Eucommia ulmoides processing method

A preparation method and technology of Eucommia, applied in the field of pharmaceutical engineering, can solve problems such as content influence, and achieve the effect of good prediction results

Inactive Publication Date: 2018-02-16
SHAANXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, different processing methods will have a certain impact on the content of pinoresinol diglucoside and chlorogenic acid in the active ingredients of Eucommia ulmoides

Method used

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Experimental program
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Embodiment Construction

[0015] The technical solutions of the present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0016] 1 material

[0017] 1.1 Instrument

[0018] Agilent-1200 HPLC system (Agilent Technologies Co., Ltd.); BP211D electronic balance (Germany Sartorius Group); electric frying pan (Zhejiang Supor Co., Ltd.)

[0019] 1.2 Reagent

[0020] Reference substance pinoresinol diglucoside (National Institute for Food and Drug Control, batch number: 111537-201605, content: 94.6%); chlorogenic acid (National Institute for Food and Drug Control, batch number: 110753-201415, content: 96.2%); Eucommia ulmoides (provided by Jiangxi Xuanhao Chinese Herbal Pieces Co., Ltd.); other reagents were of analytical grade.

[0021] 2 Methods and results

[0022] 2.1 Chromatographic conditions

[0023] 2.1.1 Determination method of pinoresinol diglucoside

[0024] Column: C 18 Silane-bonded silica gel column (250mm×4.6mm); ...

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Abstract

The invention discloses a processing method of eucommia ulmoides, which comprises the following steps: taking about 250 g of eucommia ulmoides decoction pieces, adding salt water, soaking for 30 minutes, taking it out, adding it into a frying container for frying, taking it out to dry after finishing, crushing and passing through an 80-mesh sieve, The salt concentration is 1.0%-2.1%, the processing temperature is 250°C-400°C, and the processing time is 10min-25min. The present invention uses the Box-Behnken response surface method to optimize the processing parameters of Eucommia ulmoides, and the prediction result is good, which provides a theoretical basis for processing Eucommia ulmoides by salt broiling.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical engineering, and in particular relates to a method for processing Eucommia ulmoides. Background technique [0002] Medicinal Eucommia ulmoides Oliver is the dry bark of Eucommia ulmoides. It is a precious nourishing medicinal material in my country. It is sweet in taste and warm in nature. Efficacy, it can treat lumbago and leg pain or weakness caused by kidney yang deficiency, weak fetus caused by liver qi deficiency, damp and itchy scrotum, etc. It is listed as the top grade in "Shen Nong's Herbal Classic". Modern pharmacological research shows that Eucommia has anti-inflammatory and anti-virus effects, improves human cell activity, accelerates the metabolism of harmful substances in the body, slows down the degeneration of bone and muscle tissue, and lowers blood pressure and blood lipids. [0003] At present, various processing methods of Eucommia ulmoides have been reported in the prio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/46
CPCA61K36/46A61K2236/10
Inventor 张小飞果秋婷孙静史亚军赵重博邹俊波郭东艳王昌利唐志书刘晓莉王媚王晶程江雪
Owner SHAANXI UNIV OF CHINESE MEDICINE
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