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Oral traditional Chinese medicine composition for treating depressive disorder as well as preparation and preparation method thereof

A technology for depression and composition, applied in the field of oral traditional Chinese medicine composition for treating depression and its preparation and preparation field, can solve the problems of lack of compound preparation products, few varieties of antidepressant traditional Chinese medicine, etc.

Active Publication Date: 2018-06-08
杨添淞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But at present, there are few types of antidepressant traditional Chinese medicines in my country, and there is a lack of compound preparations.

Method used

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  • Oral traditional Chinese medicine composition for treating depressive disorder as well as preparation and preparation method thereof
  • Oral traditional Chinese medicine composition for treating depressive disorder as well as preparation and preparation method thereof
  • Oral traditional Chinese medicine composition for treating depressive disorder as well as preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1 Chinese medicinal oral liquid for treating depression and its preparation

[0035]

[0036] Preparation:

[0037] A. Take the prescribed amount of Bupleurum bupleuri, angelica, white peony root, cassia twig, and elm yellow mushroom, respectively, crush them through a 50-mesh sieve, mix them to obtain coarse powder of medicinal materials, add water to decoct twice, and add water 7 times the weight of coarse powder of medicinal materials for the first time Decoct for 4 hours, add 3 times the weight of the crude medicinal powder for the second time and decoct for 2 hours, filter and combine the decoction, concentrate to a concentrated solution with a relative density of 1.20, let it stand for cooling, add ethanol to the concentrated solution to make the ethanol The volume percentage is 75%, stay overnight at 4°C, filter to remove insoluble matter, collect the filtrate to distill under reduced pressure to remove ethanol, obtain a refined solution, and concen...

Embodiment 2

[0041] Embodiment 2 Chinese medicine oral liquid for treating depression and its preparation

[0042]

[0043] Preparation:

[0044] A. Take the prescribed amount of Bupleurum bupleuri, angelica, white peony root, cassia twig, and elm yellow mushroom, respectively, crush them through a 50-mesh sieve, mix them to obtain coarse powder of medicinal materials, add water to decoct twice, and add water 7 times the weight of coarse powder of medicinal materials for the first time Decoct for 4 hours, add 3 times the weight of the crude medicinal powder for the second time and decoct for 2 hours, filter and combine the decoction, concentrate to a concentrated solution with a relative density of 1.20, let it stand for cooling, add ethanol to the concentrated solution to make the ethanol The volume percentage is 75%, stay overnight at 4°C, filter to remove insoluble matter, collect the filtrate to distill under reduced pressure to remove ethanol, obtain a refined solution, and concent...

Embodiment 3

[0048] Example 3 Chinese medicine oral liquid for treating depression and its preparation

[0049]

[0050] Preparation:

[0051] A. Take the prescribed amount of Bupleurum bupleuri, angelica, white peony root, cassia twig, and elm yellow mushroom, respectively, crush them through a 50-mesh sieve, mix them to obtain coarse powder of medicinal materials, add water to decoct twice, and add water 7 times the weight of coarse powder of medicinal materials for the first time Decoct for 4 hours, add 3 times the weight of the crude medicinal powder for the second time and decoct for 2 hours, filter and combine the decoction, concentrate to a concentrated solution with a relative density of 1.20, let it stand for cooling, add ethanol to the concentrated solution to make the ethanol The volume percentage is 75%, stay overnight at 4°C, filter to remove insoluble matter, collect the filtrate to distill under reduced pressure to remove ethanol, obtain a refined solution, and concentrat...

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Abstract

The invention belongs to the field of traditional Chinese medicines and particularly relates to an oral traditional Chinese medicine composition for treating depressive disorder as well as a preparation and preparation method thereof. The oral traditional Chinese medicine composition is prepared from pharmaceutically acceptable auxiliaries, radix bupleuri, angelica, radix paeoniae alba, ramulus cinnamomi, crinum asiaticum and pleurotus citrinopileatus, wherein radix bupleuri, angelica, radix paeoniae alba, ramulus cinnamomi and pleurotus citrinopileatus are extracted by virtue of a water extraction alcohol precipitation method, and crinum asiaticum is a volatile oil component which has a relative density lower than 1.0 and is extracted by virtue of a vapor distillation method. The dose form of the oral traditional Chinese medicine composition is oral liquid. The oral traditional Chinese medicine composition has good treatment effects on depressive disorder and further has safety.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to an oral Chinese medicine composition for treating depression, its preparation and a preparation method. Background technique [0002] Depression is a mood disorder syndrome. Patients mainly manifest as significant and persistent depression, low self-esteem, pessimism, loss of energy, changes in appetite, more or less sleep, and decreased concentration; lack of desire for social interaction and exploration, Severe patients even have suicidal tendencies. The etiology and pathogenesis of depression are still not fully understood. It is generally believed that depression may be the result of the interaction of physiological, psychological and social factors. The accelerated pace of life and increased work, study and social pressure may be the external environmental factors leading to depression. According to reports, the prevalence of depression in China is...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61K9/08A61P25/24
CPCA61K9/0095A61K36/07A61K36/232A61K36/233A61K36/54A61K36/65A61K36/71A61K36/88A61K47/40A61K2236/331A61K2236/37A61K2300/00
Inventor 杨添淞孙维伯聂宏许骏杨燕王德龙李超然
Owner 杨添淞
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