A traditional Chinese medicine compound preparation for promoting angiogenesis

A compound preparation and angiogenesis technology, which can be used in pharmaceutical formulations, cardiovascular system diseases, medical preparations with inactive ingredients, etc. , to achieve good angiogenesis regulation activity, improve wall adhesion phenomenon, and increase the effect of feed concentration

Active Publication Date: 2020-12-08
YANTAI UNIV
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the research on the effect of traditional Chinese medicine on angiogenesis mainly selects a single Chinese medicine or active ingredients of traditional Chinese medicine to act on several representative and relatively well-studied regulatory factors and signaling pathways, which cannot reflect the multi-components of Chinese medicine and Chinese medicine compound. , multi-target, and multi-path features, there are certain deficiencies and defects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0027] A traditional Chinese medicine compound preparation for promoting angiogenesis, which comprises:

[0028] Monarch medicine, its weight portion is 65 parts, and it comprises the Qianhu, Rehmannia glutinosa and Atractylodes macrocephala that weight ratio is 3:1:1;

[0029] Ministerial drug, which comprises the following weight components: 10 parts of raw southern star, 10 parts of Radix Ophiopogon japonicus, 8 parts of woody fragrance, 6 parts of Citrus aurantii and 6 parts of Schisandra;

[0030] Adjuvant, which includes the following components by weight: 30 parts of Cornus officinalis, 20 parts of tea tree roots and 10 parts of ginger;

[0031] Make medicine, it comprises the Radix Paeoniae Alba of 12 weight parts.

[0032] The components of the traditional Chinese medicine compound preparation are cleaned, dried, and pulverized into particles with a particle size of less than 300 μm, mixed uniformly, and then subjected to dynamic extraction with hot water at 93°C for...

example 2

[0035] A traditional Chinese medicine compound preparation for promoting angiogenesis, which comprises:

[0036] Monarch medicine, its weight portion is 65 parts, and it comprises the Qianhu, Rehmannia glutinosa and Atractylodes macrocephala that weight ratio is 3:1:1;

[0037] Ministerial drug, which comprises the following weight components: 12 parts of raw southern star, 12 parts of Radix Ophiopogon, 12 parts of woody fragrance, 8 parts of Citrus aurantii and 8 parts of Schisandra;

[0038] Adjuvant, which includes the following components by weight: 50 parts of Cornus officinalis, 40 parts of tea tree roots and 15 parts of ginger;

[0039] Make medicine, it comprises the Radix Paeoniae Alba of 12 weight parts.

[0040] The components of the traditional Chinese medicine compound preparation are cleaned, dried, and crushed into particles with a particle size of less than 300 μm. After mixing evenly, they are then subjected to dynamic extraction with hot water at 95°C for 50...

example 3

[0044] A traditional Chinese medicine compound preparation for promoting angiogenesis, which comprises:

[0045] Monarch medicine, its weight portion is 65 parts, and it comprises the Qianhu, Rehmannia glutinosa and Atractylodes macrocephala that weight ratio is 3:1:1;

[0046] Ministerial drug, which comprises the following weight components: 11 parts of raw southern star, 11 parts of Radix Ophiopogon japonicus, 10 parts of woody fragrance, 7 parts of Citrus aurantii and 7 parts of Schisandra;

[0047] Adjuvant, which comprises the following weight components: 40 parts of Cornus officinalis, 30 parts of tea tree roots and 12 parts of ginger;

[0048] Make medicine, it comprises the Radix Paeoniae Alba of 12 weight parts.

[0049] The components of the traditional Chinese medicine compound preparation were cleaned, dried, and crushed into particles with a particle size of less than 300 μm, mixed uniformly, and then subjected to dynamic extraction with hot water at 94°C for 40...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
Login to view more

Abstract

The invention provides a Chinese herbal medicine compound preparation for promoting angiogenesis. The Chinese herbal medicine compound preparation contains the following components in parts by weight: 65 parts of main herb including radix peucedani, radix rehmanniae preparata and bighead atractylodes rhizome at weight ratio of 3:1:1, ministerial drug including 10-12 parts of arisaema aridum, 10-12 parts of radix ophiopogonis, 8-12 parts of elecampane, 6-8 parts of fructus aurantii and 6-8 parts of schisandra chinensis, adjuvant including 30-50 parts of corns officinalis, 20-40 parts of tea tree root and 10-15 parts of fresh ginger and conductant drug including 12 parts of radix paeoniae alba. The Chinese herbal medicine compound preparation provided by the invention is based on the principle of assistant and guide, the composition is reasonable in compatibility, various medicinal materials mutually coordinate and match with one another and the Chinese herbal medicine compound preparation has toxicity-reducing and synergic effect and has excellent angiogenesis adjusting activity. A spray drying technology is adopted and the compound ingredients prepared from dextrin, galactose, lactitol and SiO2 are added into the Chinese traditional medicine extract provided by the invention, so that the wall adhering phenomenon in the spray drying process of the Chinese traditional medicine extract is improved under the synergic effect, and meanwhile, the feeding concentration of the spray drying is increased and the time and energy consumption of the spray drying are obviously reduced.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation. More specifically, the present invention relates to a Chinese medicine compound preparation for promoting angiogenesis. Background technique [0002] Angiogenesis refers to the process of generating new capillaries from existing blood vessels through the proliferation and migration of vascular endothelial cells. Angiogenesis plays an important role in physiological and pathological processes such as embryonic development, wound healing, periodic proliferation of endometrium, tumors, and proliferative retinopathy. By improving and regulating the unbalanced process of angiogenesis in the body, the purpose of treating corresponding diseases can be achieved. By promoting angiogenesis, many diseases with insufficient angiogenesis can be treated, such as ischemic heart disease, delayed trauma and fracture healing, vasculitis obliterans, etc., which has become a new strategy for t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K9/16A61K9/14A61K47/36A61K47/26A61K47/04A61P9/00
CPCA61K9/143A61K9/145A61K9/146A61K9/1611A61K9/1623A61K9/1652A61K36/23A61K36/284A61K36/285A61K36/40A61K36/57A61K36/65A61K36/71A61K36/752A61K36/79A61K36/804A61K36/82A61K36/8884A61K36/8968A61K36/9068A61K2300/00
Inventor 李春梅高永林
Owner YANTAI UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap