Continuous antibacterial hydrocolloid dressing and preparing method thereof

A hydrocolloid and anti-oxidant technology, which is applied in the fields of pharmaceutical formula, medical science, absorbent pads, etc., can solve the problems of only existing antibacterial effect, inability to achieve long-lasting antibacterial performance, and no antibacterial performance, and achieve strong liquid absorption and moisturizing performance, excellent and durable The effect of antimicrobial properties

Inactive Publication Date: 2018-05-08
GUANGDONG TAIBAO MEDICAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, traditional hydrocolloid dressings have no antibacterial properties, and the effect is often unsatisfactory when dealing with chronic wounds with potential infection risks or mild infections
Some hydrocolloid dressings wil

Method used

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  • Continuous antibacterial hydrocolloid dressing and preparing method thereof
  • Continuous antibacterial hydrocolloid dressing and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A sustained antibacterial hydrocolloid dressing is obtained by mixing and coating styrene-isoprene-styrene block copolymer (SIS), tackifying resin, plasticizer, antioxidant and silver-loaded alginate microspheres , wherein silver-loaded alginate microspheres were prepared by spray drying. The preparation method of the above-mentioned persistent antibacterial hydrocolloid is as follows:

[0028] S1. Preparation of silver-loaded alginate microspheres: dissolving sodium alginate in purified water to obtain a 4wt% alginate solution, and then adding nano-silver with a mass ratio of 1:5 to sodium alginate to the alginate solution Stir evenly to obtain a silver-containing alginate solution, spray the silver-containing alginate solution in an inert hot air stream, and dry it so that the dissolved alginate solution evaporates rapidly, and the alginate shrinks into a shell to form a silver-loaded alginate Microspheres;

[0029] S2. Preparation of hot-melt pressure-sensitive adh...

Embodiment 2

[0032] A sustained antibacterial hydrocolloid dressing is obtained by mixing and coating styrene-isoprene-styrene block copolymer (SIS), tackifying resin, plasticizer, antioxidant and silver-loaded alginate microspheres , wherein silver-loaded alginate microspheres were prepared by spray drying. The preparation method of the above-mentioned persistent antibacterial hydrocolloid is as follows:

[0033] S1. Preparation of silver-loaded alginate microspheres: dissolving sodium alginate in purified water to obtain a 4wt% alginate solution, and then adding nano-silver with a mass ratio of 1:7 to sodium alginate to the alginate solution Stir evenly to obtain a silver-containing alginate solution, spray the silver-containing alginate solution in an inert hot air stream, and dry it so that the dissolved alginate solution evaporates rapidly, and the alginate shrinks into a shell to form a silver-loaded alginate Microspheres;

[0034] S2. Preparation of hot-melt pressure-sensitive adh...

Embodiment 3

[0037] A sustained antibacterial hydrocolloid dressing is obtained by mixing and coating styrene-isoprene-styrene block copolymer (SIS), tackifying resin, plasticizer, antioxidant and silver-loaded alginate microspheres , wherein silver-loaded alginate microspheres were prepared by spray drying. The preparation method of the above-mentioned persistent antibacterial hydrocolloid is as follows:

[0038] S1. Preparation of silver-loaded alginate microspheres: dissolving sodium alginate in purified water to obtain a 4wt% alginate solution, and then adding nano-silver with a mass ratio of 1:9 to sodium alginate to the alginate solution Stir evenly to obtain a silver-containing alginate solution, spray the silver-containing alginate solution in an inert hot air stream, and dry it so that the dissolved alginate solution evaporates rapidly, and the alginate shrinks into a shell to form a silver-loaded alginate Microspheres;

[0039] S2. Preparation of hot-melt pressure-sensitive adh...

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Abstract

The invention belongs to the field of medical dressings, and particularly relates to a continuous antibacterial hydrocolloid dressing and a preparing method thereof. The dressing is composed of a backlining layer, a functional layer dressing core and an isolation layer in sequence from bottom to top. The functional layer dressing core is prepared from, by weight, 15-20 parts of styrene-isoprene-styrene segmented copolymer (SIS), 15-20 parts of viscosity increasing resin, 10-15 parts of plasticizer, 10-15 parts of antioxidant and 30-50 parts of silver-loaded alginate microspheres. The continuous antibacterial hydrocolloid dressing has strong liquid absorption and humidity maintaining performance and has excellent continuous antibacterial performance, nanosilver contained in the hydrophilicsilver-loaded alginate microspheres in hydrocolloid is slowly released out of the silver-loaded alginate microspheres during liquid absorption swelling of alginate after the silver-loaded alginate microspheres make contact with blood or percolate, and the continuous antibacterial aim is achieved.

Description

technical field [0001] The invention belongs to the field of medical devices, in particular to the field of medical biopolymer materials, and specifically relates to a sustained antibacterial hydrocolloid and a preparation method thereof. Background technique [0002] Hydrocolloid dressing is a medical dressing prepared by blending hydrophilic polymer particles with hot-melt pressure-sensitive adhesive. This medical dressing combines the adhesive properties of rubber materials and the water absorption properties of hydrophilic polymer materials. The hydrophilic particles uniformly dispersed in the hydrocolloid dressing swell after absorbing liquid, providing a moist and airtight environment for the wound, promoting Wound healing, a moist environment plays a very good role in promoting wound healing. [0003] However, traditional hydrocolloid dressings have no antibacterial properties, and are often unsatisfactory when dealing with chronic wounds with potential infection ris...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/24A61L15/18A61L15/42A61L15/46A61L15/60
CPCA61L15/18A61L15/24A61L15/28A61L15/42A61L15/46A61L15/60A61L2300/104A61L2300/404A61L2300/602A61L2400/12C08L5/04C08L53/02
Inventor 陈锦涛韦加娜吴帅
Owner GUANGDONG TAIBAO MEDICAL SCI TECH
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