Dendropanax dentiger(Harms)Merr. extract, preparation method and application in medicine for treating rheumatoid arthritis

A technology of extract and tree ginseng, which is applied in the preparation and application of tree ginseng extract, can solve the problems of difficult control of disease development and difficult detection of early diagnosis, and achieve the effect of less drug resistance and less side effects

Inactive Publication Date: 2017-11-10
YICHUN UNIVERSITY
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Problems solved by technology

The challenge in the management and control of rheumatoid arthritis is that it is difficult to detect early diagnosis and difficult to control the development of the disease

Method used

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  • Dendropanax dentiger(Harms)Merr. extract, preparation method and application in medicine for treating rheumatoid arthritis
  • Dendropanax dentiger(Harms)Merr. extract, preparation method and application in medicine for treating rheumatoid arthritis
  • Dendropanax dentiger(Harms)Merr. extract, preparation method and application in medicine for treating rheumatoid arthritis

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Embodiment Construction

[0045] The method of the present invention will be further described in detail below in conjunction with specific embodiments. In the following specific embodiments, it is used to describe the treatment of rheumatoid arthritis in the form of ginseng water.

[0046] 1. Rat model of rheumatoid arthritis,

[0047] Rheumatoid arthritis is a systemic autoimmune disease mainly characterized by chronic joint inflammation, and its pathogenesis has not been fully studied. Clinically, patients with rheumatoid arthritis have acute inflammatory reactions in the acute phase of lesions, such as joint inflammation, synovial hyperemia, swelling, and loose tissue; chronic lesions are characterized by irregular thickening of synovial tissue and damage to articular cartilage, etc. The persistent hyperplasia of the synovium and the destruction of cartilage and bone are its important pathological features. There are two classic animal models of rheumatoid arthritis in rats: one is the collagen-i...

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Abstract

The invention provides a dendropanax dentiger(Harms)Merr. extract, a preparation method and application in medicine for treating rheumatoid arthritis. According to an extraction method of the dendropanax dentiger(Harms)Merr. extract, dendropanax dentiger(Harms)Merr. plant branches are used as raw materials, water is used as an extractant, and the water extraction process is adopted; and the method includes the steps that firstly, the dendropanax dentiger(Harms)Merr. plant branches are cut into the shape of traditional Chinese medicine decoction pieces; secondly, dendropanax dentiger(Harms)Merr. filtrate is prepared; and thirdly, the dendropanax dentiger(Harms)Merr. extract is prepared. According to the application of the dendropanax dentiger(Harms)Merr. extract in preparation of medicine preparations for preventing and treating rheumatic arthritis and rheumatoid arthritis, and the preparation is selected from pharmaceutical preparations including but not limited to water aqua, granular preparations, capsules, powder and the like of the dendropanax dentiger(Harms)Merr. extract, or is a biological preparation. Meanwhile, application of the dendropanax dentiger(Harms)Merr. extract to prevention and treatment of rheumatic arthritis and rheumatoid arthritis diseases is disclosed, the dendropanax dentiger(Harms)Merr. extract has a good treatment effect, and the dendropanax dentiger(Harms)Merr. extract has the beneficial effects of being small in side effect, not likely to cause drug resistance, affordable and the like when used for preventing and treating rheumatic arthritis and rheumatoid arthritis.

Description

Technical field: [0001] The invention belongs to the technical field of preparation and application of tree ginseng extract, and in particular relates to a tree ginseng extract, its preparation method and its application in medicine for treating rheumatoid arthritis. Background technique: [0002] tree ginseng ( Dendropanax dentiger (Harms) Merr. ) for Araliaceae ( Araliaceae ) is a kind of medicinal plant, and the plant classification tree participation ginseng belongs to the same family. Araliaceae plants have many uses in medicine. Ginseng, Panax notoginseng, and Wujiapi are famous medicinal materials. It is in the same family as the well-known traditional Chinese medicines ginseng, Wujiapi, and Panax notoginseng. At present, plant taxonomy experts believe that there are dozens of different species similar to tree ginseng. The shape is similar and the genetics may be distant relatives. Mainly distributed in Jiangxi, Guangdong, Guangxi, Fujian, Hunan, Zhejiang and oth...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/25A61P19/02A61P29/00
CPCA61K36/25A61K2236/17A61K2236/331A61K2236/39A61K2236/51
Inventor 邹一平刘智凯韩成云陈刚
Owner YICHUN UNIVERSITY
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