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A traditional Chinese medicine preparation for clearing heat, detoxification, anti-inflammation and detumescence and preparation method thereof

A technology for clearing away heat and detoxification, and traditional Chinese medicine preparations. It is applied in the directions of anti-inflammatory agents, antidote, antipyretics, etc. It can solve the problems of unstable product quality, uneven drug distribution, and increase stirring power, so as to promote the growth of gastrointestinal beneficial microorganisms. , reduce the incidence of spleen and stomach weakness, enhance the effect of resistance

Active Publication Date: 2020-06-26
GUANGDONG ROC MEDICINAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The "Pudilan Anti-inflammatory Oral Liquid" recorded in the first part of the 2015 edition of "Chinese Pharmacopoeia" provides the prescription and preparation method of the oral liquid. Lan Xiaoyan Oral Liquid is heat-clearing and detoxifying, not suitable for patients with weak spleen and stomach, and for children, the oral liquid has a fast absorption rate, which is easy to stimulate the body and cause allergic reactions. "Report and Analysis of 3 Cases" describes the adverse reactions of Pudilan Xiaoyan Oral Liquid mainly in the damage of the digestive system, skin and accessories. Therefore, it is very important to reduce the adverse reactions of Pudilan Xiaoyan Oral Liquid
[0005] The Chinese patent application with the publication number CN104983805A discloses a pudilan anti-inflammatory film-coated tablet, which is mainly composed of four traditional Chinese medicines, scutellaria baicalensis, dandelion, kudiding, and isatidis. Unstable quality and other problems, but the auxiliary materials used in this invention are starch components, starch is easy to cause gelatinization due to high temperature during the mixing process, resulting in uneven drug distribution, increasing stirring power, and Scutellaria baicalensis fine powder, fiber High content, the active ingredients are not easy to absorb, resulting in waste of raw materials

Method used

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  • A traditional Chinese medicine preparation for clearing heat, detoxification, anti-inflammation and detumescence and preparation method thereof
  • A traditional Chinese medicine preparation for clearing heat, detoxification, anti-inflammation and detumescence and preparation method thereof
  • A traditional Chinese medicine preparation for clearing heat, detoxification, anti-inflammation and detumescence and preparation method thereof

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Embodiment 1

[0027] Embodiment 1 A kind of Chinese medicine preparation for clearing away heat and detoxification, anti-inflammatory and detumescence

[0028] The traditional Chinese medicine preparation consists of the following components and parts by weight: 6 parts of drug carrier, 11 parts of plant fiber inclusion agent, 6 parts of adhesive, 0.15 parts of β-carotene, 1.3 parts of tremella polysaccharide, 1.5 parts of lecithin, dandelion 500 parts, 188 parts of Radix Isatidis, 125 parts of Kudiding and 188 parts of Scutellaria baicalensis;

[0029] The drug carrier is composed of beeswax, talcum powder and modified calcium alginate in a weight ratio of 6:5:1, wherein the preparation method of the modified calcium alginate is: calcium alginate, poly-L-arginine The hydrochloride was mixed in a weight ratio of 3:1, heated in a water bath for 1.5 hours, and cooled to room temperature to obtain the product;

[0030] Described binding agent is made up of polyethylene glycol-400 and sodium h...

Embodiment 2

[0039] Embodiment 2 A kind of Chinese medicinal preparation for clearing heat and detoxification, anti-inflammatory and detumescence

[0040] The traditional Chinese medicine preparation consists of the following components and parts by weight: 5 parts of drug carrier, 12 parts of plant fiber inclusion agent, 5 parts of binder, 0.1 part of β-carotene, 1.5 parts of tremella polysaccharide, 2 parts of lecithin, dandelion 550 parts, 160 parts of Radix Isatidis, 150 parts of Kudiding and 160 parts of Scutellaria baicalensis;

[0041] The drug carrier is composed of beeswax, talcum powder and modified calcium alginate in a weight ratio of 5:6:1, wherein the preparation method of the modified calcium alginate is: calcium alginate, poly-L-arginine Hydrochloride is mixed in a weight ratio of 2:1, heated in a water bath for 1 hour, and cooled to room temperature to obtain the product;

[0042] The binder is composed of polyethylene glycol-400 and sodium hydroxymethyl cellulose in a we...

Embodiment 3

[0048] Embodiment 3 A kind of Chinese medicinal preparation for clearing heat and detoxification, anti-inflammatory and detumescence

[0049] The traditional Chinese medicine preparation consists of the following components and parts by weight: 8 parts of drug carrier, 10 parts of plant fiber inclusion agent, 7 parts of binder, 0.2 part of β-carotene, 1 part of tremella polysaccharide, 1 part of lecithin, dandelion 450 parts, Radix Radix 220 parts, Kudiding 100 parts and Scutellaria baicalensis 210 parts;

[0050] The drug carrier is composed of beeswax, talcum powder and modified calcium alginate in a weight ratio of 7:4:1, wherein the preparation method of modified calcium alginate is: calcium alginate, poly-L-arginine The hydrochloride was mixed in a weight ratio of 4:1, heated in a water bath for 2 hours, and cooled to room temperature to obtain the product;

[0051] The binder is composed of polyethylene glycol-400 and sodium hydroxymethyl cellulose in a weight ratio of ...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine preparation for clearing away the internal heat, removing the toxicity and eliminating the inflammation and swelling and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is mainly prepared from the following components in parts by weight: 5 to 8 parts of drug carriers, 10 to 12 parts of plant fiber inclusion agent, 5 to 7 parts of binder, 0.1 to 0.2 part of beta-carotene, 1 to 1.5parts of tremella polysaccharide, 1 to 2 parts of lecithin, 450 to 550 parts of dandelion, 160 to 220 parts of radix isatidis, 100 to 150 parts of herba corydalis bungeanae, and 160 to 210 parts of radix scutellariae. The traditional Chinese medicine preparation obtained by the invention overcomes the unfavorable response such as weakness of the spleen and the stomach caused by main drug ingredients and improves the stability of the medicine.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine preparation for clearing heat, detoxification, anti-inflammation and detumescence and a preparation method thereof. Background technique [0002] Traditional Chinese medicine preparations are guided by the theory of traditional Chinese medicine and produced by modern technology. Among them, the formulation of traditional Chinese medicine, preparation theory, production technology, and quality control all affect the efficacy of traditional Chinese medicine preparations. Among them, high efficacy, small side effects, and stability Good and high bioavailability are the main research directions of existing traditional Chinese medicine preparations. [0003] Pudilan Xiaoyan Oral Liquid is a common traditional Chinese medicine preparation for clearing heat and detoxifying. This product has a certain inhibitory...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/66A61K9/20A61P39/02A61P29/00A61P37/04A61K31/015A61K31/715
Inventor 王一飞马婧高旭华贺长虹
Owner GUANGDONG ROC MEDICINAL TECH CO LTD
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