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Clinical decision support system and method

A clinical decision support and data technology, applied in the field of medical information, can solve the problems of lack of objective support for clinical decision-making, poor clinical referenceability, and low accuracy of decision-making reference information

Inactive Publication Date: 2017-07-21
为朔医学数据科技(北京)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the traditional clinical decision support system based on the medical knowledge base is mainly based on the information in the electronic medical records, and lacks objective support for clinical decision-making at the molecular level. Therefore, the accuracy of the decision-making reference information provided by the traditional clinical decision support system is low. Poor reference

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  • Clinical decision support system and method

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Embodiment 1

[0037] see figure 1 , the embodiment of the present invention provides a clinical decision support system, including: a data analysis management platform 1, a structured evidence-based knowledge base 2 and an intelligent reasoning machine 3 based on a hotspot matrix model;

[0038] Data analysis management platform 1, storing and processing patient data, and generating omics variation data of patients based on biomarker detection data;

[0039]Structured evidence-based knowledge base 2, based on the metadata model, structured storage of clinical phenotype data, biomarker detection data, omics variation data, drug diagnosis and treatment research information, evidence-based clinical notes, and construct clinical phenotype data, biological Association rules among marker detection data, omics variation data, drug diagnosis and treatment research information, and evidence-based clinical annotations;

[0040] The intelligent inference engine 3, according to the patient's clinical ...

Embodiment 2

[0068] An embodiment of the present invention provides a clinical decision support method, which is executed by the clinical decision support system provided in Embodiment 1 above.

[0069] Before implementing clinical decision support through the clinical decision support method, the structured evidence-based knowledge base included in the clinical decision support system is first constructed through the following operations. The specific construction operations include:

[0070] Obtain medical research literature, based on the matching metadata model, structurally extract clinical phenotype data, biomarker detection data, omics variation data, drug diagnosis and treatment research information and evidence-based clinical annotations recorded in medical research literature; In the evidence-based knowledge base, clinical phenotype data, biomarker detection data, omics variation data, drug diagnosis and treatment research information and evidence-based clinical notes are structu...

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Abstract

The invention provides a clinical decision support system and method. The system comprises a data analysis management platform, a structured evidence-based knowledge base and an intelligent inference machine, wherein the data analysis management platform stores and processes patient data, detects the data according to biomarkers, and generates omics variation data of the patient; the structured evidence-based knowledge base stores clinical phenotype data, biomarker detection data, the omics variation data, drug diagnosis and treatment research information and evidence-based clinical annotations, and establishes a rule of correlation among the data; and the intelligent inference machine, according to the clinical phenotype data and the omics variation data of the patient, calls the structured evidence-based knowledge base to generate clinical decision reference information. Based on the structured evidence-based knowledge base, omics variation is introduced, so that clinical decision is supported in gene level, and DNA, RNA, protein, metabolome and epigenome level variation is covered; and by performing analysis and evidence-based annotation on the omics variation data, the reference information is provided for the clinical decision, so that the accuracy and reference of clinical decision support are improved.

Description

technical field [0001] The present invention relates to the technical field of medical information, in particular to a clinical decision support system and method. Background technique [0002] With the rapid development of medicine, biomedicine, precision medicine and other fields, it is increasingly difficult for clinicians to update their knowledge to keep pace with the rapidly growing and changing medical knowledge. Therefore, it is necessary to support the clinical decision-making of clinicians and provide reference information for clinicians to improve clinical work efficiency and reduce the rate of medical errors. [0003] At present, the clinical decision support system that has been developed in related technologies inputs clinical data through the human-computer interface, interprets patient information through an interpreter and an inference engine, and generates clinical conclusions. Most clinical decision support systems are based on the knowledge base of medic...

Claims

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Application Information

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IPC IPC(8): G06F19/00
CPCG16H50/20
Inventor 不公告发明人
Owner 为朔医学数据科技(北京)有限公司
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