Tracheal intubation method for big and small mice

Abstract

The invention provides a tracheal intubation method for big and small mice. The method includes the following steps of preparing animals and instruments; putting a simple laryngoscope into an oral cavity of a big mouse or a small mouse to expose the glottis of the big mouse or the small mouse; inserting a tracheal catheter into the trachea of the big mouse or the small mouse under orthophoria; connecting the tail end of the tracheal catheter with a breathing machine for small animals and an anesthesia machine for the small animals, and continuing conducting inhalation anesthesia and mechanicalventilation. The tracheal intubation method for the big and small mice is wide in application range, high in success rate, applicable to molding of the big and small mice different in size, medicineapplication for tracheas, lung function detection and other occasions, and capable of avoiding the situation the the success rate of blind intubation is low, and damage is caused to the bodies of animals; the applied instruments are adaptive to the characters that the glottises of the big and small mice are narrow and the tracheas of the big and small mice are located at the deep portions of the oral cavities, pain caused by organic damage during intubation is reduced, and the stress reaction of the animals to the intubation is small; the operation is simple, and one person can complete all operation.

Description

technical field [0001] The invention relates to the field of tracheal intubation, in particular to a method for tracheal intubation of large and small mice. Background technique [0002] In medicine and biology, mice and rats are commonly used for experiments. In the experiments, it is often necessary to intubate mice and rats for mechanical ventilation or tracheal administration. Currently available intubation methods include blind intubation, tracheotomy, and direct vision intubation. [0003] The blind insertion method is easy to insert into the esophagus, the success rate is low, and it needs repeated trials. It is easy to damage the pharynx of mice and rats, resulting in the secretion of a large amount of mucus that affects the administration, and it is easy to cause infection. The pathological state increases the error of the whole experimental process. [0004] The tracheotomy method needs to incise the neck skin of rats, separate and expose the trachea layer by lay...

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide a method for tracheal intubation of large and small mice, which can solve the problems of easy damage to the pharynx, easy infection and large manpower input during tracheal intubation of large and small mice

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