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Chinese medicine compound preparation for treating sepsis and preparation method and application thereof

A technology for compound preparations and sepsis, which can be used in medical formulas, non-central analgesics, medical preparations containing active ingredients, etc., and can solve many problems such as sepsis

Inactive Publication Date: 2017-05-31
方邦江 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although traditional Chinese medicine does not refer to "sepsis", there are many cases of sepsis in clinical practice

Method used

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  • Chinese medicine compound preparation for treating sepsis and preparation method and application thereof
  • Chinese medicine compound preparation for treating sepsis and preparation method and application thereof
  • Chinese medicine compound preparation for treating sepsis and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Weigh 30 grams of raw rhubarb, 30 grams of cooked rhubarb, 150 grams of red vine, 300 grams of astragalus, 100 grams of dandelion, and 150 grams of Aescin. Put cooked rhubarb, red vine, astragalus, dandelion, and aescin into a non-metal container, add 500ml of pure water at room temperature, stir well and soak for 15 minutes, then heat to boiling, after boiling, add raw rhubarb and keep boiling for 5 minutes Minutes later, separate the decoction 250ml and the dregs. Add 500ml of normal temperature purified water to the dregs again, heat to boiling, keep boiling for 3 minutes after boiling, separate and decoct 250ml of liquid. Mix two decoctions, stir evenly, concentrate to 80°C containing crude drug 1.52g / ml medicinal solution, and set aside for later use.

Embodiment 2

[0032]Weigh 60 grams of raw rhubarb, 60 grams of cooked rhubarb, 200 grams of red vine, 450 grams of astragalus, 200 grams of dandelion, and 225 grams of aescin. Put the cooked rhubarb, red vine, astragalus, dandelion, and aescin into a non-metal container, add 1000ml of pure water at room temperature, stir well and soak for 15 minutes, then heat to boiling, after boiling, add raw rhubarb and keep boiling for 5 minutes Minutes later, separate the decoction 400ml and the dregs. Add 1000ml of pure water at normal temperature to the medicinal dregs again, heat to boiling, keep boiling for 3 minutes after boiling, separate and decoct 400ml of liquid. Mix two decoctions, stir evenly, concentrate to 80°C containing crude drug 1.49g / ml medicinal solution, set aside for later use.

Embodiment 3

[0034] Weigh 100 grams of raw rhubarb, 100 grams of cooked rhubarb, 300 grams of red vine, 600 grams of astragalus, 300 grams of dandelion, and 300 grams of Aescin. Put the cooked rhubarb, red vine, astragalus, dandelion, and aescin into a non-metal container, add 1500ml of pure water at room temperature, stir well and soak for 15 minutes, then heat to boiling, after boiling, add raw rhubarb and keep boiling for 5 minutes After 10 minutes, separate the decoction liquid 600ml and medicinal residues. Add 1500ml of pure water at normal temperature to the dregs, heat to boiling, keep boiling for 3 minutes after boiling, separate and decoct 600ml of liquid. Mix two decoctions, stir evenly and concentrate to 80°C containing crude drug 1.42g / ml medicinal solution, set aside for later use.

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Abstract

The invention provides a Chinese medicine compound preparation (sepsis cleansing) for treating sepsis. The Chinese medicine compound preparation is prepared from, by weight, 3-10 parts of raw rhubarb, 3-10 parts of cooked rhubarb, 15-30 parts of sergeant gloryvine, 30-60 parts of milkvetch roots, 10-30 parts of dandelions and 15-30 parts of paris polyphylla. The Chinese medicine compound preparation for treating sepsis can lower the level of TNF-alpha, IL-10, reduces damage to gastrointestinal tracts and lungs when sepsis occurs, and can improve Chinese medicine syndromes and APACHE II grading and lower an inflammation index and the level of endotoxin.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation (Pengduqing) for treating sepsis; in addition, the invention also relates to a preparation method and a medical application of the traditional Chinese medicine compound preparation. Background technique [0002] Sepsis refers to the systemic inflammatory response syndrome caused by definite or suspected infection, and its further development can lead to severe sepsis and septic shock, and severe cases can lead to multiple organ failure, which is the main cause of death in emergency and severe cases. brought a huge burden to the national economy. Sepsis has the characteristics of high morbidity, high mortality, and high treatment costs, and it has already posed a serious threat to human health. Although the development of medicine has made great progress in recent years, the situation for the treatment of this disease is still grim. [0003] The pathophysiology of sepsis is q...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/708A61K36/896A61P31/04A61P37/04A61P29/00
CPCA61K36/11A61K36/185A61K36/288A61K36/48A61K36/481A61K36/486A61K36/708A61K36/896A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 方邦江周爽宋景春王林盛凌黎孙丽华俞志刚朱玲郭全王蓓耿赟陈婧瑶陈振翼
Owner 方邦江
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