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Medicine composition for resisting hepatitis C, preparation method, preparation and application thereof

A kind of technology of hepatitis C and composition, applied in the field of medicine, can solve the problems such as the difficult problem of treatment of hepatitis C, serious side effects of drugs and the like that cannot be fundamentally solved

Inactive Publication Date: 2018-02-27
广州医问医药生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The drugs in the above schemes all have relatively large side effects, and cannot fundamentally solve the problem of hepatitis C treatment

Method used

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  • Medicine composition for resisting hepatitis C, preparation method, preparation and application thereof
  • Medicine composition for resisting hepatitis C, preparation method, preparation and application thereof
  • Medicine composition for resisting hepatitis C, preparation method, preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Weigh 1g of seabuckthorn and ultrafinely pulverize it to obtain material a, weigh 10g of astragalus, 20g of heterophylla, 10g of frondosa frondosa, 1g of gallinaceous gold, 10g of poria cocos and 5g of Atractylodes macrocephala, add 10 times the weight of water to soak for 1 hour, and then heat up to 80~ Extract at 90°C for 1 hour, then increase the steam pressure and heat to 95-103°C, filter with 60-mesh gauze after 1 hour to obtain the extract, add 8 times the weight of water to the filter residue, and carry out the second leaching under the same conditions The time is 2 hours, and the filtrate is obtained by filtering to remove the slag. The combined two filtrates are concentrated and then pumped into the spray drying tower for drying. The inlet temperature is 190-200°C, and the outlet temperature is 80°C. After drying, it is crushed and passed through an 80-mesh sieve to obtain material b and uniformly mixing material b and material a to obtain the target anti-hepati...

Embodiment 2

[0019] Weigh 10g of seabuckthorn to obtain material a by superfine grinding, simultaneously weigh 20g of astragalus, 40g of heterophylla, 20g of frondosa frondosa, 10g of gallinaceous gold, 20g of poria cocos and 15g of Atractylodes macrocephala, add 10 times the weight of water and soak for 1 hour, and then heat up to Extract at 80-90°C for 1 hour, then increase the steam pressure and heat to 95-103°C, filter with 60-mesh gauze after 1 hour to obtain the extract, add 8 times the weight of water to the filter residue, and carry out the second extraction under the same conditions. The second leaching, the time is 2h, the filtrate is obtained by filtering to remove the slag, the combined two filtrates are concentrated and then pumped into the spray drying tower for drying. Material b, uniformly mixing material b and material a to obtain the target anti-hepatitis C pharmaceutical composition.

Embodiment 3

[0021] Weigh 5g of seabuckthorn to obtain material a by superfine grinding, weigh 15g of astragalus, 30g of heterophylla, 15g of frondosa frondosa, 5g of gallinaceous gold, 15g of poria cocos and 10g of Atractylodes macrocephala, add 10 times the weight of water to soak for 1 hour, and then heat up to 80~ Extract at 90°C for 1 hour, then increase the steam pressure and heat to 95-103°C, filter with 60-mesh gauze after 1 hour to obtain the extract, add 8 times the weight of water to the filter residue, and carry out the second leaching under the same conditions The time is 2 hours, and the filtrate is obtained by filtering to remove the slag. The combined two filtrates are concentrated and then pumped into the spray drying tower for drying. The inlet temperature is 190-200°C, and the outlet temperature is 80°C. After drying, it is crushed and passed through an 80-mesh sieve to obtain material b and uniformly mixing material b and material a to obtain the target anti-hepatitis C ...

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Abstract

The invention discloses a medicine composition for resisting hepatitis C, a preparation method, a preparation and application thereof. The medicine composition for resisting hepatitis C comprises thefollowing raw materials in parts by weight: 10 to 20 parts of Astragalus membranaceus, 20 to 40 parts of radix pseudostellariae, 10 to 20 parts of Grifola frondosa, 1 to 10 parts of seabuckthorn, 1 to10 parts of endothelium corneum gigeriae galli, 10 to 20 parts of Poria cocos and 5 to 15 parts of white atractylodes rhizome. Tablets, powders, capsules, granules and pills prepared from pharmaceutically acceptable ingredients are added into the preparation which is the medicine composition for resisting hepatitis C. The application is the application of the medicine composition for resisting hepatitis C in preparation of medicine for resisting hepatitis C. The medicine composition fundamentally solves the treatment problem of hepatitis C, and is little in side effect and obvious in effect.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an anti-hepatitis C pharmaceutical composition and a preparation method, preparation and application thereof. Background technique [0002] Viral hepatitis C, referred to as hepatitis C, hepatitis C, is a viral hepatitis caused by hepatitis C virus (HCV) infection, mainly through blood transfusion, acupuncture, drug abuse, etc., according to the statistics of the World Health Organization, the global The infection rate of HCV is about 3%, it is estimated that about 180 million people are infected with HCV, and there are about 35,000 new cases of hepatitis C every year. Hepatitis C is a global epidemic, which can lead to chronic inflammation, necrosis and fibrosis of the liver, and some patients can develop liver cirrhosis and even hepatocellular carcinoma (HCC). In the next 20 years, HCV infection-related mortality (death caused by liver failure and hepatocellular c...

Claims

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Application Information

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IPC IPC(8): A61K36/481A61K36/748A61K36/9066A61P1/16A61P31/14A61K35/57
CPCA61K35/57A61K36/07A61K36/076A61K36/185A61K36/284A61K36/36A61K36/481A61K36/486A61K36/537A61K36/539A61K36/57A61K36/634A61K36/748A61K36/79A61K36/9066A61K2236/15A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 赖祖琴冼燃李佳柔李丹李帆霄炫
Owner 广州医问医药生物科技有限公司
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