The invention discloses a hand-care liquid detergent. The hand-care liquid detergent is prepared from the following raw materials, by weight, 8-11 parts of fatty alcohol polyoxyethylene ether, 5-7 parts of glycol distearate, 7-9 parts of sodium citrate, 10-12 parts of aloe extracting solution, 5-6 parts of sodium dodecyl sulfate, 4-7 parts of tea tree essential oil, 9-11 parts of Chinese honey locust extracting solution, 12-14 parts of sodium bicarbonate, 10-14 parts of glycerin, 6-8 parts of alkyl glycoside, 4-6 parts of cocamide diethanolamine, 8-13 parts of ethanol and 30-35 parts of water. The hand-care liquid detergent is advantaged by strong decontamination capability, no residuals, high efficiency, rapidness, no damage or stimulation to skin, and effective disinfection and sterilization.