Solution preparation for atomization inhalation of children Kechuanling and preparation method of solution preparation
A technology for atomized inhalation and infantile cough and asthma, applied in the field of pharmacy, can solve the problems of no suitable dosage form, few products, and no use of atomized inhalation preparations, so as to increase compliance, reduce dosage, and improve safety Effect
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Embodiment 1
[0031] (1) Preparation of active ingredients of Kechuanling for children:
[0032] Ephedra 3.75g, honeysuckle 37.5g, bitter almond 18.75g, isatis root 37.5g, gypsum 56.25g, licorice 18.75g, melon wilt 18.75g
[0033] Weigh the Qiwei medicine according to the above weight parts, add bitter almond, gypsum, isatis root, licorice, melon wilt, add 8 times the amount of water to decoct for 1 hour, filter; Combine the filtrates, let stand, take the supernatant, concentrate to an appropriate amount, add ethanol to make the alcohol content 70%, stir well, let stand, refrigerate for 12 hours, take the supernatant, filter, and recover the ethanol from the filtrate until it has no alcohol smell, Add ethanol again to make the alcohol content to 75%, stir well, let it stand, refrigerate for 12 hours, take the supernatant, filter, recover the ethanol from the filtrate until it has no alcohol smell, add an appropriate amount of water for injection, stir well, refrigerate for 24 hours, take th...
Embodiment 2
[0041] (1) Preparation of active ingredients of Kechuanling for children:
[0042] Ephedra 6.25g, honeysuckle 62.5g, bitter almond 31.25g, isatis root 62.5g, gypsum 93.75g, licorice 31.25g, melon wilt 31.25g
[0043] Weigh the seven herbs according to the above parts by weight, add bitter almonds, gypsum, isatis root, licorice, and melon wilt, add 10 times the amount of water to decoct for 1 hour, filter; Combine the filtrates, let stand, take the supernatant, concentrate to an appropriate amount, add ethanol to make the alcohol content 75%, stir well, let stand, refrigerate for 12 hours, take the supernatant, filter, and recover the ethanol from the filtrate until it has no alcohol smell, Add ethanol again to make the alcohol content 85%, stir well, let it stand, refrigerate for 12 hours, take the supernatant, filter, recover the ethanol from the filtrate until it has no alcohol smell, add an appropriate amount of water for injection, stir well, refrigerate for 36 hours, take...
Embodiment 3
[0051] (1) Preparation of active ingredients of Kechuanling for children:
[0052] Ephedra 2.5g, honeysuckle 25g, bitter almond 12.5g, Radix Radix 25g, gypsum 37.5g, licorice 12.5g, melon wilt 12.5g
[0053] Weigh the seven herbs according to the above parts by weight, add bitter almonds, gypsum, isatis root, licorice, and melon wilt, add 12 times the amount of water to decoct for 1 hour, filter; Combine the filtrate, let it stand still, take the supernatant, concentrate to an appropriate amount, add ethanol to make the alcohol content 80%, stir well, let it stand, refrigerate for 12 hours, take the supernatant, filter, and recover the ethanol from the filtrate until it has no alcohol smell, Add ethanol again to make the alcohol content 85%, stir well, let it stand, refrigerate for 12 hours, take the supernatant, filter, recover the ethanol from the filtrate until it has no alcohol smell, add an appropriate amount of water for injection, stir well, refrigerate for 48 hours, ta...
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