A traditional Chinese medicine compound preparation for promoting angiogenesis

Abstract

The invention provides a Chinese herbal medicine compound preparation for promoting angiogenesis. The Chinese herbal medicine compound preparation contains the following components in parts by weight: 65 parts of main herb including radix peucedani, radix rehmanniae preparata and bighead atractylodes rhizome at weight ratio of 3:1:1, ministerial drug including 10-12 parts of arisaema aridum, 10-12 parts of radix ophiopogonis, 8-12 parts of elecampane, 6-8 parts of fructus aurantii and 6-8 parts of schisandra chinensis, adjuvant including 30-50 parts of corns officinalis, 20-40 parts of tea tree root and 10-15 parts of fresh ginger and conductant drug including 12 parts of radix paeoniae alba. The Chinese herbal medicine compound preparation provided by the invention is based on the principle of assistant and guide, the composition is reasonable in compatibility, various medicinal materials mutually coordinate and match with one another and the Chinese herbal medicine compound preparation has toxicity-reducing and synergic effect and has excellent angiogenesis adjusting activity. A spray drying technology is adopted and the compound ingredients prepared from dextrin, galactose, lactitol and SiO2 are added into the Chinese traditional medicine extract provided by the invention, so that the wall adhering phenomenon in the spray drying process of the Chinese traditional medicine extract is improved under the synergic effect, and meanwhile, the feeding concentration of the spray drying is increased and the time and energy consumption of the spray drying are obviously reduced.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation. More specifically, the present invention relates to a Chinese medicine compound preparation for promoting angiogenesis. Background technique [0002] Angiogenesis refers to the process of generating new capillaries from existing blood vessels through the proliferation and migration of vascular endothelial cells. Angiogenesis plays an important role in physiological and pathological processes such as embryonic development, wound healing, periodic proliferation of endometrium, tumors, and proliferative retinopathy. By improving and regulating the unbalanced process of angiogenesis in the body, the purpose of treating corresponding diseases can be achieved. By promoting angiogenesis, many diseases with insufficient angiogenesis can be treated, such as ischemic heart disease, delayed trauma and fracture healing, vasculitis obliterans, etc., which has become a new strategy for t...

AI Technical Summary

Problems solved by technology

At present, the research on the effect of traditional Chinese medicine on angiogenesis mainly selects a single Chinese medicine or active ingredients of traditional Chinese medicine to act on several representative and relatively well-studied regulatory factors and signaling pathways, which cannot reflect the multi-components of Chinese medicine and Chinese medicine compound. , multi-target, and multi-path features, there are certain deficiencies and defects