Adjustable cell-culture dish scratch device

Abstract

The invention discloses an adjustable cell-culture dish scratch device which is composed of a worktable mechanism, an operating mechanism and a control mechanism, wherein the operating mechanism and the control mechanism are respectively arranged on the worktable mechanism; during use, a culture dish is arranged on a worktable plate, the operating mechanism can move up and down on a lifting rod, the cell scratch depth can be observed through a display screen, and by meshing a gear and a gear groove, back-and-forth movement of a scraper device can be adjusted, and the cell scratch length can beobserved through the display screen. The adjustable cell-culture dish scratch device disclosed by the invention is scientific and reasonable in structure and convenient to operate, scratch with fixedwidth and depth can be accurately performed, the scratch depth can be adjusted, the flooring material on the lower part of cells is not influenced, the scratch positioning is accurate, the scratch width can be scratched according to different scratching tools, and the cell migration ability level can be observed. The adjustable cell-culture dish scratch device comprises a camera assisted system and can perform fine width and depth adjustment, and the cell scratch quality is improved.

Description

technical field [0001] The invention relates to a medical device, in particular to an adjustable cell culture dish scratching device. Background technique [0002] The formal term of cell culture in biology is cell culture technology. No matter for the whole bioengineering technology or one of the biological cloning technology, cell culture is an indispensable process. Cell culture itself is the growth of cells. scale cloning. Cell culture technology can transform a single cell into simple single cell or rarely differentiated multi-cell through mass culture, which is an essential part of cloning technology, and cell culture itself is cell cloning, and a large number of cells or Its metabolites, because biological products are all obtained from cells, so it can be said that cell culture technology is the core and basic technology in biotechnology. [0003] The cell scratch test refers to culturing cells on a petri dish or plate, drawing a line in the central area after the ...

AI Technical Summary

Problems solved by technology

[0005] Hard scratches appear on the culture dish: The purpose of scratches is often used to assess the ability of cell migration. Manual scratches often require weeks of manual practice to scratch on the cell plate that needs to be tested. Manual scratches appear hard on the plate. Scratches are also common, affecting the observation of cell migration. The width of manual scratches cannot be grasped, and the width of scratches cannot be determined by using the tip of the sample pipette. The randomness is strong, and the depth of manual scratches cannot be controlled. Unable to flatly attach residual cells to the bottom of the culture dish, manual scratching and comparison of the scratches on the two culture dishes are inconsistent, often because the scratch width is inconsistent and the comparison is not objective enough, the manual scratch width cannot be accurate to the scale, and the positioning is not accurate. Observe the migration degree at the same position many times. After manual scratches, the positioning position cannot be accurately located. After manual scratches, the scratches are often not straight and smooth, and the observation effect is not good. Manual scratches cannot be retained on the culture dish. The culture material or gel is tiled at the bottom, or the cells are multi-layered, and the bottom material with a fixed thickness cannot be preserved by manual scratching

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