Application of endoplasmic reticulum Ca2+ blocker to prepare medicine for treating bone arsenic poisoning
A blocker and endoplasmic reticulum technology, applied in the field of medicine, can solve problems such as unclear mechanism and less research, achieve strong theoretical and practical significance, improve bone condition, and reduce the effect of arsenic toxicity
Inactive Publication Date: 2018-01-16
姜玉峰
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[0044] The main experimental instruments are listed in Table 2.
[0045] Table 2. Description of Experimental Instruments
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[0048] The main experimental reagents are listed in Table 3.
[0049] Table 3. Description of experimental reagents
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The invention discloses an application of an endoplasmic reticulum Ca2+ blocker to prepare a medicine for treating bone arsenic poisoning, and relates to the technical field of a medicine. The endoplasmic reticulum Ca2+ blocker is dantrolene and / or 2-amino carbethoxy diphenylboric acid. The Ca2+ blocker can relieve or improve arsenic poisoning infected by the bone, and provides a new approach to treat bone arsenic poisoning.
Description
technical field [0001] The invention relates to the field of medicine, in particular to endoplasmic reticulum Ca 2+ Application of blocking agent in preparation of medicine for treating bone arsenic poisoning. Background technique [0002] In recent years, the toxicity of arsenic has significantly affected human life and health. Long-term exposure to the environment containing arsenic and arsenic compounds will have many adverse effects on human health, including skin pigmentation, abnormal keratosis, respiratory diseases, gastrointestinal disorders, anemia and splenomegaly, related Birth defects, cardiovascular dysfunction, renal failure, etc. in newborns, while increasing the risk of lung cancer, skin cancer and other cancers in healthy people. Arsenic exposure in humans has many adverse health effects including not only increased risk of various forms of cancer and some benign diseases, but also neurological effects due to occupational or environmental exposure or accid...
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IPC IPC(8): A61K45/06A61K45/00A61K31/69A61K31/4178A61P39/02A61P19/08
Inventor 姜玉峰吕海龙秦文娟
Owner 姜玉峰