20 parts of Moringa oleifera leaves, 30 parts of mountain silver flower, 60 parts of glycerin, 130 parts of liquid paraffin, 120 parts of stearic acid, 8 parts of triethanolamine and 572 parts of water.

[0037] The wormwood extract is composed of wormwood volatile oil and wormwood alcohol extract, and the weight ratio of the wormwood volatile oil and wormwood alcohol extract is 0.6: 1;

[0038] The preparation method of the wormwood volatile oil comprises the following steps: take fresh wormwood, grind it and place it in a supercritical carbon dioxide extraction device, control the carbon dioxide flow rate to 20L / h, the extraction pressure to 15MPa, the extraction temperature to 30°C, an...

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PUM

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Abstract

The invention belongs to the field of medicine, and particularly relates to a wormwood-extract-containing itch-relieving ointment and a preparation method thereof. The wormwood-extract-containing itch-relieving ointment comprises the following raw materials in parts by weight: 50-60 parts of wormwood extract, 20-25 parts of Moringa oleifera leaf, 25-30 parts of honeysuckle flower, 40-60 parts of glycerol, 130-140 parts of liquid paraffin, 110-120 parts of stearic acid, 8-10 parts of triethanolamine and 500-650 parts of water. The wormwood-extract-containing itch-relieving ointment, which is prepared from the raw materials above by the preparation method, is mild and hypoallergenic, can quickly relieve itching and resist inflammation, can effectively kill and inhibit bacteria, and can be used for treating cutaneous pruritus for children.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to an antipruritic ointment containing wormwood extract and a preparation method thereof. Background technique [0002] Pruritus skin diseases in children mainly include prickly heat, summer dermatitis, eczema, measles, etc., which are common and frequently-occurring diseases in pediatrics, and seriously endanger the health of children. The current treatment of children's pruritus dermatosis usually adopts anti-allergic chemical drugs, taking traditional Chinese medicine or washing with traditional Chinese medicine. Chemical drugs have large toxic and side effects and many potential risks, so they are not suitable for children to take too much; there are also many problems in the way of taking traditional Chinese medicine or washing Chinese medicine outside, such as poor compliance of taking traditional Chinese medicine, and inaccurate dosage may cause slow or poor curative effec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/355A61K9/06A61K47/44A61K47/18A61P17/04
CPCA61K36/355A61K9/0014A61K9/06A61K36/185A61K36/282A61K2236/333A61K2236/37A61K2236/39
Inventor 曾曜龙
Owner 江西金思康药业有限公司
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